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1 OMIM reference -
2 associated genes
10 signs/symptoms
PROTEIN INTERACTIONS: 3
6 OMIM references -
7 associated genes
No signs/symptoms info
Apolipoprotein A-I deficiency
B-cell chronic lymphocytic leukemia

ABCA1 ARL11
APOA1 ATM
CCND1
IGHG1
IGHV3-21
()
POT1
TP53


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
ABCA1
APOA1
APOA1
(0.63)
(0.63)
(0.63)
IGHV3-21
IGHG1
IGHV3-21



Citations in the biomedical literature:


Apolipoprotein A-I deficiency
ABCA1 APOA1
B-cell chronic lymphocytic leukemia
ARL11 ATM CCND1 IGHG1 IGHV3-21 POT1
TP53



Apolipoprotein A-I deficiency
B-cell chronic lymphocytic leukemia

Synonym(s):
- ApoA-I deficiency
- Familial apoA-I deficiency
- Familial hypoalphalipoproteinemia

Synonym(s):
- B-CLL
- B-cell chronic lymphoid leukemia
- Lymphoplasmacytic leukemia
- Lymphoplasmacytoid immunocytoma
- Small lymphocytic lymphoma

Classification (Orphanet):
- Inborn errors of metabolism
- Rare endocrine disease
- Rare genetic disease
Classification (Orphanet):
- Rare hematologic disease
- Rare oncologic disease

Classification (ICD10):
- Endocrine, nutritional and metabolic diseases -
Classification (ICD10):
- Neoplasms -

Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: variable
Average age of death: any age
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: 1-5 / 10 000
Average age onset: adulthood
Average age of death: -
Type of inheritance: sporadic

External references:
1 OMIM reference -
1 MeSH reference: D052456
External references:
6 OMIM references -
1 MeSH reference: D015451

Apolipoprotein A-I deficiency

Frequent
- Abnormal EMG / electromyogram / electropmyography
- Abnormal muscle biopsy / muscle enzymes / CPK / LDH / aldolase / creatin phosphokinase
- Anaemia
- Autosomal recessive inheritance
- Hemiplegia / diplegia / hemiparesia / limb palsy
- Hepatitis / icterus / cholestasis
- Hyperlipidemia / hypercholesterolemia / hypertriglyceridemia
- Lymphadenopathy / polyadenopathies
- Splenomegaly
- Storage liver disease



B-cell chronic lymphocytic leukemia

(no data available)