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7 OMIM references -
8 associated genes
5 signs/symptoms
PROTEIN INTERACTIONS: 2
7 associated genes
No signs/symptoms info
46,XY complete gonadal dysgenesis
Pilocytic astrocytoma

CBX2 BRAF
DHH FGFR1
DMRT1 KIAA1549
DMRT2 KRAS
MAP3K1 NTRK2
NR0B1 RAF1
NR5A1 SRGAP3
SRY


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
MAP3K1
MAP3K1
(0.84)
(0.78)
BRAF
RAF1



Citations in the biomedical literature:


46,XY complete gonadal dysgenesis
CBX2 DHH DMRT1 DMRT2 MAP3K1 NR0B1
NR5A1 SRY
Pilocytic astrocytoma
BRAF FGFR1 KIAA1549 KRAS NTRK2 RAF1
SRGAP3



46,XY complete gonadal dysgenesis
Pilocytic astrocytoma

Synonym(s):
- 46,XY CGD
- 46,XY pure gonadal dysgenesis
- Swyer syndrome

Synonym(s):
(no synonyms)

Classification (Orphanet):
- Rare cardiac disease
- Rare circulatory system disease
- Rare developmental defect during embryogenesis
- Rare endocrine disease
- Rare genetic disease
- Rare gynecologic or obstetric disease
- Rare skin disease
- Rare urogenital disease
Classification (Orphanet):
(no data available)

Classification (ICD10):
- Congenital malformations, deformations and chromosomal abnormalities -
Classification (ICD10):
(no data available)

Epidemiological data:
Class of prevalence: unknown
Average age onset: adolescence / young
Average age of death: normal
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: -
Average age onset: variable
Average age of death: -
Type of inheritance: sporadic

External references:
7 OMIM references -
No MeSH references
External references:
No OMIM references
No MeSH references

46,XY complete gonadal dysgenesis

Very frequent
- Abnormal / polycystic ovaries
- Late puberty / hypogonadism / hypogenitalism
- Male pseudohermaphrodism / lack of virilisation
- Small / atrophic / hypoplastic testes / monorchism / microorchidism / anorchia
- X-linked recessive inheritance



Pilocytic astrocytoma

(no data available)