There is a newer version of MBROLE (3.0) available at https://csbg.cnb.csic.es/mbrole3. This old version is maintained only for reproducibility purposes and could be discontinued at any time.
Welcome to MBROLE 2.0
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MBROLE (pronounced as "embrole") performs overrepresentation (enrichment) analysis of categorical annotations for a set of compounds of interest.These categorical annotations correspond to biological and chemical information available in a number of public databases and software.
What's new in version 2.0:
- New databases added: MeSH, YMDB, DrugBank, LIPID MAPS, MATADOR, RHEA, BioCyc, CTD, UniPathway and ECMDB.
Full list of databases» - Metabolite-protein interactions from various databases.
- Automatic ID conversion: you can directly submit any of the supported IDs without need of pre-conversion.
- New pre-compiled organisms datasets from Biocyc.
Go to the help page» for the full list of biological annotations and how to use MBROLE.
References
If you use MBROLE, please cite the following article:
López-Ibáñez, J. Pazos, F. Chagoyen, M. MBROLE 2.0 - Functional enrichment of chemical compounds Nucleic Acids Res. (2016) [Full article]
Feedback
Did you miss some relevant annotations?
Are you interested in adding pre-compiled background sets?
We want to hear from you to improve MBROLE. Please write your comments and suggestions to:
jlopezibanez{at}cnb.csic.es
