>gi|1173139|sp|P46969|RPE_YEAST  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (RPE)
Length=238

 Score =  236 bits (602),  Expect = 7e-62, Method: Composition-based stats.
 Identities = 238/238 (100%), Positives = 238/238 (100%), Gaps = 0/238 (0%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV
Sbjct  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
            PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS
Sbjct  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHL  180
            KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHL
Sbjct  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHL  180

Query  181  NIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRDLLD  238
            NIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRDLLD
Sbjct  181  NIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRDLLD  238


>gi|51701877|sp|Q6FL81|RPE_CANGA  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (RPE)
Length=246

 Score =  223 bits (568),  Expect = 5e-58, Method: Composition-based stats.
 Identities = 200/240 (83%), Positives = 215/240 (89%), Gaps = 3/240 (1%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            MVKPIIAPSILASDFANLGCECH+VIN+GA+WLHIDVMDGHFVPNITLGQPIVTSLRR+V
Sbjct  1    MVKPIIAPSILASDFANLGCECHRVINSGAEWLHIDVMDGHFVPNITLGQPIVTSLRRAV  60

Query  61   PRPGDASNT---EKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKL  117
            PR  +         +PTAFFDCHMMVE PEKWV DFAK GADQFTFHYEAT+DPL LVKL
Sbjct  61   PRSQEEEKASGEVARPTAFFDCHMMVEEPEKWVADFAKAGADQFTFHYEATKDPLSLVKL  120

Query  118  IKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKF  177
            IK  GIKAACAIKPGT VDVLFELAP+LDMALVMTVEPGFGGQKFM DMMPKVE LR KF
Sbjct  121  IKENGIKAACAIKPGTPVDVLFELAPYLDMALVMTVEPGFGGQKFMPDMMPKVEALRTKF  180

Query  178  PHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRDLL  237
            PH+NIQVDGGLGKETI  AAKAGANVIVAGTSVFTA+DPH+VISFMKEEV KEL+++ +L
Sbjct  181  PHMNIQVDGGLGKETIGVAAKAGANVIVAGTSVFTASDPHEVISFMKEEVRKELKAKHIL  240


>gi|51701884|sp|Q755M2|RPE_ASHGO  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (RPE)
Length=239

 Score =  214 bits (545),  Expect = 3e-55, Method: Composition-based stats.
 Identities = 191/238 (80%), Positives = 204/238 (85%), Gaps = 2/238 (0%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            MVKPIIAPSILASDFANL C CH+VINAGA+WLHIDVMDGHFVPNITLG PIV SLR++V
Sbjct  1    MVKPIIAPSILASDFANLECGCHRVINAGAEWLHIDVMDGHFVPNITLGPPIVKSLRKAV  60

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
            PR G       KP AFFDCHMMV  PEKWVD F + GADQFTFHYEAT++PL LVKLIKS
Sbjct  61   PRVG--DKESDKPKAFFDCHMMVAEPEKWVDVFVENGADQFTFHYEATKNPLELVKLIKS  118

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHL  180
            +GI+AACAIKP T VDVLFELAP+LDMALVMTVEPGFGGQKFM DMMPKV  LR KFP L
Sbjct  119  RGIRAACAIKPDTPVDVLFELAPYLDMALVMTVEPGFGGQKFMPDMMPKVAALREKFPQL  178

Query  181  NIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRDLLD  238
            +IQVDGGLGKETIP AAKAGANVIVAGTSVF AAD  DVIS+MK+ V  ELRSR LLD
Sbjct  179  DIQVDGGLGKETIPHAAKAGANVIVAGTSVFAAADQKDVISYMKDNVRDELRSRGLLD  236


>gi|34924986|sp|Q96AT9|RPE_HUMAN  Ribulose-phosphate 3-epimerase (Ribulose-5-phosphate-3-epimerase)
Length=228

 Score =  208 bits (530),  Expect = 1e-53, Method: Composition-based stats.
 Identities = 126/231 (54%), Positives = 165/231 (71%), Gaps = 11/231 (4%)

Query  6    IAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGD  65
            I PSIL SD ANLG EC +++++GAD+LH+DVMDGHFVPNIT G P+V SLR+ + +   
Sbjct  7    IGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQ---  63

Query  66   ASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKA  125
                      FFD HMMV  PE+WV   A  GA+Q+TFH EAT++P  L+K I+  G+K 
Sbjct  64   --------DPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKV  115

Query  126  ACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVD  185
              AIKPGTSV+ L   A  +DMALVMTVEPGFGGQKFMEDMMPKV  LR +FP L+I+VD
Sbjct  116  GLAIKPGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVD  175

Query  186  GGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRDL  236
            GG+G +T+ K A+AGAN+IV+G+++  + DP  VI+ ++   S+  + R L
Sbjct  176  GGVGPDTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSL  226


>gi|34924979|sp|Q8VEE0|RPE_MOUSE  Ribulose-phosphate 3-epimerase (Ribulose-5-phosphate-epimerase)
Length=228

 Score =  207 bits (526),  Expect = 4e-53, Method: Composition-based stats.
 Identities = 125/231 (54%), Positives = 165/231 (71%), Gaps = 11/231 (4%)

Query  6    IAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGD  65
            I PSIL SD ANLG EC +++++GAD+LH+DVMDGHFVPNIT G P+V SLR+ + +   
Sbjct  7    IGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQ---  63

Query  66   ASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKA  125
                      FFD HMMV  PE+WV   A  GA+Q+TFH EAT++P  L+K I+  G+K 
Sbjct  64   --------DPFFDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKV  115

Query  126  ACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVD  185
              AIKPGT+V+ L   A  +DMALVMTVEPGFGGQKFMEDMMPKV  LR +FP L+I+VD
Sbjct  116  GLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPTLDIEVD  175

Query  186  GGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRDL  236
            GG+G +T+ K A+AGAN+IV+G+++  + DP  VI+ ++   S+  + R L
Sbjct  176  GGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNVCSEAAQKRSL  226


>gi|75061668|sp|Q5R5Y2|RPE_PONPY  Ribulose-phosphate 3-epimerase (Ribulose-5-phosphate-3-epimerase)
Length=228

 Score =  205 bits (523),  Expect = 1e-52, Method: Composition-based stats.
 Identities = 125/231 (54%), Positives = 164/231 (70%), Gaps = 11/231 (4%)

Query  6    IAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGD  65
            I PSIL SD ANLG EC +++++GAD+LH+DVMDGHFVPNIT G P+V SLR+ + +   
Sbjct  7    IGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQ---  63

Query  66   ASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKA  125
                      FFD HMMV  PE+WV   A  GA+Q+ FH EAT++P  L+K I+  G+K 
Sbjct  64   --------DPFFDMHMMVSKPEQWVKPMAVAGANQYAFHLEATENPGALIKDIRENGMKV  115

Query  126  ACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVD  185
              AIKPGTSV+ L   A  +DMALVMTVEPGFGGQKFMEDMMPKV  LR +FP L+I+VD
Sbjct  116  GLAIKPGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVD  175

Query  186  GGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRDL  236
            GG+G +T+ K A+AGAN+IV+G+++  + DP  VI+ ++   S+  + R L
Sbjct  176  GGVGPDTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSL  226


>gi|11387063|sp|P57603|RPE_BUCAI  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=228

 Score =  204 bits (519),  Expect = 2e-52, Method: Composition-based stats.
 Identities = 90/240 (37%), Positives = 132/240 (55%), Gaps = 17/240 (7%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M K  +APSIL++DFA LG +  KVI+AG+D +H DVMD H+VPN+++G  I+ SLR   
Sbjct  1    MNKFFLAPSILSADFARLGEDIKKVIDAGSDLIHFDVMDNHYVPNLSMGPMILESLRN--  58

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
                         TA  D H+MV+  +  +  FAK GA   TFH EAT      + LIK 
Sbjct  59   ----------YNITAPIDVHLMVKPVDNLIPQFAKAGATFITFHPEATLHIERTLNLIKE  108

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--  178
             G KA  A  P T ++ L  +   LD+ L+M+V PGFG Q F+     K+  +R      
Sbjct  109  NGCKAGLAFNPATPLNFLDYILEKLDLILLMSVNPGFGNQSFLPSTFNKLREVRKIIDAN  168

Query  179  --HLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRDL  236
               + ++VDGG+  + I   A AGANV V G+ +F  ++   VI  +++++ +   SR +
Sbjct  169  FSDILLEVDGGVKLDNIADIACAGANVFVMGSGLFKYSNYKLVIEKIRKKL-EYAHSRSI  227


>gi|25091192|sp|Q8K940|RPE_BUCAP  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=228

 Score =  202 bits (515),  Expect = 7e-52, Method: Composition-based stats.
 Identities = 86/220 (39%), Positives = 124/220 (56%), Gaps = 16/220 (7%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M K  +A SIL++DFA LG +  K I+AG+DW+H DVMD H+VPN+T+G  I+ +LR   
Sbjct  1    MKKFFLASSILSADFARLGEDTKKAIDAGSDWIHFDVMDNHYVPNLTMGPMILKALRN--  58

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
                         T   D H+MV+  +  +  FA+ GAD  TFH E+T      + LIK 
Sbjct  59   ----------YNITVPIDVHLMVKPVDNLIPQFAEAGADFITFHPESTDHIDRTLNLIKE  108

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKF---  177
             G KA  A+ P TS++ L  +   LD+ L+M+V PGFG Q F+     K+  +R K    
Sbjct  109  CGCKAGLALNPATSLNFLDYVMEKLDLILLMSVNPGFGNQSFLPTSFNKLREVRKKIELN  168

Query  178  -PHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADP  216
              ++ ++VDGG+  E I + A +GANV V G+ +F   D 
Sbjct  169  SSNILLEVDGGVKLENISEVAFSGANVFVIGSGIFGYTDY  208


>gi|2829613|sp|P74061|RPE_SYNY3  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=230

 Score =  202 bits (513),  Expect = 1e-51, Method: Composition-based stats.
 Identities = 95/237 (40%), Positives = 133/237 (56%), Gaps = 20/237 (8%)

Query  1    MVKPII-APSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
            M K I+ APSIL++DF+ LG E   V  AGADW+H+DVMDG FVPNIT+G  IV ++R  
Sbjct  1    MSKNIVVAPSILSADFSRLGEEIKAVDEAGADWIHVDVMDGRFVPNITIGPLIVDAIRPL  60

Query  60   VPRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYE--ATQDPLHLVKL  117
                              D H+M+  PEK+V+DFAK GAD  + H E  A+      +  
Sbjct  61   T-------------KKTLDVHLMIVEPEKYVEDFAKAGADIISVHVEHNASPHLHRTLCQ  107

Query  118  IKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKF  177
            I+  G KA   + P T +D L  + P  D+ L+M+V PGFGGQ F+ +++PK+  LR   
Sbjct  108  IRELGKKAGAVLNPSTPLDFLEYVLPVCDLILIMSVNPGFGGQSFIPEVLPKIRALRQMC  167

Query  178  P----HLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKE  230
                    I+VDGGL      +  +AGAN IVAG++VF A +  + I+ ++     E
Sbjct  168  DERGLDPWIEVDGGLKPNNTWQVLEAGANAIVAGSAVFNAPNYAEAIAGVRNSKRPE  224


>gi|1169388|sp|P44756|RPE_HAEIN  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=224

 Score =  196 bits (499),  Expect = 5e-50, Method: Composition-based stats.
 Identities = 81/234 (34%), Positives = 130/234 (55%), Gaps = 16/234 (6%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M   +IAPSIL++D A LG +   V+NAGAD +H DVMD H+VPN+T G  +  +LR   
Sbjct  1    MKPYLIAPSILSADLARLGDDVQNVLNAGADVIHFDVMDNHYVPNLTFGPAVCQALRD--  58

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
                         TA  D H+MV+  ++ + DFAK GA+  TFH E+++     ++LI+ 
Sbjct  59   ----------YGITAPIDVHLMVKPVDRIIPDFAKAGANYITFHPESSEHIDRSLQLIRD  108

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--  178
             G K+     P   +  L  +   +D+ L+M+V PGFGGQ F+   + K++  R      
Sbjct  109  CGCKSGLVFNPAMPLSYLDYVLDKVDVVLLMSVNPGFGGQSFIPATLKKLQQARKIIDES  168

Query  179  --HLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKE  230
               + ++VDGG+  + I + A AGA++ VAG+++F   D   VI  ++ +++  
Sbjct  169  GYDIRLEVDGGVKVDNIAEIAAAGADMFVAGSAIFGKPDYKQVIDQIRTQLASV  222


>gi|2499728|sp|Q43843|RPE_SOLTU  Ribulose-phosphate 3-epimerase, chloroplast precursor (Pentose-5-phosphate 
3-epimerase) (PPE) (RPE) (R5P3E)
Length=280

 Score =  195 bits (497),  Expect = 1e-49, Method: Composition-based stats.
 Identities = 88/235 (37%), Positives = 129/235 (54%), Gaps = 19/235 (8%)

Query  5    IIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPG  64
            I++PSIL+++F+ LG +   +  AG DW+H+DVMDG FVPNIT+G  +V SLR     P 
Sbjct  58   IVSPSILSANFSKLGEQVKAIEQAGCDWIHVDVMDGRFVPNITIGPLVVDSLRPITDLP-  116

Query  65   DASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQ--DPLHLVKLIKSKG  122
                         D H+M+  P++ V DF K GAD  + H E +        +  IKS G
Sbjct  117  ------------LDVHLMIVEPDQRVPDFIKAGADIVSVHCEQSSTIHLHRTINQIKSLG  164

Query  123  IKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP----  178
             KA   + PGT +  +  +   +D+ L+M+V PGFGGQ F+E  + K+  LR        
Sbjct  165  AKAGVVLNPGTPLTAIEYVLDAVDLVLIMSVNPGFGGQSFIESQVKKISDLRKICAERGL  224

Query  179  HLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRS  233
            +  I+VDGG+G +   K  +AGAN +VAG++VF A D  + I  +K     E  +
Sbjct  225  NPWIEVDGGVGPKNAYKVIEAGANALVAGSAVFGAPDYAEAIKGIKTSKRPEAVA  279


>gi|2833386|sp|Q43157|RPE_SPIOL  Ribulose-phosphate 3-epimerase, chloroplast precursor (Pentose-5-phosphate 
3-epimerase) (PPE) (RPE) (R5P3E)
Length=285

 Score =  195 bits (496),  Expect = 1e-49, Method: Composition-based stats.
 Identities = 91/232 (39%), Positives = 127/232 (54%), Gaps = 19/232 (8%)

Query  5    IIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPG  64
            I++PSIL+++FA LG +   V  AG DW+H+DVMDG FVPNIT+G  +V +LR     P 
Sbjct  63   IVSPSILSANFAKLGEQVKAVELAGCDWIHVDVMDGRFVPNITIGPLVVDALRPVTDLP-  121

Query  65   DASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYE--ATQDPLHLVKLIKSKG  122
                         D H+M+  PE+ V DF K GAD  + H E  +T      V  IKS G
Sbjct  122  ------------LDVHLMIVEPEQRVPDFIKAGADIVSVHCELASTIHLHRTVNQIKSLG  169

Query  123  IKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAK----FP  178
             KA   + PGT +  +  +   +D+ L+M+V PGFGGQ F+E  + K+  LR        
Sbjct  170  AKAGVVLNPGTPLSTIEYVLDVVDLVLIMSVNPGFGGQSFIESQVKKISDLRKMCVEKGV  229

Query  179  HLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKE  230
            +  I+VDGG+      K  +AGAN +VAG++VF A D  + I  +K     E
Sbjct  230  NPWIEVDGGVTPANAYKVIEAGANALVAGSAVFGAKDYAEAIKGIKASKRPE  281


>gi|84028110|sp|P0AG09|RPE_ECO57  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
 gi|84028150|sp|P0AG08|RPE_ECOL6  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
 gi|84028157|sp|P0AG07|RPE_ECOLI  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
 gi|84028158|sp|P0AG10|RPE_SHIFL  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=225

 Score =  194 bits (494),  Expect = 2e-49, Method: Composition-based stats.
 Identities = 90/234 (38%), Positives = 133/234 (56%), Gaps = 16/234 (6%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M + +IAPSIL++DFA LG +  K + AGAD +H DVMD H+VPN+T+G  ++ SLR   
Sbjct  1    MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRN--  58

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
                         TA  D H+MV+  ++ V DFA  GA   TFH EA++     ++LIK 
Sbjct  59   ----------YGITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRTLQLIKE  108

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--  178
             G KA     P T +  L  +   LD+ L+M+V PGFGGQ F+   + K+  +R +    
Sbjct  109  NGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLREVRRRIDES  168

Query  179  --HLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKE  230
               + ++VDGG+    I + A AGA++ VAG+++F   D   VI  M+ E++K 
Sbjct  169  GFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDEMRSELAKV  222


>gi|51701874|sp|O14105|RPE_SCHPO  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (RPE)
Length=228

 Score =  192 bits (487),  Expect = 1e-48, Method: Composition-based stats.
 Identities = 115/235 (48%), Positives = 151/235 (64%), Gaps = 10/235 (4%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            MV+  IAPS+LA DFANL  E  +++  G+DWLH+DVMD  FVPN+T+G  +V ++R   
Sbjct  1    MVQAKIAPSLLAGDFANLEKEVGRMLKYGSDWLHVDVMDAQFVPNLTIGPIVVKAMRNHY  60

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
                       K  AFFDCH+MV  PE+++D  A  GA  F FHYEAT+    ++     
Sbjct  61   T----------KEEAFFDCHLMVIEPERYIDQLADAGASLFCFHYEATEKHEEIISRAHE  110

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHL  180
            KG+   CA+KP T V+V+      LDM LVMTVEPG GGQ FM + +PKVE LR K+P L
Sbjct  111  KGMLVGCALKPKTPVEVILPFVEKLDMVLVMTVEPGKGGQSFMPECLPKVEFLRKKYPTL  170

Query  181  NIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRD  235
            N++VDGGL  +T+  AA AGANVIVAGT+VF A  P +VIS ++  V K   ++ 
Sbjct  171  NVEVDGGLSLKTVDAAADAGANVIVAGTAVFHAQSPEEVISGLRNSVMKAQETKP  225


>gi|1169389|sp|P45455|RPE_SERMA  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=210

 Score =  188 bits (477),  Expect = 2e-47, Method: Composition-based stats.
 Identities = 83/222 (37%), Positives = 123/222 (55%), Gaps = 16/222 (7%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M K +IAPSIL++DFA LG +   V+ AG D +H DVMD H+VPN+T+G  +  +LR   
Sbjct  1    MKKFLIAPSILSADFARLGEDTANVLAAGGDVVHFDVMDNHYVPNLTIGPMVCEALRN--  58

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
                         TA  D H+MV+  ++ V DFAK GA   +FH EA++     ++LIK 
Sbjct  59   ----------YGITAPIDVHLMVKPVDRIVPDFAKAGASYISFHPEASEHVDRTIQLIKE  108

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHL  180
             G KA     P T +  L  +   +D+ L+M+V PGFGGQ F+   + K+  +R      
Sbjct  109  HGCKAGLVFNPATPLSYLDYVMDKIDVILLMSVNPGFGGQSFIHGTLDKLRQVRKLIDDS  168

Query  181  N----IQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHD  218
                 ++VDGG+  + I + A AGA++ VAG+++F   D   
Sbjct  169  GRDIRLEVDGGVKVDNIAEIAAAGADMFVAGSAIFGQPDYRK  210


>gi|6226024|sp|O67098|RPE_AQUAE  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=222

 Score =  187 bits (475),  Expect = 3e-47, Method: Composition-based stats.
 Identities = 82/232 (35%), Positives = 125/232 (53%), Gaps = 17/232 (7%)

Query  4    PIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
             ++APSILA D+  +G +    I  GAD LH DVMDGHFVPNIT G  I++ +R+    P
Sbjct  2    KLLAPSILAGDWWCIGEQIQATIRGGADILHYDVMDGHFVPNITAGYEILSHIRKRASLP  61

Query  64   GDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGI  123
                          D H+M+ENP+K++  F + GA+  + H E        ++LIK  G 
Sbjct  62   -------------IDAHLMIENPDKYIPKFVEAGANWISVHIENNYHIHRTLQLIKELGA  108

Query  124  KAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAK----FPH  179
            KA   + PGTS+  + E   + D  L+M+V PGF GQKF+E  + ++  L+       P 
Sbjct  109  KAGVVVNPGTSLSAIEEALYYADYVLLMSVNPGFSGQKFIERSIERLRILKEMRDRINPS  168

Query  180  LNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKEL  231
              I++DGG+ +  I +  +AGA+V+V G+ +F A D       +K  +   +
Sbjct  169  CLIEIDGGIKENNIAEVVRAGADVVVVGSGIFGAKDIEAQTRKLKSLMLSAV  220


>gi|60390595|sp|Q9SE42|RPE1_ORYSA  Ribulose-phosphate 3-epimerase, cytoplasmic isoform (Ribulose-5-phosphate-epimerase) 
(Cyt-RPEase) (RPEcyt) (Pentose-5-phosphate 
3-epimerase) (PPE)
Length=228

 Score =  187 bits (475),  Expect = 4e-47, Method: Composition-based stats.
 Identities = 115/234 (49%), Positives = 161/234 (68%), Gaps = 18/234 (7%)

Query  6    IAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGD  65
            IAPS+L+SDFANL  E  +++  GADWLH+D+MDGHFVPN+T+G P++ SLR+       
Sbjct  9    IAPSMLSSDFANLAAEADRMVRLGADWLHMDIMDGHFVPNLTIGAPVIQSLRKHT-----  63

Query  66   ASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDP-LHLVKLIKSKGIK  124
                     A+ DCH+MV NP  +V+  AK GA  FTFH E ++D    L++ IK+KG++
Sbjct  64   --------KAYLDCHLMVTNPSDYVEPLAKAGASGFTFHIEVSRDNWQELIQSIKAKGMR  115

Query  125  AACAIKPGTSVDVLFELAPH---LDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLN  181
               +++PGT V+ +F L      +++ LVMTVEPGFGGQKFM +MM KV  LR K+P L+
Sbjct  116  PGVSLRPGTPVEEVFPLVEAENPVELVLVMTVEPGFGGQKFMPEMMEKVRALRKKYPSLD  175

Query  182  IQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRD  235
            I+VDGGLG  TI  AA AGAN IVAG+S+F AA+P +VIS +++ V +  +++ 
Sbjct  176  IEVDGGLGPSTIDVAASAGANCIVAGSSIFGAAEPGEVISALRKSV-EGSQNKS  228


>gi|6647758|sp|O34557|RPE_BACSU  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=217

 Score =  186 bits (474),  Expect = 4e-47, Method: Composition-based stats.
 Identities = 97/229 (42%), Positives = 139/229 (60%), Gaps = 20/229 (8%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M+K  +APSIL++DFA LG E   V   GAD +HIDVMDGHFVPNIT+G  IV ++R   
Sbjct  1    MIK--VAPSILSADFAALGNEIKDVEKGGADCIHIDVMDGHFVPNITIGPLIVEAVRPVT  58

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
              P              D H+M+E P++++  FAK GAD  + H EA       ++LIK 
Sbjct  59   DLP-------------LDVHLMIEEPDRYIPAFAKAGADILSVHAEACPHLHRTIQLIKE  105

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--  178
            +G+KA   + P T V V+  +   LD+ L+MTV PGFGGQKF+  ++PK++ ++      
Sbjct  106  QGVKAGVVLNPHTPVQVIEHVFDDLDLVLLMTVNPGFGGQKFIHSVLPKIKEVKRMADEK  165

Query  179  ---HLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMK  224
                L I+VDGG+ KET P   +AGAN++VAG++V+  +D    IS ++
Sbjct  166  GKKDLLIEVDGGVNKETAPLVIEAGANLLVAGSAVYGQSDRKKAISEIR  214


>gi|109940150|sp|Q9ZTP5|RPE_ORYSA  Ribulose-phosphate 3-epimerase, chloroplast precursor (Pentose-5-phosphate 
3-epimerase) (PPE) (RPE) (R5P3E)
Length=274

 Score =  185 bits (469),  Expect = 1e-46, Method: Composition-based stats.
 Identities = 89/228 (39%), Positives = 126/228 (55%), Gaps = 19/228 (8%)

Query  5    IIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPG  64
            I++PSIL+++F+ LG +   V  AG DW+H+DVMDG FVPNIT+G  +V +LR     P 
Sbjct  52   IVSPSILSANFSKLGEQVKAVEVAGCDWIHVDVMDGRFVPNITIGPLVVDALRPVTDLP-  110

Query  65   DASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQ--DPLHLVKLIKSKG  122
                         D H+M+  PE+ V DF K GAD  + H E +        V  IKS G
Sbjct  111  ------------LDVHLMIVEPEQRVPDFIKAGADIVSVHCEQSSTIHLHRTVNQIKSLG  158

Query  123  IKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP----  178
             KA   + P T +  +  +   +D+ L+M+V PGFGGQ F+E  + K+  LR        
Sbjct  159  AKAGVVLNPATPLTAIDYVLDVVDLVLIMSVNPGFGGQSFIESQVKKIAELRRLCAEKGV  218

Query  179  HLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
            +  I+VDGG+G +   K  +AGAN IVAG++VF A D  + I  +K  
Sbjct  219  NPWIEVDGGVGPKNAYKVIEAGANAIVAGSAVFGAPDYAEAIKGIKTS  266


>gi|6226025|sp|Q9Z8Z9|RPE_CHLPN  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=229

 Score =  180 bits (458),  Expect = 3e-45, Method: Composition-based stats.
 Identities = 76/226 (33%), Positives = 123/226 (54%), Gaps = 22/226 (9%)

Query  1    MVKP---IIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLR  57
            M K    ++ PSI+ +D   LG E  K+  AG+D++HID+MDGHFVPN+T G  I+ ++ 
Sbjct  1    MKKQESVLVGPSIMGADLTCLGVEAKKLEQAGSDFIHIDIMDGHFVPNLTFGPGIIAAIN  60

Query  58   RSVPRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKL  117
            RS                F + H M+ NP ++++ F + GAD+   H+EA++D   L+  
Sbjct  61   RSTDL-------------FLEVHAMIYNPFEFIESFVRSGADRIIVHFEASEDIKELLSY  107

Query  118  IKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKF  177
            IK  G++A  A  P TS++ L    P  D+ ++M+V PGF GQ F+ + + K+   R   
Sbjct  108  IKKCGVQAGLAFSPDTSIEFLPSFLPFCDVVVLMSVYPGFTGQSFLPNTIEKIAFARHAI  167

Query  178  ------PHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPH  217
                      I+VDGG+ +++ P    AGA+++V  + +F A    
Sbjct  168  KTLGLKDSCLIEVDGGIDQQSAPLCRDAGADILVTASYLFEADSLA  213


>gi|46396626|sp|Q89A59|RPE_BUCBP  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=228

 Score =  180 bits (458),  Expect = 3e-45, Method: Composition-based stats.
 Identities = 72/232 (31%), Positives = 126/232 (54%), Gaps = 14/232 (6%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M K +++ S+L+++F+ LG +   V+ +G+D +H DVMD H+V N+T G  ++ SLR   
Sbjct  1    MKKFLLSSSVLSANFSRLGEDIFDVLKSGSDMIHYDVMDNHYVKNLTFGPIVLESLR---  57

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
                   + EK  +   D H+M    +  +  FAK   +  +FH E+T +    +KLIKS
Sbjct  58   -------SVEKIKSMVIDVHLMTCPVDDLIIKFAKLDVNIISFHPESTNNVEKTIKLIKS  110

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--  178
             G K   A+ P T + VL  +   +D+ L+M+V PGF GQKF+  ++ K+  +R      
Sbjct  111  YGCKVGLALNPLTPLCVLDNVLDKIDLILLMSVNPGFPGQKFIPSILNKIRIVRELIDKS  170

Query  179  --HLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVS  228
              ++ ++VDGG+    I K A  G ++ V G+++F + +    I   ++ + 
Sbjct  171  KKNILLEVDGGINLSNIFKIASFGTDIFVIGSAIFNSINYDLTIRSFRDVLK  222


>gi|729236|sp|Q04539|RPEP_RALEH  Ribulose-phosphate 3-epimerase, plasmid (Pentose-5-phosphate 
3-epimerase) (PPE) (R5P3E)
Length=241

 Score =  175 bits (445),  Expect = 1e-43, Method: Composition-based stats.
 Identities = 80/235 (34%), Positives = 123/235 (52%), Gaps = 21/235 (8%)

Query  5    IIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPG  64
             +APSIL++DFA LG E   +   GAD +H DVMD H+V N+T+G  +  ++R  V  P 
Sbjct  17   RLAPSILSADFARLGEEVCAIEAGGADLVHFDVMDNHYVSNLTIGPLVCEAIRPLVSIP-  75

Query  65   DASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIK  124
                         D H+MVE  +  +  FAK GA+  +FH EA++     + LI+  G K
Sbjct  76   ------------IDVHLMVEPVDALIPMFAKAGANLISFHPEASRHVDRTIGLIRDHGCK  123

Query  125  AACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPH-----  179
            A   + P T +  L      LD+ L+M+V PGFGGQ F+  ++ KV   RA+        
Sbjct  124  AGLVLNPATPLSWLDHTLDKLDLVLLMSVNPGFGGQAFIPGVLDKVRQARARIDRQVAAG  183

Query  180  ---LNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKEL  231
               + +++DGG+  + I + A+AGA+  VAG++VF A D       +   + +  
Sbjct  184  GRPVWLEIDGGVKADNITEIARAGADTFVAGSAVFGAPDADGGYRGILHRLREAA  238


>gi|729235|sp|P40117|RPEC_RALEH  Ribulose-phosphate 3-epimerase, chromosomal (Pentose-5-phosphate 
3-epimerase) (PPE) (R5P3E)
Length=241

 Score =  175 bits (444),  Expect = 1e-43, Method: Composition-based stats.
 Identities = 82/235 (34%), Positives = 124/235 (52%), Gaps = 21/235 (8%)

Query  5    IIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPG  64
             +APSIL++DFA LG E   +   GAD +H DVMD H+VPN+T+G  +  ++R  V  P 
Sbjct  17   RLAPSILSADFARLGEEVCAIEAGGADLVHFDVMDNHYVPNLTIGPLVCEAIRPLVSIP-  75

Query  65   DASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIK  124
                         D H+MVE  +  +  FAK GA+  +FH EA++     + LI+  G K
Sbjct  76   ------------IDVHLMVEPVDALIPLFAKAGANIISFHPEASRHVDRTIGLIRDHGCK  123

Query  125  AACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPH-----  179
            A   + P T +  L      LD+ L+M+V PGFGGQ F+  ++ KV   RA+        
Sbjct  124  AGLVLNPATPLGWLDHTLDQLDLVLLMSVNPGFGGQAFIPGVLDKVRQARARIDRQVDAG  183

Query  180  ---LNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKEL  231
               + +++DGG+  + I   A+AGA+  VAG++VF A D     S +   + +  
Sbjct  184  GRPVWLEIDGGVKADNIAAIARAGADTFVAGSAVFGAPDADGGYSSILYRLREAA  238


>gi|73622033|sp|Q82WI1|TRPA_NITEU  Tryptophan synthase alpha chain
Length=275

 Score =  175 bits (444),  Expect = 1e-43, Method: Composition-based stats.
 Identities = 43/257 (16%), Positives = 85/257 (33%), Gaps = 27/257 (10%)

Query  2    VKPIIAPSILASDFANLGCEC--HKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +  + P I A D          H++  AG D + + V    F   +  G  I  S  R+
Sbjct  15   NRAALIPFITAGDPDATTTVALMHRLTQAGVDLIELGV---PFSDPMADGPTIQRSSERA  71

Query  60   VPRPGDASNTEKKPTAF------FDCHMM-VENPE------KWVDDFAKCGADQFTFHYE  106
            +       +       F          +M   NP        +V      G D       
Sbjct  72   LKHHISLKDVFSMVAEFRKTNQSTPVVLMGYANPIEAMGYKDFVQTAGHAGVDGVLVVDY  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFME--  164
              ++    V+ +K + I     + P T    +  +A      +      G  G   ++  
Sbjct  132  PPEECTEWVRYLKEQNIDPIFLLSPTTPESRIRRVAELARGYVYYVSLKGVTGASHLDLH  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT------AADPHD  218
            ++  K+  LR+   ++ I V  G+  E   +     A+ +V G+ +        AAD   
Sbjct  192  EVGDKLSQLRSYI-NIPIGVGFGIRDEQTARRIAEQADAVVIGSRIVEEIEHSPAADLLA  250

Query  219  VISFMKEEVSKELRSRD  235
             +  + E + + + ++ 
Sbjct  251  NVGALVESLRRAIDAKS  267


>gi|14195180|sp|Q9PKR7|RPE_CHLMU  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=228

 Score =  173 bits (440),  Expect = 3e-43, Method: Composition-based stats.
 Identities = 78/224 (34%), Positives = 122/224 (54%), Gaps = 21/224 (9%)

Query  1    MVKP--IIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRR  58
            M K   +IAPSI+ +D A LG     +  +GA+ +HIDVMDGHFVPNIT G  I+ ++ R
Sbjct  1    MKKQGVLIAPSIMGADLACLGDAARNIEESGANLIHIDVMDGHFVPNITFGPGIIAAINR  60

Query  59   SVPRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLI  118
            S                F + H M+  P ++V+ F K GAD+   H+EA ++   ++  I
Sbjct  61   STDL-------------FLEVHAMIYTPFEFVEAFVKAGADRIIVHFEAAENLKEILDYI  107

Query  119  KSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKF-  177
            +  G++A  A  P TS++ +    P  D+ L+M+V+PGF GQKF+ D + K+  +R    
Sbjct  108  RKCGVQAGIAFSPETSIEFISAFIPLCDVILLMSVQPGFCGQKFIPDTIEKIRFVRQAIQ  167

Query  178  -----PHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADP  216
                     I+VDGG+ +E+     +AGA+++VA +  F     
Sbjct  168  TLGKEGSCLIEVDGGIDEESARACREAGADILVAASYFFKKDSI  211


>gi|18203210|sp|Q9L0Z5|RPE_STRCO  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=228

 Score =  172 bits (436),  Expect = 1e-42, Method: Composition-based stats.
 Identities = 99/229 (43%), Positives = 140/229 (61%), Gaps = 19/229 (8%)

Query  6    IAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGD  65
            I PSIL++DFA L  E   V   GADWLH+DVMD HFVPN+TLG P+V SL R+      
Sbjct  5    INPSILSADFARLADEAKAVE--GADWLHVDVMDNHFVPNLTLGVPVVESLARATD----  58

Query  66   ASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKA  125
                        DCH+M+E P++W   + + GA   TFH EA   P+ L + I++KG +A
Sbjct  59   ---------TPLDCHLMIEAPDRWAPQYVEAGAGSVTFHAEAAAAPVRLAREIRAKGARA  109

Query  126  ACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVET----LRAKFPHLN  181
            + A+KP T V+   +L P LDM L+MTVEPGFGGQ F++ M+PK+      ++     L 
Sbjct  110  SMALKPATPVEPYEDLLPELDMLLIMTVEPGFGGQAFLDIMLPKIRRTRELIKKHGLELW  169

Query  182  IQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKE  230
            +QVDGG+   TI + A AGA+V VAG++V+ A+DP + +  ++ +    
Sbjct  170  LQVDGGVSAATIERCADAGADVFVAGSAVYGASDPAEAVRALRTQADAA  218


>gi|54039256|sp|P65761|RPE_MYCBO  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
 gi|54041952|sp|P65760|RPE_MYCTU  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=229

 Score =  171 bits (435),  Expect = 1e-42, Method: Composition-based stats.
 Identities = 96/231 (41%), Positives = 145/231 (62%), Gaps = 19/231 (8%)

Query  4    PIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            P+IAPSILA+DFA L  E   V   GADWLH+DVMDGHFVPN+T+G P+V SL      P
Sbjct  8    PLIAPSILAADFARLADEAAAV--NGADWLHVDVMDGHFVPNLTIGLPVVESLLAVTDIP  65

Query  64   GDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGI  123
                          DCH+M++NP++W   +A+ GA   TFH EAT +P+ + + I++ G 
Sbjct  66   -------------MDCHLMIDNPDRWAPPYAEAGAYNVTFHAEATDNPVGVARDIRAAGA  112

Query  124  KAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP----H  179
            KA  ++KPGT ++   ++ PH D  LVM+VEPGFGGQ+F+ +++ KV  +R         
Sbjct  113  KAGISVKPGTPLEPYLDILPHFDTLLVMSVEPGFGGQRFIPEVLSKVRAVRKMVDAGELT  172

Query  180  LNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKE  230
            + +++DGG+  +TI +AA+AG +  VAG++V+ A DP   ++ ++ +    
Sbjct  173  ILVEIDGGINDDTIEQAAEAGVDCFVAGSAVYGADDPAAAVAALRRQAGAA  223


>gi|73622040|sp|Q7TUC8|TRPA_PROMP  Tryptophan synthase alpha chain
Length=279

 Score =  170 bits (432),  Expect = 3e-42, Method: Composition-based stats.
 Identities = 42/252 (16%), Positives = 85/252 (33%), Gaps = 25/252 (9%)

Query  3    KPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K  + P I+A D           K+   GAD + + +    +   +  G  I  S  R++
Sbjct  30   KLALMPFIMAGDPNIETTSEILLKLQEKGADLIELGI---PYSDPLADGPIIQLSASRAL  86

Query  61   PRPGDASNTEK-----KPTAFFDCHM-MVENP------EKWVDDFAKCGADQFTFHYEAT  108
                   N  +     K        +    NP      E + +  +K G           
Sbjct  87   KSGTTLKNVIQLLESLKDKLHIPIILFTYFNPVLNFGLENFCELASKVGVSGLIIPDLPL  146

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK-FMEDMM  167
            ++     ++I S  I     + P T  + +  ++ +      +    G  G++  ME+ +
Sbjct  147  EEAYKFSEIISSYSIDLILLVAPTTPSERMKIISNNTKGFTYLVSVTGVTGERNKMENRV  206

Query  168  PKVETLRAKFPHLNIQVDGGL-GKETIPKAAKAGANVIVAGTSVFT------AADPHDVI  220
              + T   +     + V  G+   E + K  K GA+ ++ G++           +  + I
Sbjct  207  ENLITKLQEISINPVAVGFGISSPEHVNKVRKWGADGVIIGSAFVKRISNSNEKEVVNQI  266

Query  221  SFMKEEVSKELR  232
                EE+ K   
Sbjct  267  GKFCEEMRKAAD  278


>gi|6226026|sp|O84123|RPE_CHLTR  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=233

 Score =  170 bits (432),  Expect = 3e-42, Method: Composition-based stats.
 Identities = 77/224 (34%), Positives = 123/224 (54%), Gaps = 21/224 (9%)

Query  1    MVKP--IIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRR  58
            M K   ++APSI+ +D A +G E   +  +GAD +HIDVMDGHFVPNIT G  +V ++ R
Sbjct  6    MKKQGVLVAPSIMGADLACIGREARNIEESGADLIHIDVMDGHFVPNITFGPGVVAAINR  65

Query  59   SVPRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLI  118
            S                F + H M+  P ++V+ F K GAD+   H+EA ++   ++  I
Sbjct  66   STEL-------------FLEVHAMIYTPFEFVEAFVKAGADRIIVHFEAAENIKEIISYI  112

Query  119  KSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKF-  177
            +  G++A  A  P TS++ +    P  D+ L+M+V PGF GQKF+ D + +++ ++    
Sbjct  113  QKCGVQAGVAFSPETSIEFVTSFIPLCDVILLMSVHPGFCGQKFIPDTIERIQFVKQAIQ  172

Query  178  -----PHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADP  216
                     I+VDGG+ KE+     +AGA+++VA +  F     
Sbjct  173  VLGREGSCLIEVDGGIDKESARACREAGADILVAASYFFEKDSI  216


>gi|6647760|sp|Q9ZJ75|RPE_HELPJ  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=217

 Score =  169 bits (429),  Expect = 7e-42, Method: Composition-based stats.
 Identities = 76/229 (33%), Positives = 122/229 (53%), Gaps = 22/229 (9%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M    +APS+L++DF +L  E   V N  AD+LH+DVMDGH+VPN+T+G  I        
Sbjct  1    MK---VAPSLLSADFMHLAKEIESVSN--ADFLHVDVMDGHYVPNLTMGPVI--------  47

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
                   N  +      D H+MVEN   +V+ FA       + H E  + P  +++LIKS
Sbjct  48   -----LENVTQMSQVPLDVHLMVENASFFVELFAPLNPQIISIHAENEKHPHRVLQLIKS  102

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKV----ETLRAK  176
             GI     + P T  + +  L   + + L+M+V PGFGGQKF++ ++ K     E ++  
Sbjct  103  SGITPGIVLNPHTHEESIKYLLESVGLVLLMSVNPGFGGQKFLDLVLEKCLKVKELIKRY  162

Query  177  FPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKE  225
             P   ++VDGG+  + I +  +AG +V+V+G+ +F + D    I  ++ 
Sbjct  163  NPSCLLEVDGGVNDKNIFELQQAGVDVVVSGSYIFESKDRKLAIEGLQN  211


>gi|2829457|sp|P56188|RPE_HELPY  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=217

 Score =  167 bits (423),  Expect = 3e-41, Method: Composition-based stats.
 Identities = 73/229 (31%), Positives = 121/229 (52%), Gaps = 22/229 (9%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M    +APS+L++DF +L  E   V N  AD+LH+DVMDGH+VPN+T+G  +        
Sbjct  1    MK---VAPSLLSADFMHLAKEIESVSN--ADFLHVDVMDGHYVPNLTMGPVV--------  47

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
                   N  +      D H+MVEN   + + FA       + H E  + P  +++LIK+
Sbjct  48   -----LENVTQMSQVPLDVHLMVENASFFAELFAPLKPQIISIHAENEKHPHRVLQLIKN  102

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKV----ETLRAK  176
             GI     + P T  + +  L   + + L+M+V PGFGGQKF++ ++ K     E ++  
Sbjct  103  LGITPGIVLNPHTHEESIKYLLESVGLVLLMSVNPGFGGQKFLDLVLEKCLKVKELIKRY  162

Query  177  FPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKE  225
             P   ++VDGG+  + I +  +AG +V+V+G+ +F + D    I  ++ 
Sbjct  163  NPSCLLEVDGGVNDKNIFELQQAGVDVVVSGSYIFKSKDRKLAIEGLQN  211


>gi|73622054|sp|Q5N324|TRPA_SYNP6  Tryptophan synthase alpha chain
Length=266

 Score =  166 bits (421),  Expect = 5e-41, Method: Composition-based stats.
 Identities = 38/252 (15%), Positives = 84/252 (33%), Gaps = 25/252 (9%)

Query  6    IAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            + P + A D            +   GAD + + V    +   +  G  I  +  R++   
Sbjct  19   LIPFLTAGDPDLETTRQALLALDREGADLIELGV---PYSDPLADGPVIQAAATRALQAG  75

Query  64   GDASNTEK-------KPTAFFDCHMMVENP------EKWVDDFAKCGADQFTFHYEATQD  110
                +          +  A         NP      E ++D  A  GA+         ++
Sbjct  76   TRLDDVLALLKDVRSQIKAPI-VLFTYCNPILNRGFEAFLDQIAAAGANGLVVPDLPLEE  134

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG--GQKFMEDMMP  168
               L ++   +GI     I P +S D +  ++      + +    G     Q     +  
Sbjct  135  SQRLSEVAAERGIDLILLIAPTSSADRIAAISKQARGFIYLVSVTGVTGMRQGMQSRVAD  194

Query  169  KVETLRAKFPHLNIQVDGGL-GKETIPKAAKAGANVIVAGTSVFT--AADPHDVISFMKE  225
             ++ +R       I V  G+ G E   +    GA+ ++ G++          + ++ +  
Sbjct  195  LLQEIRQ-GTDKPIGVGFGISGAEQARQVRDWGADGVIVGSAFVNRLQEQGVEGVATLCR  253

Query  226  EVSKELRSRDLL  237
            E+ + +  + +L
Sbjct  254  ELRQAIDRQPVL  265


>gi|2833527|sp|Q58093|RPE_METJA  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=234

 Score =  166 bits (420),  Expect = 9e-41, Method: Composition-based stats.
 Identities = 89/241 (36%), Positives = 132/241 (54%), Gaps = 22/241 (9%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M+K  I  SIL++DF +L  E  K   AG D+ H+D+MDGHFVPNI++G  I   +++  
Sbjct  1    MIK--IGASILSADFGHLREEIKKAEEAGVDFFHVDMMDGHFVPNISMGIGIAKHVKKLT  58

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
              P              + H+MVEN + +V++F +   D  TFH EA + P  ++  IKS
Sbjct  59   ELP-------------VEVHLMVENVDLFVNEFEEM--DYITFHIEAVKFPFRIINRIKS  103

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKF---  177
             G K   A+ P T +D +  +   +   LVMTVEPGF GQKF+  M  K+  L++     
Sbjct  104  IGAKPIVALNPATPLDAIEYILGDVYAVLVMTVEPGFSGQKFIPVMTKKIRKLKSMIVEN  163

Query  178  -PHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRDL  236
                 I VDGG+  ET P A KAGA+V+VA +++F   D    +  ++E   + L ++D 
Sbjct  164  GYDTKIFVDGGINVETAPLAVKAGADVLVAASAIFGKDDVKTAVKNLREAALEAL-NKDF  222

Query  237  L  237
            L
Sbjct  223  L  223


>gi|6094119|sp|P51012|RPE_RHOCA  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=228

 Score =  164 bits (415),  Expect = 3e-40, Method: Composition-based stats.
 Identities = 85/209 (40%), Positives = 119/209 (56%), Gaps = 16/209 (7%)

Query  6    IAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGD  65
            IAPSIL++DFA+ G E   +   GADW+H+DVMDGHFVPN+T G P V + R+       
Sbjct  9    IAPSILSADFADFGREIQAIEAQGADWVHVDVMDGHFVPNLTFGPPAVAAFRKH------  62

Query  66   ASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKA  125
                        D H+M+   + ++D +A+ GAD  T H EA       ++ I++ G+K+
Sbjct  63   -------VKTVMDVHLMISPVDAYIDAYAQAGADVLTAHVEAGPHIHRTLQAIRAAGMKS  115

Query  126  ACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLN--IQ  183
              AI PGT  + +  +    D+  VMTV PGFGGQK+++ M  KV  LRA        I+
Sbjct  116  GVAINPGTPAEAIEHVLDIADVVCVMTVNPGFGGQKYID-MTAKVRKLRAMIGDRPVHIE  174

Query  184  VDGGLGKETIPKAAKAGANVIVAGTSVFT  212
            +DGG+   T P  A AGA+V VAG+ VF 
Sbjct  175  IDGGMDPVTAPLMAAAGADVFVAGSGVFK  203


>gi|73622039|sp|Q7TV26|TRPA_PROMM  Tryptophan synthase alpha chain
Length=275

 Score =  163 bits (413),  Expect = 5e-40, Method: Composition-based stats.
 Identities = 37/251 (14%), Positives = 84/251 (33%), Gaps = 25/251 (9%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  + P ++A D            +  +GAD + + +    +   +  G  I  +  R++
Sbjct  27   RLALMPFLMAGDPDLETTAEVLLSLEQSGADMIELGI---PYSDPLADGPVIQAAASRAL  83

Query  61   PRPGDASNTEKKP-----TAFFDCHM-MVENP------EKWVDDFAKCGADQFTFHYEAT  108
                  +   +              +    NP      E++ D+ A+ G           
Sbjct  84   ASGTTPARVLQMLIDLRGKLSIPVILFTYTNPLFNRGMERFCDEAAEAGVAGLVVPDLPL  143

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF-MEDMM  167
            ++   L  L  ++G+     + P T  + +  +A        +    G  G++  MED +
Sbjct  144  EEAERLSPLASARGLDLVLLVAPTTPAERMARIAESSRGFTYLVSVTGVTGERSVMEDRV  203

Query  168  PKVETLRAKFPHLNIQVDGGL-GKETIPKAAKAGANVIVAGTSVFT---AADPHDVISF-  222
              +           + V  G+ G + + +    GA+  + G+++     AA P  V    
Sbjct  204  QSLVQQLKLSGSNPVAVGFGISGPQQVRQVRSWGADGAIVGSALVKRMAAAAPGLVAQEA  263

Query  223  --MKEEVSKEL  231
                +E+    
Sbjct  264  GLFCKELRNAA  274


>gi|6647759|sp|O66107|RPE_TREPA  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=218

 Score =  163 bits (413),  Expect = 5e-40, Method: Composition-based stats.
 Identities = 82/213 (38%), Positives = 117/213 (54%), Gaps = 17/213 (7%)

Query  4    PIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
              +APS+L++DF+ L      +   GA W+H+DVMDGHFVPN+T G P++  LR     P
Sbjct  5    FTLAPSLLSADFSALDRALVYLEAHGAQWVHLDVMDGHFVPNLTFGAPVLRCLRSKTHLP  64

Query  64   GDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGI  123
                          D H+MV  P   ++DF + GAD  TFH EA      L+  I+ +G+
Sbjct  65   F-------------DVHLMVSRPADLIEDFVQAGADFLTFHIEAEVHAHRLIHAIRGRGV  111

Query  124  KAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAK----FPH  179
            K   ++ P T V  L E+ P +D+ LVMTV PGF GQ+ +   + KV  L          
Sbjct  112  KVGISLVPSTPVAALSEVLPFVDLVLVMTVNPGFSGQQMIAHCLSKVSALVQMRTERGYS  171

Query  180  LNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
              I VDGG+   T+P+A  AGA+VIV+G++ F+
Sbjct  172  YMISVDGGIDCRTLPQALDAGADVIVSGSAFFS  204


>gi|17380276|sp|Q9CCP9|RPE_MYCLE  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=224

 Score =  162 bits (411),  Expect = 8e-40, Method: Composition-based stats.
 Identities = 92/213 (43%), Positives = 136/213 (63%), Gaps = 19/213 (8%)

Query  4    PIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            P+IAPSILA+DFA L  E    + A ADWLH+DVMDGHFVPN+T+G P+V SL  +   P
Sbjct  3    PLIAPSILAADFARLTDE--AAVVASADWLHVDVMDGHFVPNLTIGLPVVQSLLAASDIP  60

Query  64   GDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGI  123
                          DCH+M++NP++W   +A+ GA   TFH EAT +P+ +   I++ G 
Sbjct  61   -------------MDCHLMIDNPDRWAPPYAEAGAYNVTFHAEATDNPVGVAHDIRTAGA  107

Query  124  KAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP----H  179
            KA   +KPGT ++   ++ PH D  L+M+VEPGFGGQ F+ +++ KV T+R         
Sbjct  108  KAGIGVKPGTPLNPYLDILPHFDTLLIMSVEPGFGGQAFIPEVLSKVRTVRKMVDAGELT  167

Query  180  LNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
            + +++DGG+  +TI +AA+AG +  VAG++V+ 
Sbjct  168  ILVEIDGGINADTIEQAAEAGVDCFVAGSAVYG  200


>gi|7674396|sp|Q9YGA9|TRPA_PYRKO  Tryptophan synthase alpha chain
Length=251

 Score =  162 bits (410),  Expect = 1e-39, Method: Composition-based stats.
 Identities = 42/251 (16%), Positives = 85/251 (33%), Gaps = 24/251 (9%)

Query  3    KPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K  + P + A D            V    A  + + +    F   +  G+ I  S  R++
Sbjct  4    KGSLIPYLTAGDPSVEKTLEFLLAVEEF-AGLIELGI---PFSDPMADGKTIQESHYRAL  59

Query  61   PRPGDASNTEKKPTAF-----FDCHMM-VENP------EKWVDDFAKCGADQFTFHYEAT  108
                   +T +    F         +M   NP      +K++ +    GAD         
Sbjct  60   RNGFKLDDTFRILREFRRHSSTPVILMTYYNPVFRTGVKKFLGEAKASGADGILVVDLPV  119

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDM-  166
                  +   K +G+K      P T  + L E+         ++++    G +  + +  
Sbjct  120  SHAGEFLDAAKEEGLKTVFLAAPNTPDERLREIDKASTGFVYLISLYGTTGARDRLPETA  179

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTS----VFTAADPHDVISF  222
               V   R    +      G   +E + +  KAGA+ +V G++    +  + +P + +  
Sbjct  180  FEFVRRARKICNNKLAVGFGVSRREQVEELLKAGADGVVVGSALIELISRSENPVEELRR  239

Query  223  MKEEVSKELRS  233
               E+S   R+
Sbjct  240  KVAELSGYSRA  250


>gi|28380179|sp|Q8KX32|TRPA_SYNP2  Tryptophan synthase alpha chain
Length=264

 Score =  160 bits (404),  Expect = 6e-39, Method: Composition-based stats.
 Identities = 32/248 (12%), Positives = 72/248 (29%), Gaps = 25/248 (10%)

Query  6    IAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            + P I A D            +  AGAD++ + V    +   +  G  I  +  R++ R 
Sbjct  19   LIPFITAGDPDLETTEQALKILDAAGADFIELGV---PYSDPLADGPTIQAAATRALSRG  75

Query  64   GDASNTEKKPT------AFFDCHMMVENP------EKWVDDFAKCGADQFTFHYEATQDP  111
                                       NP      + ++   A  G           ++ 
Sbjct  76   VTLEQVLAIVQRVHGQLTAPIILFTYYNPIFYRGIDAFMAQVAAAGVKGLVIPDLPLEES  135

Query  112  LHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--FMEDMMPK  169
              ++    S G+     + P +  + +  +A      + +    G  G +      +   
Sbjct  136  QMVLDAATSHGLDLILLVAPTSPTERIEAIAKASQGFIYLVSVTGVTGARTSVASRVGEL  195

Query  170  VETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT---AADPHD---VISFM  223
            +  LR           G        +  + GA+ ++ G++V        P +    +   
Sbjct  196  LPKLRQVTDKPIGVGFGVSDPAQARQLKEWGADGVIVGSAVVKRLATGTPAEGLAAVKEF  255

Query  224  KEEVSKEL  231
             E + + +
Sbjct  256  CESLKEAI  263


>gi|73622026|sp|Q5ZVY3|TRPA_LEGPH  Tryptophan synthase alpha chain
Length=272

 Score =  158 bits (400),  Expect = 1e-38, Method: Composition-based stats.
 Identities = 38/255 (14%), Positives = 85/255 (33%), Gaps = 27/255 (10%)

Query  3    KPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K +++P I A D          H+++ +GAD L + +    F   +  G  I  ++ R++
Sbjct  16   KKMLSPYITAGDPYPELTVSLMHQLVKSGADVLELGI---PFSDPMAEGPVIQRAMERAL  72

Query  61   PRPGDASNTEKKPTAF------FDCHMM-VENPEK------WVDDFAKCGADQFTFHYEA  107
                   +       F          +M   NP +      +     + G D        
Sbjct  73   AHSIHCDDVLNMVRQFRKTDTETPVILMGYLNPIEQYGYDLFAQQAVEAGVDGTILVDLP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMM  167
             ++   + ++ +  G+ +     P TS + +  +  H +  L      G  G   ++   
Sbjct  133  PEEADGVSRVWQKHGLYSIYLCSPTTSAERMNYINQHANGYLYYVSLKGVTGSDALKLPE  192

Query  168  PKVETL-RAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT--------AADPHD  218
             K + L R     L + V  G+    +       A+ ++ G ++            DP  
Sbjct  193  LKAQYLQRKAQSKLPLMVGFGIKTPEMAAQVAEFADGVIVGAALINEIIEAYEAKKDPLQ  252

Query  219  VISFMKEEVSKELRS  233
                +   + + + +
Sbjct  253  ASGALLSSMRQAIDN  267


>gi|2851605|sp|P51013|RPE_RHORU  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (R5P3E)
Length=225

 Score =  158 bits (399),  Expect = 2e-38, Method: Composition-based stats.
 Identities = 79/234 (33%), Positives = 121/234 (51%), Gaps = 17/234 (7%)

Query  1    MVKPI-IAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
            M + I IAPS+L++DFA     C      GAD LH DVMD H+VPN+T+G  +  +LR  
Sbjct  1    MTRAIRIAPSLLSADFAISRPRCPSDGRTGADILHFDVMDNHYVPNLTVGPLVCAALRPH  60

Query  60   VPRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIK  119
               P              D H+M    +  +D FA+ GAD  TFH EA+      V++I+
Sbjct  61   TSLP-------------IDVHLMTRPVDPLIDSFAEAGADMITFHPEASDHVHRSVQMIR  107

Query  120  SKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLR--AKF  177
             +G+KA  A+ P + + +L  +   LD+ L+M+V PGFGGQ F+   +PK+  L    + 
Sbjct  108  KRGLKAGVALNPASPLSLLDHILEDLDLVLIMSVNPGFGGQSFIPSALPKIAALANGRRR  167

Query  178  PHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKEL  231
                 +VDGG+        A+ GA+ I+   ++F A+D    I+ ++      L
Sbjct  168  ACRGDRVDGGVNPADARALARPGAD-ILVRLAIFGASDRAKAIASIRGAAESGL  220


>gi|73622025|sp|Q5X5Q1|TRPA_LEGPA  Tryptophan synthase alpha chain
Length=272

 Score =  157 bits (398),  Expect = 3e-38, Method: Composition-based stats.
 Identities = 39/255 (15%), Positives = 86/255 (33%), Gaps = 27/255 (10%)

Query  3    KPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K +++P I A D          H+++ +GAD L + +    F   +  G  I  ++ R++
Sbjct  16   KKMLSPYITAGDPYPELTVSLMHQLVKSGADVLELGI---PFSDPMAEGPVIQRAMERAL  72

Query  61   PRPGDASNTEKKPTAF------FDCHMM-VENPEK------WVDDFAKCGADQFTFHYEA  107
                   +       F          +M   NP +      +     + GAD        
Sbjct  73   AHSIHCDDVLNMVRQFRKTDTETPVILMGYLNPIEQYGYDLFAQQAVEAGADGTILVDLP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMM  167
             ++   + ++ +  G+ +     P TS + +  +  H +  L      G  G   ++   
Sbjct  133  PEEADGVSRVWQKHGLYSIYLCSPTTSAERMNFINQHANGYLYYVSLKGVTGSDALKLPE  192

Query  168  PKVETL-RAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT--------AADPHD  218
             K + L R     L + V  G+    +       A+ ++ G ++            DP  
Sbjct  193  LKAQYLQRKAQSKLPLMVGFGIKTPEMAAQVAEFADGVIVGAALINEIIEAYEAKKDPLQ  252

Query  219  VISFMKEEVSKELRS  233
                +   + + + +
Sbjct  253  ASGALLSSMRQAIDN  267


>gi|73622027|sp|Q5WX31|TRPA_LEGPL  Tryptophan synthase alpha chain
Length=272

 Score =  157 bits (397),  Expect = 3e-38, Method: Composition-based stats.
 Identities = 38/255 (14%), Positives = 85/255 (33%), Gaps = 27/255 (10%)

Query  3    KPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K +++P I A D          H+++ +GAD L + +    F   +  G  I  ++ R++
Sbjct  16   KKMLSPYITAGDPYPELTVSLMHQLVKSGADVLELGI---PFSDPMAEGPVIQRAMERAL  72

Query  61   PRPGDASNTEKKPTAF------FDCHMM-VENPEK------WVDDFAKCGADQFTFHYEA  107
                   +       F          +M   NP +      +     + G D        
Sbjct  73   AHSIHCDDVLNMVRQFRKTDTETPVILMGYLNPIEQYGYDLFAQQAVEAGVDGTILVDLP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMM  167
             ++   + ++ +  G+ +     P TS + +  +  H +  L      G  G   ++   
Sbjct  133  PEEADGVSRVWQKHGLYSIYLCSPTTSAERMNFINQHANGYLYYVSLKGVTGSDALKLPE  192

Query  168  PKVETL-RAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT--------AADPHD  218
             K + L R     L + V  G+    +       A+ ++ G ++            DP  
Sbjct  193  LKAQYLQRKAQSKLPLMVGFGIKTPEMAAQVAEFADGVIVGAALINEIIEAYEAKKDPLQ  252

Query  219  VISFMKEEVSKELRS  233
                +   + + + +
Sbjct  253  ASGALLSSMRQAIDN  267


>gi|28380191|sp|Q8TLP4|TRPA_METAC  Tryptophan synthase alpha chain
Length=272

 Score =  156 bits (394),  Expect = 9e-38, Method: Composition-based stats.
 Identities = 38/245 (15%), Positives = 84/245 (34%), Gaps = 17/245 (6%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +  +   ++A D            ++N GAD + +      F   +  G  I  + +R+
Sbjct  26   KEGALIGYVMAGDPSAEATFGIVKALVNGGADIIELGF---PFSDPVADGPTIQAAGQRA  82

Query  60   VPRPGDASNTEKKPT----AFFDCHMMVENP------EKWVDDFAKCGADQFTFHYEATQ  109
            +    D  +  +             M   NP      +K+V+  A  G           +
Sbjct  83   LAAGMDIEHYFELVRGLGVEVPLVCMTYYNPVFRYGVDKFVEHAADAGISGLIIPDIPVE  142

Query  110  DPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPK  169
            +   L    +  G+     + P T+   + ++       + +    G  G +       K
Sbjct  143  EAADLKSSCEKYGLDLIFLVAPTTTDARIRKILERGSGFIYLVSRLGVTGARADVSGSTK  202

Query  170  VETLRAKFPHLNIQVDGGLGK-ETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVS  228
             E L      +   V  G+   +   +  KAGA+ ++ G+      +  + ++   E ++
Sbjct  203  -ELLSRVKTDIPKAVGFGISTGKQAAEVRKAGADAVIVGSVFVRIIEEGNGVNEKLEALA  261

Query  229  KELRS  233
            +EL+S
Sbjct  262  RELKS  266


>gi|28380182|sp|Q8PT96|TRPA_METMA  Tryptophan synthase alpha chain
Length=271

 Score =  155 bits (393),  Expect = 1e-37, Method: Composition-based stats.
 Identities = 41/245 (16%), Positives = 84/245 (34%), Gaps = 17/245 (6%)

Query  2    VKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +  +   ++A D  F         +   GAD + +      F   +  G  I  + +R+
Sbjct  25   KEGALIGYVMAGDPTFEASSEVVKALAKGGADIIELGF---PFSDPVADGPTIQVAGQRA  81

Query  60   VPRPGDASNTEKKPTA----FFDCHMMVENP------EKWVDDFAKCGADQFTFHYEATQ  109
            +    D         A         M   NP      EK+V++ A+ G           +
Sbjct  82   LAEGMDIERYFAFARALEVDVPLVCMTYYNPVFRYGVEKFVENAAEAGISGLIIPDIPVE  141

Query  110  DPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPK  169
            +   L     + G+     + P T+   + ++       + +    G  G +       K
Sbjct  142  EAADLKTGCDAHGLDLIFLVAPTTTEARIRKILQRGSGFIYLVSRLGVTGARDDVAGSTK  201

Query  170  VETLRAKFPHLNIQVDGGLGK-ETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVS  228
             E L      +   V  G+   E   +  KAGA+ ++ G++     +    ++   E ++
Sbjct  202  -ELLSRVNTDIPKAVGFGISTGEQAAEVRKAGADGVIVGSAFVRIIEEGTDVNERLETLA  260

Query  229  KELRS  233
            +EL+S
Sbjct  261  RELKS  265


>gi|28380194|sp|Q8TYA2|TRPA_METKA  Tryptophan synthase alpha chain
Length=275

 Score =  155 bits (393),  Expect = 1e-37, Method: Composition-based stats.
 Identities = 35/231 (15%), Positives = 79/231 (34%), Gaps = 17/231 (7%)

Query  15   FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSL---RRSVPRPGDASNTEK  71
                      + + G D L + V    F   I  G  I  ++    R+   P D     +
Sbjct  32   LEETVSLARALRDGGVDILELGV---PFSEPIADGPTIQKAVDEALRAGTTPWDCLEVAE  88

Query  72   KPTAFFDCHM-MVEN------PEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIK  124
            + + F    +    N       E+++   A+ G           ++   +  + +   I 
Sbjct  89   EVSEFVPVVLLCYYNTLHANGFERYLSAAAEAGVSGIIVADMPVEESDEVHSVARDLEID  148

Query  125  AACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--EDMMPKVETLRAKFPHLNI  182
                + P T+ + L ++       + +    G  G +    ED +  V  +R     + +
Sbjct  149  VIYLVAPSTTDERLKKIGERASGFVYVISRYGVTGARRDLSEDTLELVRWVRDHV-DVPV  207

Query  183  QVDGGLGKE-TIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELR  232
             V  G+ +   + +   AGA+  + G++        + I+  +E V +  +
Sbjct  208  AVGFGISERWHVEEVIAAGADGAIVGSAFIKEIHRSEDIAEAEERVRELAK  258


>gi|1717756|sp|P51382|TRPA_PORPU  Tryptophan synthase alpha chain
Length=273

 Score =  154 bits (390),  Expect = 2e-37, Method: Composition-based stats.
 Identities = 32/243 (13%), Positives = 81/243 (33%), Gaps = 22/243 (9%)

Query  2    VKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +  + P I A D    +       +   GAD + + +    +   +  G  I  +  R+
Sbjct  23   KQCALIPFITAGDPDLVSTSKALKILDQHGADIIELGL---PYSDPLADGPIIQAASSRA  79

Query  60   VPRPGDASNTEKKPT------AFFDCHMMVENP------EKWVDDFAKCGADQFTFHYEA  107
            + +  + +N                      NP        ++   ++ G          
Sbjct  80   LKQSINLNNILDMVNITSSNIVAPIVLFTYYNPVLNLGINNFISAISRAGIKGLLIPDLP  139

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK-FMEDM  166
             ++  +++ + K   I+    + P +S++ + ++       + +    G  GQK  +   
Sbjct  140  IEESDYIISVCKLFNIELIFLLSPTSSIERINKIVEQAPGCIYLVSTTGVTGQKPELTGK  199

Query  167  MPKVET-LRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT---AADPHDVISF  222
            + ++   ++       I   G    E I +      N IV G++      +  P + +  
Sbjct  200  LKRLTETIKKMTQKPIILGFGISTAEQIKEIKGWNINGIVIGSAFVKRLSSDFPEEGLRK  259

Query  223  MKE  225
            +K+
Sbjct  260  IKD  262


>gi|73621995|sp|Q65I36|TRPA_BACLD  Tryptophan synthase alpha chain
Length=267

 Score =  153 bits (387),  Expect = 5e-37, Method: Composition-based stats.
 Identities = 36/253 (14%), Positives = 82/253 (32%), Gaps = 34/253 (13%)

Query  4    PIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVP  61
             +  P I A D            +  AGA  L + V    +   +  G  I  + +R++ 
Sbjct  11   KLFVPFITAGDPLPEISIELAKSLQEAGASALELGV---PYSDPLADGPVIQRASKRALD  67

Query  62   R------PGDASNTEKKPTAFFDCHM-MVENP------EKWVDDFAKCGADQFTFHYEAT  108
                           KK        +    NP      + +     +   D         
Sbjct  68   NDMNIVKAIRLGGEMKKNGVHIPIILFTYYNPVLQLDTDHFFALLRQNQLDGLLVPDLPF  127

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--FMEDM  166
            ++ ++L +  K  GI     + P TS   + ++    +  +      G  G +  F + +
Sbjct  128  EESVYLQQQCKKHGITYISLVAP-TSESRIQKITQQAEGFVYCVSSLGVTGVRNEFEDSV  186

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
               + +++     + + V  G+      +     A+ +V G+++         I  +K+E
Sbjct  187  SSFIRSVKGM-SSVPVAVGFGISSSKQVEMMNELADGVVVGSALVRK------IEELKDE  239

Query  227  V------SKELRS  233
            +       + L++
Sbjct  240  LVAPETREQALKA  252


>gi|73622038|sp|Q7VD15|TRPA_PROMA  Tryptophan synthase alpha chain
Length=267

 Score =  152 bits (385),  Expect = 1e-36, Method: Composition-based stats.
 Identities = 32/237 (13%), Positives = 79/237 (33%), Gaps = 19/237 (8%)

Query  6    IAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            + P I+A D            +   GAD + + +    +   +  G  I  +  R++   
Sbjct  21   LMPFIMAGDPDVNTSAEILIMLEKKGADIIELGI---PYSDPLADGPIIQKAASRALNSG  77

Query  64   GDASNTEKKPTA------FFDCHMMVENP------EKWVDDFAKCGADQFTFHYEATQDP  111
                +  +  +                NP      E++  D +K GA          ++ 
Sbjct  78   TSPKSVLEMLSTLKTKLSVPIILFTYSNPLLNYGMEEFCIDASKAGAAGLVVPDLPLEET  137

Query  112  LHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK-FMEDMMPKV  170
              L  +  SK +     + P T  + + +++   +    +    G  G++  +E+ +  +
Sbjct  138  EKLSSIALSKNLDLVLLVAPTTPKERMRKISQRSNGFTYLVSVTGVTGERSALENRVQLL  197

Query  171  ETLRAKFPHLNIQVDGGLG-KETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
                  F    + V  G+   + + +  + GA+  + G+++             +E 
Sbjct  198  INELRGFSSTPVAVGFGISDTKHVIQVKRWGADGAIIGSALVKRISNATTGQEAEEA  254


>gi|73621996|sp|Q5WGS0|TRPA_BACSK  Tryptophan synthase alpha chain
Length=269

 Score =  152 bits (384),  Expect = 1e-36, Method: Composition-based stats.
 Identities = 34/259 (13%), Positives = 77/259 (29%), Gaps = 33/259 (12%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
               +  P I A D            +  +GAD L + +    +   +  G  I  + +R+
Sbjct  11   KGNLFIPFITAGDPVREATIALALSLQRSGADVLELGI---PYSDPLADGPVIQNASKRA  67

Query  60   VPRPGDASNTEKKPTA------FFDC-HMMVENP------EKWVDDFAKCGADQFTFHYE  106
            +      +                        NP      E++ +     G D       
Sbjct  68   LAGGMTLAKAMALVPEMRKEGLTIPVIVFTYANPLLQFGFERFCETACDYGIDGLLVPDL  127

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF--ME  164
              ++   L    + +G+     + P TS   +  +A      L      G  G +     
Sbjct  128  PFEESETLANECEKQGLALISLVAP-TSQQRIKAIASRAQGFLYCVSSLGVTGARKTLHP  186

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF-----------TA  213
             +   ++ ++   P   +   G    E + +     A+ +V G+++             A
Sbjct  187  QVEAFLKLVKEASPVPFVVGFGISSYEQVEE-MGRHADGVVIGSAIVEQIGLRCEALKQA  245

Query  214  ADPHDVISFMKEEVSKELR  232
                + +  +++ V+  L 
Sbjct  246  ESRDEAVKEIEQYVNSLLH  264


>gi|73622020|sp|Q7NHC5|TRPA_GLOVI  Tryptophan synthase alpha chain
Length=276

 Score =  152 bits (384),  Expect = 1e-36, Method: Composition-based stats.
 Identities = 37/247 (14%), Positives = 72/247 (29%), Gaps = 22/247 (8%)

Query  6    IAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
              P I A D            +   GAD L + +    +   +  G  I  +  R++ R 
Sbjct  25   FIPFITAGDPDLETTAEALLTLDRNGADLLELGL---PYSDPLADGPTIQAAATRALARG  81

Query  64   GDASNTEKKPTAFFD------CHMMVEN------PEKWVDDFAKCGADQFTFHYEATQDP  111
                                       N       E +V+  A  GA          ++ 
Sbjct  82   TTPGAVLDLVARLTPELRAPLIVFTYFNLILAVGIEAFVERLAASGASGLLVPDLPVEEG  141

Query  112  LHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--FMEDMMPK  169
              L      +G+     + P +  + L  +A      + +    G  G +      +   
Sbjct  142  DALQTAANVQGLDVIWLVAPTSPPERLRRIAERTTGFVYLVSTTGVTGARTQVASSVRTS  201

Query  170  VETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT---AADPHDVISFMKEE  226
            +  LRA          G    E   + A  GA+ ++ G++       A P + +  + E 
Sbjct  202  LAQLRALTTRPVAVGFGISTPEQAHEVASLGADGVIVGSACVQLLATAAPEERLGQLAEF  261

Query  227  VSKELRS  233
              +  ++
Sbjct  262  CRQLKKA  268


>gi|418563|sp|P32719|ALSE_ECOLI  D-allulose-6-phosphate 3-epimerase
Length=231

 Score =  151 bits (383),  Expect = 2e-36, Method: Composition-based stats.
 Identities = 71/232 (30%), Positives = 109/232 (46%), Gaps = 21/232 (9%)

Query  6    IAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGD  65
            I+PS++  D      +  + I++ AD+ HID+MDGHFVPN+TL                 
Sbjct  3    ISPSLMCMDLLKFKEQI-EFIDSHADYFHIDIMDGHFVPNLTLSP-------------FF  48

Query  66   ASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQ-DPLHLVKLIKSKGIK  124
             S  +K  T   DCH+MV  P+ ++   A+ GAD  T H E        L+  I+   +K
Sbjct  49   VSQVKKLATKPLDCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEIRRHDMK  108

Query  125  AACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAK----FPHL  180
                + P T V+ +       D   VMTV+PGF GQ F+ +M+ K+  L+A         
Sbjct  109  VGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKLAELKAWREREGLEY  168

Query  181  NIQVDGGLGKETIPKAAKAGANVIVAG-TSVFT-AADPHDVISFMKEEVSKE  230
             I+VDG   + T  K   AGA+V + G + +F  A +  +    M  ++   
Sbjct  169  EIEVDGSCNQATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQILAA  220


>gi|20140838|sp|Q9KCA9|TRPA_BACHD  Tryptophan synthase alpha chain
Length=265

 Score =  151 bits (383),  Expect = 2e-36, Method: Composition-based stats.
 Identities = 30/227 (13%), Positives = 68/227 (29%), Gaps = 20/227 (8%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             K +  P I A D            +  AGAD L + +    +   +  G  I  + +R+
Sbjct  11   KKNLFIPFITAGDPNPEVTIELALTLEEAGADILELGI---PYSDPLADGPVIQAASKRA  67

Query  60   VPRPGDASNTEKKPT-------AFFDCHMMVENP------EKWVDDFAKCGADQFTFHYE  106
            +                               NP      E++V   A    D       
Sbjct  68   LKHEMTLEKALSLVPKMRAQGLTIPVIVFTYVNPLLQYGEEQFVKRAADYQVDGILVPDM  127

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK-FMED  165
              ++   L    +   +     + P ++   + ++A      +      G  G +  ++ 
Sbjct  128  PFEEGEVLQAACQEHNLSLISLVAPTSN-KRIEKIAARAQGFVYCVSSLGVTGLRDELDP  186

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
             + +          + + V  G+ +    +A    A+ +V G+++  
Sbjct  187  RVHEFLQTVKTHASVPVVVGFGISRREQVEALAENADGVVVGSAIVK  233


>gi|2501410|sp|P77960|TRPA_SYNY3  Tryptophan synthase alpha chain
Length=264

 Score =  151 bits (383),  Expect = 2e-36, Method: Composition-based stats.
 Identities = 31/223 (13%), Positives = 72/223 (32%), Gaps = 19/223 (8%)

Query  6    IAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            + P + A D   A        +  AGAD + + V    +   +  G  I  +  R++ + 
Sbjct  19   LIPFLTAGDPDLATTAEALRILDRAGADLIELGV---PYSDPLADGPVIQAAATRALQKG  75

Query  64   GDASNTEKKPTAF------FDCHMMVENP------EKWVDDFAKCGADQFTFHYEATQDP  111
                +                      NP      E ++D     G           ++ 
Sbjct  76   VKLDDVLAIVREVHQDIAAPIILFTYYNPIFYQGVEVFLDKIKAAGVKGLVVPDLPLEES  135

Query  112  LHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDMMPKV  170
              L++    +G++    + P +S +    +A        +++V    G +  +   +  +
Sbjct  136  DRLLEATAERGLELILLVAPTSSPERQTAIAKKSQGFVYLVSVTGVTGVRTEVGSRVEAL  195

Query  171  ETLRAKFPHLNIQVDGGLG-KETIPKAAKAGANVIVAGTSVFT  212
                 +     I V  G+   E   +    GA+ ++ G+++  
Sbjct  196  LAGMRQVTDKPIGVGFGISQPEQAEQVKAWGADAVIVGSAMVK  238


>gi|73622035|sp|Q8ESU5|TRPA_OCEIH  Tryptophan synthase alpha chain
Length=262

 Score =  151 bits (383),  Expect = 2e-36, Method: Composition-based stats.
 Identities = 36/227 (15%), Positives = 74/227 (32%), Gaps = 20/227 (8%)

Query  2    VKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             KPI  P I+A D    NL      +  AGA  + + +    F   +  G  I  + +R+
Sbjct  17   KKPIFVPYIMAGDGGIDNLNKRIQFLEEAGASAVELGI---PFSDPVADGPVIQDAGQRA  73

Query  60   VPRPGDASNTEKKPTA-----FFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEA  107
            +       +  +   +          +M           E++  D ++ G D        
Sbjct  74   LANKTTIGSVLEALESEKSQRNIPVVLMTYINPVWKYGFEQFARDCSQAGVDGIIIPDIP  133

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--ED  165
             ++   +   +    I         ++ D L  +A   +  L      G  G++     D
Sbjct  134  MEEEDDVASSLTQHDIAFIRLAAMTSTEDRLERIAKRSEGFLYAVSVTGTTGERAQHEND  193

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
                +E L+    H+ +    G+      +   A  + +V G+ +  
Sbjct  194  AFHFLEKLKQ-ISHVPVLAGFGISTAERARELSAACDGVVVGSKIVQ  239


>gi|73622019|sp|Q74AI3|TRPA_GEOSL  Tryptophan synthase alpha chain
Length=264

 Score =  151 bits (382),  Expect = 2e-36, Method: Composition-based stats.
 Identities = 35/253 (13%), Positives = 75/253 (29%), Gaps = 26/253 (10%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  +   I A D   A        +  +GAD + + V    F   +  G  I  S  R++
Sbjct  16   RKALVTFITAGDPDLAATEALIPLLAESGADIVELGV---PFSDPMADGPTIQLSSERAL  72

Query  61   PRPGDASNTEKKPTA-----FFDCHMM-VENP------EKWVDDFAKCGADQFTFHYEAT  108
                                     +M   NP      E++  D +  G D         
Sbjct  73   AAGTTLPKILDMVRRVRTRCQVPIVLMGYYNPILIHGLERFAADASAAGVDGVLLVDLPP  132

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--EDM  166
            ++           G+     + P +    + ++A      +      G  G +      +
Sbjct  133  EEAAEFKACADRHGLDVIFLLTPTSDEGRIRKVARQARGFVYYVSVTGVTGARSGVEASV  192

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT------AADPHDVI  220
               V  +R     + + V  G+          A A+ +V G+++        AA+    +
Sbjct  193  SSNVAAIREAI-TVPVVVGFGISTPDQAAQVAASADGVVVGSAIVKLFERFTAAELGREV  251

Query  221  SFMKEEVSKELRS  233
            +     + + + +
Sbjct  252  ATFVSALREAIGN  264


>gi|136261|sp|P26920|TRPA_METTM  Tryptophan synthase alpha chain
Length=265

 Score =  151 bits (382),  Expect = 2e-36, Method: Composition-based stats.
 Identities = 36/245 (14%), Positives = 78/245 (31%), Gaps = 24/245 (9%)

Query  6    IAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
              P ++A D            +++AGAD L I      F   I  G  +  +  R++   
Sbjct  15   FVPFVVAGDPDMETSVEIIRTLVDAGADALEIGF---PFSDPIADGTSVQEADLRALNSG  71

Query  64   GDASNTEKKPT-----AFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEATQDP  111
                +  +              ++V          +++    A+ G           ++ 
Sbjct  72   MTTDDCFRLIERIREFTSVPVGLLVYYNLIYRMGADEFYRRAAEAGVTGILAADLPPEEA  131

Query  112  LHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF--MEDMMPK  169
               ++  +  GI     + P T    L  ++        +    G  G +    E  +  
Sbjct  132  GDALRAAERYGIDQIFIVAPTTDNQRLKMISEVSSGFHYLVSVMGVTGARSRVEESTLEL  191

Query  170  VETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF-----TAADPHDVISFMK  224
            +E ++       +   G    E +   A AGA+ ++ G+++         D   ++  + 
Sbjct  192  IERVKGAGSLPVMVGFGVSQPEHVRMLADAGADGVIVGSAIIDLISKNLDDRERMLQEIY  251

Query  225  EEVSK  229
            E V K
Sbjct  252  EMVRK  256


>gi|38258736|sp|Q88B60|TRPA_PSESM  Tryptophan synthase alpha chain
Length=270

 Score =  151 bits (382),  Expect = 2e-36, Method: Composition-based stats.
 Identities = 44/255 (17%), Positives = 79/255 (30%), Gaps = 28/255 (10%)

Query  3    KPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            + ++   I A D            +  AGAD + + +    F   +  G  I  +  R++
Sbjct  16   RAVLVTFITAGDPGYDTSLKVLKGLPAAGADVIELGM---PFTDPMADGVAIQLATLRAL  72

Query  61   PRPGDASNTEKKPTAF------FDCHMM-VENP------EKWVDDFAKCGADQFTFHYEA  107
                    T +  + F          +M   NP      E +V    + G D        
Sbjct  73   DAGQTLLKTLQMVSEFRVDDQTTPIVLMGYYNPIHRFGVEAFVAQAKEAGVDGLIIVDLP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFMED  165
             +    L    ++ GI       P T    L  +       +      G  G      E 
Sbjct  133  PEHDAELATPAQASGIDFIRLTTPTTDDARLPRVLERSSGFVYYVSVAGVTGAGSATTEH  192

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTS----VFTAADPHDVIS  221
            +   +  LR     L I V  G+       A    A+ +V G++    + TA  P   I 
Sbjct  193  VTEAIARLRRHT-SLPISVGFGIRTPEQAAAIARLADGVVVGSAFVDKIATAESPEQAID  251

Query  222  F---MKEEVSKELRS  233
                +   +++ +R+
Sbjct  252  GVLTLCAALAEGVRN  266


>gi|11135218|sp|P57365|TRPA_BUCAI  Tryptophan synthase alpha chain
Length=269

 Score =  151 bits (381),  Expect = 2e-36, Method: Composition-based stats.
 Identities = 29/232 (12%), Positives = 72/232 (31%), Gaps = 20/232 (8%)

Query  1    MVKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRR  58
            + +    P ++  D            +I +GAD L I +    F   +  G  +  S  R
Sbjct  14   LKEGCFIPFVVLGDPSLETSIKIIETLIKSGADALEIGI---PFSDPLADGPTVQKSNLR  70

Query  59   SVPRP------GDASNTEKKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHY  105
            ++ +              +K        +++          + +       G D      
Sbjct  71   ALSKNNTFFEYFKILKQLRKKNKKLPIGILIYANLVYNQGIDNFYFQCFNSGLDSVLIAD  130

Query  106  EATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--FM  163
               ++      +     I       P    D L++++ +    + +   PG  G K   +
Sbjct  131  VPIEESKIFYNIANKYKINPIFICPPDADADFLYKISLYAQGFIYVLSRPGVTGIKNNTI  190

Query  164  EDMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAAD  215
                  +  ++       +Q  G    + I +A  +G + ++ G+++    +
Sbjct  191  ALPRDFINKIKKYNSVPLLQGFGISNPKQIKEAISSGLSGVICGSAIINIIE  242


>gi|34222869|sp|Q8DLN9|TRPA_SYNEL  Tryptophan synthase alpha chain
Length=266

 Score =  150 bits (380),  Expect = 3e-36, Method: Composition-based stats.
 Identities = 35/248 (14%), Positives = 76/248 (30%), Gaps = 25/248 (10%)

Query  6    IAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            + P + A D            + + GAD + + +    +   +  G  I  +  R++ R 
Sbjct  21   LIPFLTAGDPDLETTVAALKILDDHGADLIELGM---PYSDPLADGPVIQAAATRALQRG  77

Query  64   GDASNTEKKPT------AFFDCHMMVENPEK------WVDDFAKCGADQFTFHYEATQDP  111
                   +  T                NP        ++   A+ G           ++ 
Sbjct  78   TRLEAVLEMTTDLHQQLTAPLILFSYYNPIYHRGVSSFLKAVAQAGIKGLVIPDLPLEEA  137

Query  112  LHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG--GQKFMEDMMPK  169
              ++    + G++    I P TS + +  +A      + +    G     Q+    +   
Sbjct  138  EPVLAETANLGLELTLLIAPTTSPERMRAIATASQGFIYLVSTTGVTGMRQEMASRVQEL  197

Query  170  VETLRAKFPHLNIQVDGGL-GKETIPKAAKAGANVIVAGTSVFT----AADPHDVISFMK  224
            + TLR   P   I V  G+   E   +    GA+  + G++              ++   
Sbjct  198  LHTLRQITPK-PIGVGFGIASPEHARQVRDWGADAAIVGSAFVKRLAEPDQGLAAVAEFC  256

Query  225  EEVSKELR  232
            + +   L 
Sbjct  257  QSLRTALD  264


>gi|12230945|sp|P07344|TRPA_PSEAE  Tryptophan synthase alpha chain
Length=268

 Score =  150 bits (380),  Expect = 4e-36, Method: Composition-based stats.
 Identities = 39/256 (15%), Positives = 81/256 (31%), Gaps = 28/256 (10%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +  +   + A D   A+       +  AGAD + + +    F   +  G  I  +  R+
Sbjct  15   NRAALVTFVTAGDPDYASSLEILKGLPAAGADVIELGM---PFTDPMADGPAIQLANIRA  71

Query  60   VPRPGDASNTEKKPTAF------FDCHMM-------VENPEKWVDDFAKCGADQFTFHYE  106
            +      + T +    F          +M           E+++ +  + G D       
Sbjct  72   LDGGQTLARTLQMVREFRSGDSETPLVLMGYFNPIHHYGVERFIAEAKEVGVDGLIVVDL  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPH-LDMALVMTVEP-GFGGQKFME  164
              +    L    ++ GI       P T    L  +          ++V          +E
Sbjct  132  PPEHNEDLCHPAQAAGIDFIRLTTPTTGDQRLPTVLEGSSGFVYYVSVAGVTGANAATLE  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTS----VFTAADPHDVI  220
             +   V  LR     L I +  G+       A    A+ +V G++    +  A D    +
Sbjct  192  HVEEAVARLRRHT-DLPIGIGFGIRSAEHAAAVARLADGVVVGSALIDRIAKARDNAQAV  250

Query  221  S---FMKEEVSKELRS  233
                 +  E+++ +R+
Sbjct  251  KDVLALCGELAEGVRN  266


>gi|136373|sp|P00931|TRP_YEAST  Tryptophan synthase
Length=707

 Score =  150 bits (380),  Expect = 4e-36, Method: Composition-based stats.
 Identities = 35/210 (16%), Positives = 72/210 (34%), Gaps = 18/210 (8%)

Query  17   NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKPT--  74
            +         + G D + + +    F   I  G  I  S   ++        T +  +  
Sbjct  33   DTVPILKGFQDGGVDIIELGM---PFSDPIADGPTIQLSNTVALQNGVTLPQTLEMVSQA  89

Query  75   ----AFFDCHMM-VENP------EKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGI  123
                      +M   NP      E+++ D AK GA+ F       ++ L +   I   G+
Sbjct  90   RNEGVTVPIILMGYYNPILNYGEERFIQDAAKAGANGFIIVDLPPEEALKVRNYINDNGL  149

Query  124  KAACAIKPGTSVDVLFELAPHLD-MALVMTVEPGFGGQKFMEDMM-PKVETLRAKFPHLN  181
                 + P T+ + L  L+   D    V++     G Q  +   +   +  +R       
Sbjct  150  SLIPLVAPSTTDERLELLSHIADSFVYVVSRMGTTGVQSSVASDLDELISRVRKYTKDTP  209

Query  182  IQVDGGLGKETIPKAAKAGANVIVAGTSVF  211
            + V  G+      ++  + A+ +V G+ + 
Sbjct  210  LAVGFGVSTREHFQSVGSVADGVVIGSKIV  239


>gi|73621990|sp|Q81GG4|TRPA_BACCR  Tryptophan synthase alpha chain
Length=258

 Score =  149 bits (377),  Expect = 7e-36, Method: Composition-based stats.
 Identities = 34/245 (13%), Positives = 85/245 (34%), Gaps = 29/245 (11%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K    P ++  D     L      +  AGA  + I +    F   +  G  I  + +R++
Sbjct  14   KKAFIPYVMGGDGGLEKLKERIRFLDEAGASIVEIGI---PFSDPVADGPTIQRAGKRAL  70

Query  61   PRPGDA-----SNTEKKPTAFFDCHMMVE-NP------EKWVDDFAKCGADQFTFHYEAT  108
                       +  E +        +M   NP      E+++++  + G D         
Sbjct  71   DSGVTLKGIFQALAEVRKEVQMPFVLMTYLNPVLAFGKERFIENCIEAGVDGIIVPDLPY  130

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG--GQKFMEDM  166
            ++   +  L++   I     +   + ++ + ++    +  +      G     Q F E++
Sbjct  131  EEQNIIAPLLREVNIALIPLVTVTSPIERIEKITSESEGFVYAVTVAGVTGVRQNFKEEI  190

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
               +E +++   +L +    G+  +   +      + +V G+          VI  ++ E
Sbjct  191  HSYLEKVKSHV-NLPVVAGFGISTKEHVEEMVTICDGVVVGS---------KVIELLENE  240

Query  227  VSKEL  231
              +E+
Sbjct  241  KREEI  245


>gi|73621991|sp|Q63EC6|TRPA_BACCZ  Tryptophan synthase alpha chain
Length=258

 Score =  149 bits (377),  Expect = 8e-36, Method: Composition-based stats.
 Identities = 34/245 (13%), Positives = 85/245 (34%), Gaps = 29/245 (11%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K    P ++  D     L      +  AGA  + I +    F   +  G  I  + +R++
Sbjct  14   KKAFIPYVMGGDGGLEILKERIRFLDEAGASIVEIGI---PFSDPVADGPTIQRAGKRAL  70

Query  61   PRPGDA-----SNTEKKPTAFFDCHMMVE-NP------EKWVDDFAKCGADQFTFHYEAT  108
                       +  E +        +M   NP      E+++++  + G D         
Sbjct  71   DSGVTVKGIFQALIEARKEVQIPFVLMTYLNPVLAFGKERFIENCMEAGVDGIIVPDLPY  130

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG--GQKFMEDM  166
            ++   +  L++   I     +   + ++ + ++    +  +      G     Q F +++
Sbjct  131  EEQDIIAPLLREANIALIPLVTVTSPIERIKKITSESEGFVYAVTVAGVTGVRQNFKDEI  190

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
               +E +++   HL +    G+  +   +      + +V G+          VI  ++ E
Sbjct  191  HSYLEKVKSHT-HLPVVAGFGISTKEHVEEMVTICDGVVVGS---------KVIELLENE  240

Query  227  VSKEL  231
              +E+
Sbjct  241  KREEI  245


>gi|38258595|sp|Q8FXY6|TRPA_BRUSU  Tryptophan synthase alpha chain
Length=279

 Score =  149 bits (377),  Expect = 8e-36, Method: Composition-based stats.
 Identities = 41/260 (15%), Positives = 78/260 (30%), Gaps = 33/260 (12%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +P +    +  D            +  AGAD + + +    F   +  G  I  +  R++
Sbjct  17   RPALVTYFMGGDPDLETALKVMKALPKAGADVIELGM---PFSDPMADGPAIQAAGLRAL  73

Query  61   PRPGDASNTEKKPTAF------FDCHMM-------VENPEKWVDDFAKCGADQFTFHYEA  107
                  + T      F          MM       V   E+++ D    G D        
Sbjct  74   NAGQTLAKTLYMAAEFRKEDDTTPIVMMGYYNPIYVYGVERFLTDAKASGVDGLIVVDLP  133

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMED--  165
            ++    L       GI       P T    L ++  +    +      G  G    +   
Sbjct  134  SEMDAELCIPAMKAGINFIRLTTPTTDDKRLPKVLHNSSGFVYYVSMNGITGAAIADTAK  193

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAA-----------  214
            +   V  ++     L I V  G+       A    A+ +V GT++  A            
Sbjct  194  VGEAVRHIKKST-DLPICVGFGVKTPEQAAAIATHADGVVVGTAIVNAIAGELDEKGKVK  252

Query  215  -DPHDVISFMKEEVSKELRS  233
             DP    + +   +++ +R+
Sbjct  253  GDPVAAATRLVHALAESVRA  272


>gi|73621988|sp|Q81TL7|TRPA_BACAN  Tryptophan synthase alpha chain
Length=258

 Score =  149 bits (376),  Expect = 9e-36, Method: Composition-based stats.
 Identities = 34/245 (13%), Positives = 85/245 (34%), Gaps = 29/245 (11%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K    P ++  D     L      +  AGA  + I +    F   +  G  I  + +R++
Sbjct  14   KKAFIPYVMGGDGGLEILKERIRFLDEAGASIVEIGI---PFSDPVADGPTIQRAGKRAL  70

Query  61   PRPGDA-----SNTEKKPTAFFDCHMMVE-NP------EKWVDDFAKCGADQFTFHYEAT  108
                       +  E +        +M   NP      E+++++  + G D         
Sbjct  71   DSGVTVKGIFQALIEVRKEVQIPFVLMTYLNPVLAFGKERFIENCMEAGVDGIIVPDLPY  130

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG--GQKFMEDM  166
            ++   +  L++   I     +   + ++ + ++    +  +      G     Q F +++
Sbjct  131  EEQDIIAPLLREANIALIPLVTVTSPIERIKKITSESEGFVYAVTVAGVTGVRQNFKDEI  190

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
               +E +++   HL +    G+  +   +      + +V G+          VI  ++ E
Sbjct  191  HSYLEKVKSHT-HLPVVAGFGISTKEHVEEMVTICDGVVVGS---------KVIELLENE  240

Query  227  VSKEL  231
              +E+
Sbjct  241  KREEI  245


>gi|73621994|sp|Q6HLU3|TRPA_BACHK  Tryptophan synthase alpha chain
Length=258

 Score =  148 bits (375),  Expect = 1e-35, Method: Composition-based stats.
 Identities = 34/245 (13%), Positives = 85/245 (34%), Gaps = 29/245 (11%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K    P ++  D     L      +  AGA  + I +    F   +  G  I  + +R++
Sbjct  14   KKAFIPYVMGGDGGLEILKERIRFLDEAGASIVEIGI---PFSDPVADGPTIQRAGKRAL  70

Query  61   PRPGDA-----SNTEKKPTAFFDCHMMVE-NP------EKWVDDFAKCGADQFTFHYEAT  108
                       +  E +        +M   NP      E+++++  + G D         
Sbjct  71   DSGVTVKGIFQALIEVREEVQIPFVLMTYLNPVLAFGKERFIENCMEAGVDGIIVPDLPY  130

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG--GQKFMEDM  166
            ++   +  L++   I     +   + ++ + ++    +  +      G     Q F +++
Sbjct  131  EEQDIIAPLLREANIALIPLVTVTSPIERIKKITSESEGFVYAVTVAGVTGVRQNFKDEI  190

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
               +E +++   HL +    G+  +   +      + +V G+          VI  ++ E
Sbjct  191  HSYLEKVKSHT-HLPVVAGFGISTKEHVEEMVTICDGVVVGS---------KVIELLENE  240

Query  227  VSKEL  231
              +E+
Sbjct  241  KREEI  245


>gi|73622018|sp|Q5KXV2|TRPA_GEOKA  Tryptophan synthase alpha chain
Length=268

 Score =  148 bits (375),  Expect = 1e-35, Method: Composition-based stats.
 Identities = 36/227 (15%), Positives = 70/227 (30%), Gaps = 20/227 (8%)

Query  2    VKPIIAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
              P+  P I+A D A          +  AGAD L + V    +   +  G  I  +  R+
Sbjct  6    NPPLFIPFIVAGDPAPDVTIDLALALEEAGADILELGV---PYSDPLADGPTIQRAAARA  62

Query  60   VPRPGDASNTEKKPTA------FFDCHM-MVENP------EKWVDDFAKCGADQFTFHYE  106
            +          +               +    NP      E +     + GAD       
Sbjct  63   LDGGMTLPKAIQLIGEMRKKGVNIPIILFTYYNPVLQLGEESFFALARENGADGVLIPDL  122

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF-MED  165
              ++   L +L +  G+     + P TS   +  +A      L      G  G +  + +
Sbjct  123  PFEESGPLRELGERFGLPLISLVAP-TSKQRIERIASAAQGFLYCVSSLGVTGVRETLPE  181

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
             +        +   + + V  G+         K   + +V G+++  
Sbjct  182  TLGDFLREVKRHSRVPVAVGFGISAPEQVAMLKEVCDGVVVGSALVQ  228


>gi|28380199|sp|Q8YE59|TRPA_BRUME  Tryptophan synthase alpha chain
Length=279

 Score =  148 bits (375),  Expect = 1e-35, Method: Composition-based stats.
 Identities = 40/260 (15%), Positives = 78/260 (30%), Gaps = 33/260 (12%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +P +    +  D            +  AGAD + + +    F   +  G  I  +  R++
Sbjct  17   RPALVTYFMGGDPDLETALKVMKALPKAGADVIELGM---PFSDPMADGPAIQAAGLRAL  73

Query  61   PRPGDASNTEKKPTAF------FDCHMM-------VENPEKWVDDFAKCGADQFTFHYEA  107
                  + T      F          MM       +   E+++ D    G D        
Sbjct  74   NAGQTLAKTLYMAAEFRKEDDTTPIVMMGYYNLIYIYGVERFLTDAKASGVDGLIVVDLP  133

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMED--  165
            ++    L       GI       P T    L ++  +    +      G  G    +   
Sbjct  134  SEMDAELCIPAMKAGINFIRLTTPTTDDKRLPKVLHNSSGFVYYVSMNGITGAAIADTAK  193

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAA-----------  214
            +   V  ++     L I V  G+       A    A+ +V GT++  A            
Sbjct  194  VGEAVRHIKKST-DLPICVGFGVKTPEQAAAIATHADGVVVGTAIVNAIAGELDEKGKAK  252

Query  215  -DPHDVISFMKEEVSKELRS  233
             DP    + +   +++ +R+
Sbjct  253  GDPVAAATRLVHALAESVRA  272


>gi|73621989|sp|Q73BQ6|TRPA_BACC1  Tryptophan synthase alpha chain
Length=258

 Score =  148 bits (374),  Expect = 2e-35, Method: Composition-based stats.
 Identities = 35/245 (14%), Positives = 86/245 (35%), Gaps = 29/245 (11%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K    P ++  D     L      +  AGA  + I +    F   +  G  I  + +R++
Sbjct  14   KKAFIPYVMGGDGGLEKLKERIRFLDEAGASIVEIGI---PFSDPVADGPTIQRAGKRAL  70

Query  61   PRPGDA-----SNTEKKPTAFFDCHMMVE-NP------EKWVDDFAKCGADQFTFHYEAT  108
                       +  E +        +M   NP      E+++++  + G D         
Sbjct  71   DSGVTVKGIFQALIEVRKEVQIPFVLMTYLNPVLAFGKEQFIENCIEAGVDGIIVPDLPY  130

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG--GQKFMEDM  166
            ++   +  L+++  I     +   + ++ + ++    +  +      G     Q F E++
Sbjct  131  EEQDIIAPLLRTANIALIPLVTVTSPIERIEKITSESEGFVYAVTVAGVTGVRQNFKEEI  190

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
               +E +++   HL +    G+  +   +      + +V G+          VI  ++ E
Sbjct  191  HSYLEKVKSHT-HLPVVAGFGISTKEHVEEMITICDGVVVGS---------KVIELLENE  240

Query  227  VSKEL  231
              +E+
Sbjct  241  KREEI  245


>gi|136372|sp|P13228|TRP_NEUCR  Tryptophan synthase
Length=708

 Score =  148 bits (374),  Expect = 2e-35, Method: Composition-based stats.
 Identities = 38/238 (15%), Positives = 71/238 (29%), Gaps = 22/238 (9%)

Query  15   FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKPT  74
                      +   GAD + + V    F   I  G  I T+   ++       +T +   
Sbjct  30   PEQTPDILLAMEKGGADVIELGV---PFTDPIADGPTIQTANTIALQHGVTLQSTLQMVR  86

Query  75   ------AFFDCHMM-VENP------EKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSK  121
                        +M   NP      E+ ++D  + G + F       ++ +   +L    
Sbjct  87   DARQRGLKAPVMLMGYYNPLLSYGEERLLNDCKEAGVNGFIIVDLPPEEAVSFRQLCTRG  146

Query  122  GIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--FMEDMMPKVETLRAKFPH  179
            G+     I P TS   +  L    D  + +    G  G       ++   +  ++    +
Sbjct  147  GLSYVPLIAPATSDARMRVLCQLADSFIYVVSRQGVTGASGTLNANLPELLARVKKYSGN  206

Query  180  LNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRDLL  237
                V  G+          A A+ +V G+ + T            EEV         L
Sbjct  207  KPAAVGFGVSTHDHFTQVGAIADGVVVGSMIITT--IQKAAKG--EEVKAVQEYCSYL  260


>gi|14423983|sp|Q9V1G9|TRPA_PYRAB  Tryptophan synthase alpha chain
Length=248

 Score =  148 bits (374),  Expect = 2e-35, Method: Composition-based stats.
 Identities = 38/243 (15%), Positives = 82/243 (33%), Gaps = 24/243 (9%)

Query  6    IAPSILASDFAN--LGCECHKVIN-AGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPR  62
            + P + A D +          +   +GA  + + +    F   I  G+ I  S  R++  
Sbjct  7    LIPYLTAGDPSAKATLRFLLAIEEYSGA--IELGI---PFSDPIADGKTIQQSHFRALKG  61

Query  63   PGDASNTEKKPTAF-----FDCHMM-VENP------EKWVDDFAKCGADQFTFHYEATQD  110
                 +       F         +M   NP       +++      G D           
Sbjct  62   GFKLEHAFNIVREFRKHSDVPIVLMTYYNPVFRVGLREFIGKAKDSGVDGMLIVDLPVMH  121

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDMMPK  169
                +++ + +GIK      P T  + L E+         ++++    G +  + +    
Sbjct  122  ASEFLEVAREEGIKTVFLAAPNTPDERLKEIDKASTGFVYLISLYGTTGARDKIPETAFN  181

Query  170  VETLRAKFPHLNIQVDGGLGK-ETIPKAAKAGANVIVAGTSVFT--AADPHDVISFMKEE  226
            +     +     + V  G+ K E +     AGAN +V G+++    A    +    ++E+
Sbjct  182  LLKRAKRICKNKVAVGFGVSKREHVEMLLNAGANGVVVGSALINIIAEHGENAEEKLREK  241

Query  227  VSK  229
            V +
Sbjct  242  VRE  244


>gi|116256441|sp|Q1XDA5|TRPA_PORYE  Tryptophan synthase alpha chain
Length=263

 Score =  148 bits (373),  Expect = 2e-35, Method: Composition-based stats.
 Identities = 31/227 (13%), Positives = 71/227 (31%), Gaps = 19/227 (8%)

Query  2    VKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +  + P I A D    + G     + + GAD + + +    +   +  G  I  +  R+
Sbjct  13   KQCALIPFITAGDPDLVSTGKALQILDSYGADIIELGL---PYSDPLADGPIIQEASNRA  69

Query  60   VPRPGDASNTEKKPTAF------FDCHMMVENP------EKWVDDFAKCGADQFTFHYEA  107
            + +  + +                       NP        ++   +  G          
Sbjct  70   LKQGINLNKILSMVKTVNMTIKAPIVLFTYYNPVLHLGINNFIYAISNAGIRGLLIPDLP  129

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF--MED  165
             ++  +++ +     I+    + P +S + + ++       + +    G  GQK      
Sbjct  130  IEESEYVISVCNLFNIELILLLAPTSSRERISKIIKRAPGCIYLVSTTGVTGQKSQLTSQ  189

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
            +    ET++       I   G    E I +      N IV G++   
Sbjct  190  LKELTETVKTMTNKSIILGFGISTTEQIKEIKGWNINGIVIGSAFVK  236


>gi|73622047|sp|Q5LV87|TRPA_SILPO  Tryptophan synthase alpha chain
Length=263

 Score =  148 bits (373),  Expect = 2e-35, Method: Composition-based stats.
 Identities = 42/250 (16%), Positives = 76/250 (30%), Gaps = 22/250 (8%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K      ++A D  F         +  AG D + + +    F   +  G  I  + +R++
Sbjct  16   KKAFVSYVMAGDPDFDTSLELVKGLPGAGVDIIELGL---PFTDPMADGPTIQLAGQRAL  72

Query  61   PRPGDASNTEKKPTAF------FDCHMM-VENP------EKWVDDFAKCGADQFTFHYEA  107
                    T    T F          MM   NP      ++++ D    G D        
Sbjct  73   DGGMTLQRTLDLATEFRKTDNTTPIVMMGYYNPIYSRGVDRFLADAKAAGIDGLIVVDLP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMM  167
             ++   L    ++ G+       P T    L  +  +    +      G  G    E   
Sbjct  133  PEEDSELCLPAQAAGLNFIRLATPTTDDKRLPRVLQNTSGFVYYVSITGITGSAEAEATD  192

Query  168  PKVETLR-AKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF---TAADPHDVISFM  223
               E  R      L + V  G+      +A  + A+  V G+++     A  P   +   
Sbjct  193  VGPEVARIKAATDLPVIVGFGINTPEKSRAIASVADGAVVGSAIVGQIGAGKPVAEVLAF  252

Query  224  KEEVSKELRS  233
             + +S    S
Sbjct  253  VKTLSDGAHS  262


>gi|73622029|sp|Q604P4|TRPA_METCA  Tryptophan synthase alpha chain
Length=267

 Score =  148 bits (373),  Expect = 2e-35, Method: Composition-based stats.
 Identities = 41/257 (15%), Positives = 83/257 (32%), Gaps = 29/257 (11%)

Query  2    VKPIIAPSILASDFAN--LGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +  + P I A D          H ++ AGAD + + V    F   +  G  I  +  R+
Sbjct  15   NRKALIPFITAGDPEPGFTVPVMHAMVEAGADVIELGV---PFSDPMADGPVIQKASERA  71

Query  60   VPRPGDASNTEKKPTAF------FDCHMMVE-------NPEKWVDDFAKCGADQFTFHYE  106
            +        T      F          +M           +++VD     G D       
Sbjct  72   LVHHMSLGKTLDLVAEFRRADRTTPIVLMGYLNPVECMGYQRFVDRAKDAGVDGVLTVDM  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFME--  164
              ++    V ++   G+     + P +S   +  +A      L      G  G   ++  
Sbjct  132  PPEEAGEFVPMLHRAGLDPIFLLAPNSSDARVQRMAALGRGYLYYVSLKGVTGASHLDLA  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTS----VFTAADPHDVI  220
            ++  ++  +R+    L I V  G+       A    A+ +V G++    +  A D  +  
Sbjct  192  EVESRIAHIRSLT-DLPIGVGFGVKNAETAAAIGRFADAVVVGSALVEKIAAAQDRPEQA  250

Query  221  SF----MKEEVSKELRS  233
                  +   + + L +
Sbjct  251  RKDIVDLLAVMRRALDA  267


>gi|73622003|sp|Q57AF2|TRPA_BRUAB  Tryptophan synthase alpha chain
Length=279

 Score =  147 bits (372),  Expect = 3e-35, Method: Composition-based stats.
 Identities = 41/260 (15%), Positives = 78/260 (30%), Gaps = 33/260 (12%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +P +    +  D            +  AGAD + + +    F   +  G  I  +  R++
Sbjct  17   RPALVTYFMGGDPDLETALKVMKALPKAGADVIELGM---PFSDPMADGPAIQAAGLRAL  73

Query  61   PRPGDASNTEKKPTAF------FDCHMM-------VENPEKWVDDFAKCGADQFTFHYEA  107
                  + T      F          MM       V   E+++ D    G D        
Sbjct  74   NAGQTLAKTLYMAAEFRKEDDTTPIVMMGYYNPIYVYGVERFLTDAKASGVDGLIVVDLP  133

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMED--  165
            ++    L       GI       P T    L ++  +    +      G  G    +   
Sbjct  134  SEMDAELCIPAMKAGINFIRLTTPTTDDKRLPKVLHNSSGFVYYVSMNGITGAAIADTAK  193

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAA-----------  214
            +   V  ++     L I V  G+       A    A+ +V GT++  A            
Sbjct  194  VGEAVRHIKKST-DLPICVGFGVKTPEQAAAIATHADSVVVGTAIVNAIAGELDEKGKVK  252

Query  215  -DPHDVISFMKEEVSKELRS  233
             DP    + +   +++ +R+
Sbjct  253  GDPVAAATRLVHALAESVRA  272


>gi|20140722|sp|Q98CN6|TRPA_RHILO  Tryptophan synthase alpha chain
Length=279

 Score =  146 bits (370),  Expect = 5e-35, Method: Composition-based stats.
 Identities = 39/260 (15%), Positives = 82/260 (31%), Gaps = 33/260 (12%)

Query  3    KPIIAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +P +    +  D            +  AG+D + + +    F   +  G  I  +  R++
Sbjct  17   RPALVTYFMGGDPDYDTSLSIMKALPGAGSDIIELGM---PFSDPMADGPAIQAAGLRAL  73

Query  61   PRPGDASNTEKKPTAF------FDCHMM-------VENPEKWVDDFAKCGADQFTFHYEA  107
                    T K  + F          +M       +   ++++ D    G D        
Sbjct  74   KGGQTLVKTLKMASEFRAGDNETPIVLMGYYNPIYIYGVDRFLKDALASGIDGLIVVDLP  133

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMED--  165
             +    L       GI       P T    L ++  +    +      G  G    +   
Sbjct  134  PEMDEELCIPALKAGINFIRLATPTTDDKRLPKVLQNTSGFVYYVSMTGITGSALADTGK  193

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA------------  213
            +   V  ++     L + V  G+      +   A A+ +V GT++  A            
Sbjct  194  VAAAVNRIKGHT-DLPVCVGFGVKTAEQARVIGANADGVVVGTAIVNAVANVLGPKGEKT  252

Query  214  ADPHDVISFMKEEVSKELRS  233
            ADP + ++ +   +++ +RS
Sbjct  253  ADPAEAVATLVSGLAQGVRS  272


>gi|73920965|sp|P42390|TRPA_MAIZE  Indole-3-glycerol phosphate lyase, chloroplast precursor (Indole 
synthase) (Tryptophan synthase alpha chain) (Benzoxazineless 
1)
Length=347

 Score =  146 bits (370),  Expect = 5e-35, Method: Composition-based stats.
 Identities = 35/242 (14%), Positives = 74/242 (30%), Gaps = 19/242 (7%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K    P I A D   A        +   GAD + + V           G  I  S+ R++
Sbjct  102  KTAFIPYITAGDPDLATTAEALRLLDGCGADVIELGV---PCSDPYIDGPIIQASVARAL  158

Query  61   PRPGDASNTEKKPTAFFD------CHMMVENPE--KWVDDFAKCGADQFTFHYEATQDPL  112
                      +               +    P   + + +  + G               
Sbjct  159  ASGTTMDAVLEMLREVTPELSCPVVLLSYYKPIMSRSLAEMKEAGVHGLIVPDLPYVAAH  218

Query  113  HLVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDMMPKVE  171
             L    K+  ++      P    D + E+         +++V    G +  +   +  + 
Sbjct  219  SLWSEAKNNNLELVLLTTPAIPEDRMKEITKASEGFVYLVSVNGVTGPRANVNPRVESLI  278

Query  172  TLRAKFPHLNIQVDGGL-GKETIPKAAKAGANVIVAGTSVFT----AADPHDVISFMKEE  226
                K  +  + V  G+   E + + A+ GA+ ++ G+++      AA P   +  ++E 
Sbjct  279  QEVKKVTNKPVAVGFGISKPEHVKQIAQWGADGVIIGSAMVRQLGEAASPKQGLRRLEEY  338

Query  227  VS  228
              
Sbjct  339  AR  340


>gi|24638311|sp|Q8U094|TRPA_PYRFU  Tryptophan synthase alpha chain
Length=248

 Score =  146 bits (370),  Expect = 5e-35, Method: Composition-based stats.
 Identities = 35/248 (14%), Positives = 74/248 (29%), Gaps = 22/248 (8%)

Query  2    VKPIIAPSILASDFAN--LGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
                + P + A D            +    A  + + +    F   I  G+ I  S  R+
Sbjct  3    KDGSLIPYLTAGDPDKQSTLNFLLALDEY-AGAIELGI---PFSDPIADGKTIQESHYRA  58

Query  60   VPRPGDASNTEKKPTAFFD------CHMMVENPEK------WVDDFAKCGADQFTFHYEA  107
            +               F          M   NP        ++ +    G D        
Sbjct  59   LKNGFKLREAFWIVKEFRRHSSTPIVLMTYYNPIYRAGVRNFLAEAKASGVDGILVVDLP  118

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAP-HLDMALVMTVEPGFGGQKFMEDM  166
                    ++ + +GIK      P T  + L  +         ++++    G ++ +   
Sbjct  119  VFHAKEFTEIAREEGIKTVFLAAPNTPDERLKVIDDMTTGFVYLVSLYGTTGAREEIPKT  178

Query  167  -MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA--ADPHDVISFM  223
                +   +    +      G   +E +    K GAN +V G+++         +   F+
Sbjct  179  AYDLLRRAKRICRNKVAVGFGVSKREHVVSLLKEGANGVVVGSALVKIIGEKGREATEFL  238

Query  224  KEEVSKEL  231
            K++V + L
Sbjct  239  KKKVEELL  246


>gi|73621987|sp|Q5P1I9|TRPA_AZOSE  Tryptophan synthase alpha chain
Length=271

 Score =  146 bits (369),  Expect = 6e-35, Method: Composition-based stats.
 Identities = 34/250 (13%), Positives = 76/250 (30%), Gaps = 27/250 (10%)

Query  6    IAPSILASDFAN--LGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            + P I A D A        + ++  GAD + + V    F   +  G  I  +  R++   
Sbjct  19   LIPFITAGDPAPELTVPLMNALVEGGADIIELGV---PFSDPMADGPTIQRASERALANG  75

Query  64   GDASNTEKKPTAF------FDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEATQD  110
                        F          +M           E++V    +   D         ++
Sbjct  76   MTLRRVLDTVREFRTGNAETPVVLMGYANPIEAMGVERFVSAAREAQVDGVLIVDYPPEE  135

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--EDMMP  168
                 +  K  G+     + P ++     ++A      +      G  G   +  +++  
Sbjct  136  CESFARAAKDAGLDPIFLLAPTSTEQRFRDVARVGSGYIYYVSLKGVTGSATLDFDEVAA  195

Query  169  KVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADP------HDVISF  222
            ++  +RA+     + V  G+      +     A+ +V G+ +    +          ++ 
Sbjct  196  RIPQIRAQVGM-PVGVGFGIRDAESARRIGEVADAVVIGSRIIEEIERSPRDRLAANVTA  254

Query  223  MKEEVSKELR  232
               EV   L 
Sbjct  255  FLREVRTALD  264


>gi|136253|sp|P19867|TRPA_BACST  Tryptophan synthase alpha chain
Length=269

 Score =  145 bits (367),  Expect = 1e-34, Method: Composition-based stats.
 Identities = 37/228 (16%), Positives = 72/228 (31%), Gaps = 22/228 (9%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
              P+  P I+A D            +  AGAD L + V    +   +  G  I  +  R+
Sbjct  7    NPPLFIPFIVAGDPSPEVTVDLALALEEAGADLLELGV---PYSDPLADGPTIQRAAARA  63

Query  60   V------PRPGDASNTEKKPTAFFDCHM-MVENP------EKWVDDFAKCGADQFTFHYE  106
            +      P+        +K        +    NP      E +     + GA+       
Sbjct  64   LAGNMTLPKAIHLVAEMRKKGVTIPIILFTYYNPVLQLGEESFFALARENGANGVLIPDL  123

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF--ME  164
              ++   L +L +   +     + P TS   +  +A      L      G  G +    E
Sbjct  124  PFEESGPLRELGERFDLPLISLVAP-TSKQRIERIASVAQGFLYCVSSLGVTGMRETLPE  182

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
             +   V  ++     + + V  G+         K   + +V G+++  
Sbjct  183  SLGDFVSEVKRH-SRVPVAVGFGISTPEQVAMLKEVCDGVVIGSALVQ  229


>gi|464911|sp|P34816|TRPA_PSESY  Tryptophan synthase alpha chain
Length=269

 Score =  145 bits (367),  Expect = 1e-34, Method: Composition-based stats.
 Identities = 42/259 (16%), Positives = 81/259 (31%), Gaps = 28/259 (10%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +  +   + A D            +  AGAD + + +    F   +  G  I  +  R+
Sbjct  15   NRAALVTFVTAGDPGYDTSLAILKGLPAAGADVIELGM---PFTDPMADGPAIQLANIRA  71

Query  60   VPRPGDASNTEKKPTAF------FDCHMM-VENPE------KWVDDFAKCGADQFTFHYE  106
            +    +   T +    F          +M   NP       K++ D  + G D       
Sbjct  72   LEAKQNLLKTLQMVREFRKGNNDTPLVLMGYFNPIHKYGVPKFIADAKEAGVDGLIVVDM  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPH-LDMALVMTVEP-GFGGQKFME  164
              +    L    ++ GI       P T    L  +          ++V      G   +E
Sbjct  132  PPEHNGELCDPAQAAGIDFIRLTTPTTDDVRLPTVLNGSSGFVYYVSVAGVTGAGAATLE  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTS----VFTAADPHDVI  220
             +   V  LR     L I +  G+       A    A+ +V G++    +  A +    I
Sbjct  192  HVEEAVARLRRHT-DLPISIGFGIRTPEQAAAIARLADGVVVGSALIDHIANAKNDQQAI  250

Query  221  S---FMKEEVSKELRSRDL  236
                 +   +S+ +R+  +
Sbjct  251  DGVLGLCAALSEGVRNASV  269


>gi|7676165|sp|O27697|TRPA_METTH  Tryptophan synthase alpha chain
Length=270

 Score =  145 bits (366),  Expect = 1e-34, Method: Composition-based stats.
 Identities = 30/241 (12%), Positives = 76/241 (31%), Gaps = 24/241 (9%)

Query  6    IAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
              P ++A D            +++AGAD L +      F   I  G  +  +  R++   
Sbjct  21   FVPFVVAGDPDMETSLEIIRTLVDAGADALEVGF---PFSDPIADGTSVQGADLRALRAG  77

Query  64   GDASNTEKKPT-----AFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEATQDP  111
                   +              ++V          +++    A+ G           ++ 
Sbjct  78   MTTEKCFQLIERVREFTSIPIGLLVYYNLIYRMGVDEFYRRAAEAGVTGILAADLPPEEA  137

Query  112  LHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF--MEDMMPK  169
               ++  +   I     + P T  + L  ++        +    G  G +    +  +  
Sbjct  138  SDALRAAEKYDIDQIFIVAPTTGSERLKRISEVSSGFHYLVSVMGVTGARSRVEDATIEL  197

Query  170  VETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF-----TAADPHDVISFMK  224
            ++ ++A+     +   G    E +     AGA+ ++ G+++         D   ++  + 
Sbjct  198  IKRVKAEGSLPVMVGFGVSRPEHVRMLRDAGADGVIVGSAIIDVISGNLGDRELMLQRIH  257

Query  225  E  225
            E
Sbjct  258  E  258


>gi|136262|sp|P14637|TRPA_METVO  Tryptophan synthase alpha chain
Length=284

 Score =  145 bits (365),  Expect = 2e-34, Method: Composition-based stats.
 Identities = 36/247 (14%), Positives = 75/247 (30%), Gaps = 25/247 (10%)

Query  4    PIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVP  61
            PI+   +++ D          + +       + + +    F   I  G  I  +  RS+ 
Sbjct  24   PILVSFLVSGDPNIEATLKFMNALDEY-CGVIELGI---PFSDPIADGSTIQEANVRSLS  79

Query  62   RPGDASNTEKKPTAF-----FDCHMM-VENP------EKWVDDFAKCGADQFTFHYEATQ  109
                   +      F         +M   NP      E +V    + GA+          
Sbjct  80   NGYKIHQSFDVLREFRKFSDTPVVLMTYYNPIYKRGIENFVIQAKEAGANGLIIVDLPLD  139

Query  110  DPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--FMEDMM  167
            +      + K   +     + P T  + L        + L +    G  G +  F +   
Sbjct  140  EAEQYRAICKKHDMGTVFLVAPNTPDERLMYSDEASTLFLYVISTFGITGARGSFEKMTF  199

Query  168  PKVETLRAKFPHLNIQVDGGL-GKETIPKAAKAGANVIVAGTSVFTAA----DPHDVISF  222
              +   +       + V  G+   E   K  + GA+ ++ G++         D ++ I  
Sbjct  200  EFIARAKNLCDKNKLYVGFGISNGEHAEKIIENGADGVIVGSAFVDIIKEYGDSNETIYK  259

Query  223  MKEEVSK  229
            +KE   +
Sbjct  260  LKELARE  266


>gi|73622030|sp|Q6LYI9|TRPA_METMP  Tryptophan synthase alpha chain
Length=258

 Score =  145 bits (365),  Expect = 2e-34, Method: Composition-based stats.
 Identities = 35/256 (13%), Positives = 78/256 (30%), Gaps = 27/256 (10%)

Query  1    MVKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRR  58
            M KP++   +++ D            +    +  + + +    F   +  G  I  +  R
Sbjct  1    MNKPVLVSFLVSGDPNPDATLKFMKTLDKY-SGVIELGI---PFSDPVADGPTIQAADVR  56

Query  59   SVPRPGDASNTEKKPTAF-----FDCHMM-VENP------EKWVDDFAKCGADQFTFHYE  106
            S+      + + +    F         +M   NP      E +V    + GA+       
Sbjct  57   SLSNNFKIAKSFEVLKEFRKESDTPVILMTYYNPVYKRGIENFVIQAKEAGANGLIIVDL  116

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--FME  164
              Q+     K+ K   +       P T  + L          L +    G  G +  F +
Sbjct  117  PLQEATEYRKICKKHEMGTVFLAAPNTPEERLKISDEASTEFLYLISTFGITGARDTFEQ  176

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTS----VFTAADPHDV-  219
                 ++  R           G           + GA+ ++ G++    +    D  +  
Sbjct  177  MTFDFIKRARTTCKGKICVGFGISKGSHAESLIEQGADGVIVGSAFVDIIKNYGDSKEAL  236

Query  220  --ISFMKEEVSKELRS  233
              +  + +E+S+ +  
Sbjct  237  VKLEELAKELSEGIDK  252


>gi|28380195|sp|Q8UJA9|TRPA_AGRT5  Tryptophan synthase alpha chain
Length=279

 Score =  144 bits (364),  Expect = 2e-34, Method: Composition-based stats.
 Identities = 37/227 (16%), Positives = 69/227 (30%), Gaps = 19/227 (8%)

Query  2    VKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +P +    +  D  F         +  AGAD + + +    F   +  G  I  + +R+
Sbjct  16   NRPALITYFMGGDPDFQTSLGIMKALPEAGADVIELGM---PFSDPMADGPAIQLAGQRA  72

Query  60   VPRPGDASNTEKKPTAF------FDCHMM-------VENPEKWVDDFAKCGADQFTFHYE  106
            +        T      F          MM       +   EK++DD    G D       
Sbjct  73   LKGGQTLKTTLDLAREFRKQDNATPIVMMGYYNPIYIYGVEKFLDDAIASGIDGLIVVDL  132

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPH-LDMALVMTVEPGFGGQKFMED  165
              +    L     ++GI       P T    L  +  +       +++    G       
Sbjct  133  PPEMDDELCIPALARGINFIRLATPTTDGKRLPAVLKNTSGFVYYVSMNGITGSALPDPS  192

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
            ++            L + V  G+      KA  A A+ +V G+++  
Sbjct  193  LISGAVGRIKAHTELPVCVGFGVKTADHAKAIGAVADGVVVGSAIVN  239


>gi|20140676|sp|Q92TC8|TRPA_RHIME  Tryptophan synthase alpha chain
Length=279

 Score =  144 bits (364),  Expect = 2e-34, Method: Composition-based stats.
 Identities = 38/226 (16%), Positives = 72/226 (31%), Gaps = 19/226 (8%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +P++    +  D  F         +  AGAD + + V    F   +  G  I  + +R++
Sbjct  17   RPVLVTYFMGGDPDFDTSLAIMKALRQAGADIIELGV---PFSDPMADGPAIQLAGQRAL  73

Query  61   PRPGDASNTEKKPTAF------FDCHMM-------VENPEKWVDDFAKCGADQFTFHYEA  107
                  + T +    F          +M       +   E+++ D  + G D        
Sbjct  74   KAGQSLAKTLELARLFRAEDQRTPIVLMGYYNPIYIYGVERFLADALEAGVDGLIVVDLP  133

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMM  167
             +    L      KGI       P T    L ++  +    +      G  G    +  +
Sbjct  134  PEMDDELCIPALEKGISFIRLATPTTDDRRLPKVLENTSGFVYYVSMTGITGSALPDPSL  193

Query  168  PKVETLR-AKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
                  R      L + V  G+      +A  A A+ +V GT++  
Sbjct  194  IAGAVARIKAHTPLPVCVGFGVKTADHARAIGASADGVVVGTAIVN  239


>gi|73621992|sp|Q5LBZ2|TRPA_BACFN  Tryptophan synthase alpha chain
 gi|73621993|sp|Q64SX3|TRPA_BACFR  Tryptophan synthase alpha chain
Length=263

 Score =  144 bits (364),  Expect = 3e-34, Method: Composition-based stats.
 Identities = 32/233 (13%), Positives = 68/233 (29%), Gaps = 22/233 (9%)

Query  15   FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKP-  73
                      +   G + + I +    F   +  G  I  +  +++          ++  
Sbjct  27   LEGTTEVIRTLEKHGVNMIEIGI---PFSDPMADGMVIQNAATQALRNGMSLRLLFEQLH  83

Query  74   ----TAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEATQDPLH-LVKLIKSK  121
                       +M           + +    A+CG D         +D       + +  
Sbjct  84   DIRRDVKIPLILMGYLNPIMQFGFDNFCRQCAECGIDGVIIPDLPFKDYQEHFRTIAERY  143

Query  122  GIKAACAIKPGTSVDVLFELAPHLDMALVM--TVEPGFGGQKFMEDMMPKVETLRAKFPH  179
             +K    I P TS + + E+  H D  + M  +       Q F        + +      
Sbjct  144  DVKVIMLITPETSEERVREIDEHTDGFIYMVSSAATTGAQQDFDGQKRAYFKKIEKMNLR  203

Query  180  LNIQVDGGLGKETIPKAAKAGANVIVAGTSVF----TAADPHDVISFMKEEVS  228
                V  G+  E   +AA   A+  + G+          +P   I+ +K  ++
Sbjct  204  NPRMVGFGISNEATFRAACENASGAIIGSRFVTLLHEEKNPEKAITRLKAILN  256


>gi|32130302|sp|Q8KZ93|TRPA_BACNA  Tryptophan synthase alpha chain
Length=267

 Score =  144 bits (363),  Expect = 3e-34, Method: Composition-based stats.
 Identities = 39/251 (15%), Positives = 81/251 (32%), Gaps = 29/251 (11%)

Query  4    PIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVP  61
             +  P I A D            +  AGA  L + V    +   +  G  I  + +R++ 
Sbjct  11   KLFIPFITAGDPVPEVSIELAKSLQKAGATALELGVA---YSDPLADGPVIQRASKRALD  67

Query  62   RPGDASNTEK------KPTAFFDCHM-MVENP------EKWVDDFAKCGADQFTFHYEAT  108
            +  +     +      K        +    NP      E +     +   D         
Sbjct  68   QGMNIVKAIELGGEMKKNGVNIPIILFTYYNPVLQLNKEYFFALLQENHIDGLLVPDLPL  127

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--FMEDM  166
            ++   L +  KS  +     + P TS   L  +    +  +      G  G +  F   +
Sbjct  128  EESNSLQEECKSHEVTYISLVAP-TSESRLKTIIEQAEGFVYCVSSLGVTGVRNEFNSSV  186

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
             P + T++     + + V  G+            ++ +V G+++         I  +K+ 
Sbjct  187  YPFIRTVKNL-STVPVAVGFGISNREQVIKMNEISDGVVVGSALVRK------IEELKDR  239

Query  227  -VSKELRSRDL  236
             +S E R++ L
Sbjct  240  LISAETRNQAL  250


>gi|136254|sp|P07601|TRPA_BACSU  Tryptophan synthase alpha chain
Length=267

 Score =  144 bits (363),  Expect = 3e-34, Method: Composition-based stats.
 Identities = 39/251 (15%), Positives = 81/251 (32%), Gaps = 29/251 (11%)

Query  4    PIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVP  61
             +  P I A D            +  AGA  L + V    +   +  G  I  + +R++ 
Sbjct  11   KLFIPFITAGDPVPEVSIELAKSLQKAGATALELGVA---YSDPLADGPVIQRASKRALD  67

Query  62   RPGDASNTEK------KPTAFFDCHM-MVENP------EKWVDDFAKCGADQFTFHYEAT  108
            +  +     +      K        +    NP      E +     +   D         
Sbjct  68   QGMNIVKAIELGGEMKKNGVNIPIILFTYYNPVLQLNKEYFFALLRENHIDGLLVPDLPL  127

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--FMEDM  166
            ++   L +  KS  +     + P TS   L  +    +  +      G  G +  F   +
Sbjct  128  EESNSLQEECKSHEVTYISLVAP-TSESRLKTIIEQAEGFVYCVSSLGVTGVRNEFNSSV  186

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
             P + T++     + + V  G+            ++ +V G+++         I  +K+ 
Sbjct  187  YPFIRTVKNL-STVPVAVGFGISNREQVIKMNEISDGVVVGSALVRK------IEELKDR  239

Query  227  -VSKELRSRDL  236
             +S E R++ L
Sbjct  240  LISAETRNQAL  250


>gi|20140887|sp|Q9PDK3|TRPA_XYLFA  Tryptophan synthase alpha chain
Length=268

 Score =  143 bits (362),  Expect = 4e-34, Method: Composition-based stats.
 Identities = 41/255 (16%), Positives = 81/255 (31%), Gaps = 28/255 (10%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  + P I A D          H ++ AGAD + + V    F   +  G  I  S  R++
Sbjct  16   RKALIPFITAGDPSLEAAVPVMHALVRAGADVIELGV---PFSDPMADGPVIQHSSERAL  72

Query  61   PRPGDAS------NTEKKPTAFFDCHMM-------VENPEKWVDDFAKCGADQFTFHYEA  107
             R    +      +  ++  A     +M       +    ++      CG D        
Sbjct  73   QRGVGLAYVLQTVDVFRQSDAVTPVVLMGYLNPLEIYGIARFTQHAVACGVDGVLLVDLP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMED--  165
             ++   +  +  + G+       P TS   L  L+      L      G  G   ++   
Sbjct  133  PEEADEIRPIFSAAGLALIVLASPTTSASRLARLSGVAQGYLYYVSFSGVTGADRLDAQS  192

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF----TAADPHDVIS  221
               ++  LRA+   + + V  G+            A+ +V G+++      A D      
Sbjct  193  AGDRLRGLRAQT-QVPVVVGFGIRDAASAAVMAVDADGVVVGSALVTALSDAPDVDTACR  251

Query  222  ---FMKEEVSKELRS  233
                    + + L +
Sbjct  252  RADAFLAPLRQALDA  266


>gi|73622012|sp|Q83CG2|TRPA_COXBU  Tryptophan synthase alpha chain
Length=267

 Score =  143 bits (362),  Expect = 4e-34, Method: Composition-based stats.
 Identities = 38/227 (16%), Positives = 70/227 (30%), Gaps = 19/227 (8%)

Query  2    VKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
              P     + A D            +   G + L + V    F   +  G  I  +  R+
Sbjct  10   KSPAYVAYLTAGDGGLERSLESLLALAKGGVNILEVGV---PFSDPVADGPVIQEASIRA  66

Query  60   VPRPGDASNTEKKPTAF-----FDCHM-MVENP-----EKWVDDFAKCGADQFTFHYEAT  108
            + +     +     T+F         +    NP     +K        G D         
Sbjct  67   LAQGTTLHDVLTLITSFRQHSEIPIILFTYFNPLLAAGDKIYQQMKSAGVDGCLVVDLPV  126

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF--MEDM  166
            ++    +   K+  I     I P T+ + L ++  H +  L     PG  G +    E+ 
Sbjct  127  EEAAPHLTACKTAKIAPILLISPSTTQERLKKINEHGEGMLYYVCRPGTTGVRATLPENF  186

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA  213
              K+  +++    L I    G+    +   A   A+  V G+    A
Sbjct  187  PAKMNQIKSMT-SLPIVTGFGIANRKMAAQALQYADGFVIGSLFVKA  232


>gi|73621997|sp|Q8AAD8|TRPA_BACTN  Tryptophan synthase alpha chain
Length=256

 Score =  143 bits (362),  Expect = 4e-34, Method: Composition-based stats.
 Identities = 38/248 (15%), Positives = 74/248 (29%), Gaps = 24/248 (9%)

Query  2    VKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             K I++    A +            +   G   + + +    F   +  G  I  +  ++
Sbjct  12   KKDILSIYFCAGNPTLDGTVNVIRTLEKHGVSMIEVGI---PFSDPMADGIVIQNAATQA  68

Query  60   VPRPGDASNTEKKPT-----AFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEA  107
            +          ++              M           E +     +CG D        
Sbjct  69   LRNGMSLKILFEQLRNIRQEVSIPLVFMGYLNPIMQFGFENFCRKCVECGIDGVIIPDLP  128

Query  108  TQDPLHLVKLIKS-KGIKAACAIKPGTSVDVLFELAPHLDMALVM--TVEPGFGGQKFME  164
             +D     ++I    GIK    I P TS + + E+  H D  + M  +       Q F E
Sbjct  129  FRDYQDHYRIIAERYGIKVIMLITPETSEERVREIDAHTDGFIYMVSSAATTGAQQDFNE  188

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF----TAADPHDVI  220
                  + +        + V  G+  +   +AA   A+  + G+          DP   I
Sbjct  189  QKRAYFKKIEDMNLRNPLMVGFGISNKATFQAACEHASGAIIGSRFVTLLEEEKDPEKAI  248

Query  221  SFMKEEVS  228
              +K+ + 
Sbjct  249  LKLKDALK  256


>gi|73622036|sp|Q7N485|TRPA_PHOLL  Tryptophan synthase alpha chain
Length=268

 Score =  143 bits (361),  Expect = 5e-34, Method: Composition-based stats.
 Identities = 35/250 (14%), Positives = 72/250 (28%), Gaps = 25/250 (10%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D            +I  GAD L + +    F   +  G  I  +  R+
Sbjct  15   KQGAFVPFVTLGDPTPELSLKIIDALITGGADALELSI---PFSDPLADGPTIQNANLRA  71

Query  60   V------PRPGDASNTEKKPTAFFDC-HMMVEN------PEKWVDDFAKCGADQFTFHYE  106
                       +     +          +M  N       +++         D       
Sbjct  72   FSSNVTPTLCFELLTKIRAKYPDIPIGLLMYANLVFHHGIDEFYRRCKDTDIDSVLVADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG-GQKFMED  165
               +           GI       P    ++L E+A +      +    G    ++  E 
Sbjct  132  PMSESRPFRTAAMKHGIAPIFICPPDAEDELLREIASYGRGYTYLLSRAGVTGIERRGEK  191

Query  166  MMP-KVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAAD-----PHDV  219
             +   V  LR       +Q  G    + + +   +GA   ++G+++    +     P  +
Sbjct  192  PLNHLVNKLREYHAAPPLQGFGISEPKQVKETLASGAAGAISGSAIVKIIEENLSQPEIM  251

Query  220  ISFMKEEVSK  229
            +  + E VSK
Sbjct  252  LKELTEFVSK  261


>gi|136264|sp|P11081|TRPA_PSEPU  Tryptophan synthase alpha chain
Length=269

 Score =  143 bits (361),  Expect = 5e-34, Method: Composition-based stats.
 Identities = 39/239 (16%), Positives = 69/239 (28%), Gaps = 21/239 (8%)

Query  6    IAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            +   + A D            +  AGAD + + +    F   +  G  I  +  R++   
Sbjct  19   LVTFVTAGDPGYDASLQILKGLPAAGADVIELGM---PFTDPMADGVAIQLATLRALEAG  75

Query  64   GDASNTEKKPTAF------FDCHMM-VENP------EKWVDDFAKCGADQFTFHYEATQD  110
               + T +    F          +M   NP      EK+V +  + G D         + 
Sbjct  76   QTLAKTLQMVREFRVDNHTTPIVLMGYYNPIHRFGVEKFVAEAKQAGVDGLIIVDLPPEH  135

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFMEDMMP  168
               L    ++ GI       P T    L  +       +      G  G      E +  
Sbjct  136  DAELATPAQAAGIDFIRLTTPTTDDARLPRVLERSSGFVYYVSVAGVTGAGSATTEHVTE  195

Query  169  KVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEV  227
             +  LR     L I V  G+            A+ +V G+++               +V
Sbjct  196  AIARLRRHT-DLPISVGFGIRTPEQAANIARLADGVVVGSALVDKIAQATSADQAVNDV  253


>gi|38258804|sp|Q8NWU1|TRPA_STAAW  Tryptophan synthase alpha chain
 gi|56749712|sp|Q6G9I6|TRPA_STAAS  Tryptophan synthase alpha chain
 gi|71153358|sp|Q5HG46|TRPA_STAAC  Tryptophan synthase alpha chain
Length=242

 Score =  143 bits (361),  Expect = 6e-34, Method: Composition-based stats.
 Identities = 37/249 (14%), Positives = 83/249 (33%), Gaps = 23/249 (9%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M K  I P I+ +   +L      +   GAD + I V    F   +  G  I+ + ++++
Sbjct  1    MTKLFI-PYIMGNK--DLIENATLLSENGADIIEIGV---PFSDPVADGPVIMEAGQQAI  54

Query  61   PRPGDASNTEKKPTAFFD------CHMMVENP------EKWVDDFAKCGADQFTFHYEAT  108
             +         +     D        M   N       + + +     G           
Sbjct  55   KQGITIDYIFNQLEKHGDQIKCNYVLMTYYNIICHYGEQAFFEKCRDTGVYGLIIPDLPY  114

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFMEDM  166
            +    L +     G+K    +   T    + ++  H +  +         GQ   F  ++
Sbjct  115  ELSQRLKQQFSHYGVKIISLVAMTTDDKRIKDIVSHAEGFIYTVTMNATTGQNGAFHPEL  174

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT--AADPHDVISFMK  224
              K+E+++A   ++ +    G+         K  A+ IV G+ +     ++  + I    
Sbjct  175  KRKIESIKA-IANVPVVAGFGIRTPQHVADIKEVADGIVIGSEIVKRFKSNTREEIIKYL  233

Query  225  EEVSKELRS  233
            + + + L +
Sbjct  234  QSIQQTLNN  242


>gi|28380181|sp|Q8PJ29|TRPA_XANAC  Tryptophan synthase alpha chain
Length=268

 Score =  143 bits (361),  Expect = 6e-34, Method: Composition-based stats.
 Identities = 38/255 (14%), Positives = 71/255 (27%), Gaps = 29/255 (11%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  + P I A D          H ++ AGAD + + V    F   +  G  I  S  R++
Sbjct  16   RKALIPFITAGDPSLEATVPVMHALVRAGADVIELGV---PFSDPMADGPTIQRSSERAL  72

Query  61   PRPGDASNTEKKPTAF------FDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEA  107
             R    +   +    F          +M            ++ +     G D        
Sbjct  73   ARGAGLAYVLEAVHEFRREDATTPVVLMGYLNPIEIHGTRRFAEAAVAAGVDGVLLVDLP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM---E  164
             ++      +    G+       P TS   L  L       L      G  G   +    
Sbjct  133  PEEAGETRTIFTEVGLALIALASPTTSEQRLDMLCSTAQGYLYYVSFAGVTGASNLLDTH  192

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA-------ADPH  217
                ++  LR +     +    G+       A    A+ +V G+++  A           
Sbjct  193  AASDRLRQLRRRAGA-PVVAGFGIKDAASAAAMAVDADGVVVGSALVAALAEVNDVRSAR  251

Query  218  DVISFMKEEVSKELR  232
            +        + + L 
Sbjct  252  ERAEAFLAPLRQALD  266


>gi|28380186|sp|Q8R9N0|TRPA_THETN  Tryptophan synthase alpha chain
Length=262

 Score =  143 bits (360),  Expect = 7e-34, Method: Composition-based stats.
 Identities = 36/252 (14%), Positives = 82/252 (32%), Gaps = 28/252 (11%)

Query  3    KPIIAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K  +   I A D            +  AGAD + + +    +   +  G  I  S +R++
Sbjct  16   KKALITFITAGDPDIDTTYDIVLALEEAGADIIELGI---PYSDPLADGPTIQASSQRAL  72

Query  61   PRPGDASNTEKKP-----TAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEAT  108
             +     +           +      +V          EK+++D    G D         
Sbjct  73   AKGIKIKDIMDLVMRIREKSDIPIVYLVYYNSVFKYGIEKFLEDSKNAGVDGLIIPDLPL  132

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF--MEDM  166
            ++   ++ +     I     + P TS + +  +  +    +      G  G +     D+
Sbjct  133  EERKEVLDVADKYEIYLIPLVAP-TSKERIKGITENGKGFVYCVTLTGVTGAREEITTDL  191

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAA----DPHDVISF  222
               +  + +          G  G E   K  K+ ++ IV G+++        +  +++  
Sbjct  192  EEYMRLVSSYTSMPKALGFGISGPEMARK-LKSLSDGIVVGSAIVERIAKGYNRCEMLKE  250

Query  223  MKE---EVSKEL  231
            +KE    + + L
Sbjct  251  VKEFVLSLREVL  262


>gi|54039758|sp|P66983|TRPA_STAAN  Tryptophan synthase alpha chain
 gi|54042262|sp|P66982|TRPA_STAAM  Tryptophan synthase alpha chain
Length=242

 Score =  143 bits (360),  Expect = 8e-34, Method: Composition-based stats.
 Identities = 37/249 (14%), Positives = 83/249 (33%), Gaps = 23/249 (9%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M K  I P I+ +   +L      +   GAD + I V    F   +  G  I+ + ++++
Sbjct  1    MTKLFI-PYIMGNK--DLIENATLLSENGADIIEIGV---PFSDPVADGPVIMEAGQQAI  54

Query  61   PRPGDASNTEKKPTAFFD------CHMMVENP------EKWVDDFAKCGADQFTFHYEAT  108
             +         +     D        M   N       + + +     G           
Sbjct  55   KQGITIDYIFNQLEKHGDQIKCNYVLMTYYNIICHYGEQAFFEKCRDTGVYGLIIPDLPY  114

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFMEDM  166
            +    L +     G+K    +   T    + ++  H +  +         GQ   F  ++
Sbjct  115  ELSQRLKQQFSHYGVKIISLVAMTTDDKRIKDIVSHAEGFIYTVTMNATTGQNGAFHPEL  174

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT--AADPHDVISFMK  224
              K+E+++A   ++ +    G+         K  A+ IV G+ +     ++  + I    
Sbjct  175  KRKIESIKA-IANVPVVAGFGIRTPQHVADIKEVADGIVIGSEIVKRFKSNTREEIIRYL  233

Query  225  EEVSKELRS  233
            + + + L +
Sbjct  234  QSIQQTLNN  242


>gi|38258744|sp|Q88RP7|TRPA_PSEPK  Tryptophan synthase alpha chain
Length=269

 Score =  142 bits (359),  Expect = 8e-34, Method: Composition-based stats.
 Identities = 37/239 (15%), Positives = 66/239 (27%), Gaps = 21/239 (8%)

Query  6    IAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            +   + A D            +  AGAD + + +    F   +  G  I  +  R++   
Sbjct  19   LVTFVTAGDPGYDASLQILKGLPAAGADVIELGM---PFTDPMADGVAIQLATLRALEAG  75

Query  64   GDASNTEKKPTAF------FDCHMM-VENP------EKWVDDFAKCGADQFTFHYEATQD  110
                 T +    F          +M   NP      + +V    + G D         + 
Sbjct  76   QTLVKTLQMVREFRVDNQTTPIVLMGYYNPIHRFGVDTFVTQAKEAGVDGLIIVDLPPEH  135

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFMEDMMP  168
               L    ++ GI       P T    L  +       +      G  G      E +  
Sbjct  136  DAELATPAQAAGIDFIRLTTPTTDDARLPRVLERSSGFVYYVSVAGVTGAGSATTEHVTE  195

Query  169  KVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEV  227
             +  LR     L I V  G+            A+ +V G+++               +V
Sbjct  196  AIARLRRHT-DLPISVGFGIRTPEQAANIARLADGVVVGSALVDKIAQAKSADQAVTDV  253


>gi|51701892|sp|Q8SRP6|RPE_ENCCU  Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) 
(PPE) (RPE)
Length=217

 Score =  142 bits (359),  Expect = 8e-34, Method: Composition-based stats.
 Identities = 68/226 (30%), Positives = 100/226 (44%), Gaps = 21/226 (9%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M+K  I  SIL  +F NL  E  ++   G   +H+DVMD  FV NIT G  I+  +    
Sbjct  5    MLKKRIGISILDCNFGNLEEELGELKRNGVTNIHLDVMDTTFVKNITFGPCIINRILEH-  63

Query  61   PRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKS  120
                            FD HMMVE+P   +           T H E       + + ++ 
Sbjct  64   -------------DFVFDVHMMVESPLDIIMQIDLERVSLVTIHSEVCDKAG-VAEYLRK  109

Query  121  KGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHL  180
            + +    A+ P T VD         D  L+M+V+PGFGGQKF E+ + KVE +R     +
Sbjct  110  RNVLFGIALNPETQVDDAE--MRSADFVLIMSVKPGFGGQKFQEECLAKVEEVRRYGKMV  167

Query  181  NIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
             I  DGG+    I +    GA+  V G+  F + D    +  + +E
Sbjct  168  GI--DGGIEMSNIGRI--TGADYAVVGSGYFRSGDRKKFLRDITDE  209


>gi|32130277|sp|Q87DR8|TRPA_XYLFT  Tryptophan synthase alpha chain
Length=268

 Score =  142 bits (359),  Expect = 9e-34, Method: Composition-based stats.
 Identities = 40/255 (15%), Positives = 80/255 (31%), Gaps = 28/255 (10%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  + P I A D          H ++ AGAD + + V    F   +  G  I  S  R++
Sbjct  16   RKALIPFITAGDPSLEAAVPVMHALVRAGADVIELGV---PFSDPMADGPVIQHSSERAL  72

Query  61   PRPGDAS------NTEKKPTAFFDCHMM-------VENPEKWVDDFAKCGADQFTFHYEA  107
             R    +      +  ++  A     +M       +    ++       G D        
Sbjct  73   QRGVGLAYVLQTVDVFRQSDAVTPVVLMGYLNPLEIYGIARFTQQALASGVDGVLLVDLP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMED--  165
             ++   +  +  + G+       P TS   L  L+      L      G  G   ++   
Sbjct  133  PEEADEIRAIFSAAGLALIVLASPTTSASRLATLSGVAQGYLYYVSFAGVTGADRLDAQS  192

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF----TAADPHDVIS  221
               ++  LRA+   + + V  G+            A+ +V G+++      A D      
Sbjct  193  AGDRLRGLRAQT-QVPVVVGFGIRDAASAVVMAVDADGVVVGSALVTALSDAPDVDTACR  251

Query  222  ---FMKEEVSKELRS  233
                    + + L +
Sbjct  252  RADAFLAPLRQALDA  266


>gi|7676173|sp|Q60180|TRPA_METJA  Tryptophan synthase alpha chain
Length=281

 Score =  142 bits (358),  Expect = 1e-33, Method: Composition-based stats.
 Identities = 31/226 (13%), Positives = 73/226 (32%), Gaps = 21/226 (9%)

Query  3    KPIIAPSILASDF-ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVP  61
            K  +A  +   D    +  +  +VI   AD + I +    F   +  G  I  +  R++ 
Sbjct  18   KAFVAFYV-GGDPNLEISEKALEVICKHADIVEIGI---PFSDPVADGITIQKADVRALN  73

Query  62   ------RPGDASNTEKKPTAFFD-CHMMVENP------EKWVDDFAKCGADQFTFHYEAT  108
                  +  + +    +         +   N       E++V    + G           
Sbjct  74   SGMNPLKAFELAKKLNEKAPNVPKVFLTYYNIIFKMGEEEFVKKCKEAGVSGIIVPDLPI  133

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF--MEDM  166
            ++   L    K  G+     + P T  + L ++       + +    G  G +    E+ 
Sbjct  134  EEADSLYNYCKKYGVDLIFLVAPTTPDERLKKILEKCSGFVYVVSVTGITGAREKVAEET  193

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
               ++ ++  F  +   V  G+ K    +     A+  + G+++  
Sbjct  194  KELIKRVKK-FSKIPACVGFGISKREHVEEITEIADGAIVGSAIVK  238


>gi|73622002|sp|Q89WE4|TRPA_BRAJA  Tryptophan synthase alpha chain
Length=278

 Score =  142 bits (358),  Expect = 1e-33, Method: Composition-based stats.
 Identities = 35/224 (15%), Positives = 67/224 (29%), Gaps = 19/224 (8%)

Query  6    IAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
                ++A D   A        +  +GAD + I +    F   +  G  I  +  R++   
Sbjct  20   FVTFLMAGDPDPATSLEIIKALPKSGADVIEIGM---PFTDPMADGPSIQAAGLRALKAG  76

Query  64   GDASNTEKKPTAF------FDCHMM-------VENPEKWVDDFAKCGADQFTFHYEATQD  110
                 T +    F          +M       +   +K++ D    G D         ++
Sbjct  77   MTLKKTLELVRGFRKDDNATPIVLMGYYNPIYIYGVDKFLVDAKSAGVDGLIIVDLPPEE  136

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFEL-APHLDMALVMTVEPGFGGQKFMEDMMPK  169
               L       G+       P T    L  + A        +++    G        + +
Sbjct  137  DDELCLPAMKAGLNFIRLATPTTDDKRLPAVLANTSGFVYYVSITGITGAAAADSSAVSE  196

Query  170  VETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA  213
                  +   L + V  G+      +A  + AN  V GT++  A
Sbjct  197  AVARIKRHTKLPVCVGFGIRTPETARAIASHANGAVVGTALVDA  240


>gi|20140823|sp|Q9JVE0|TRPA_NEIMA  Tryptophan synthase alpha chain
Length=261

 Score =  141 bits (357),  Expect = 2e-33, Method: Composition-based stats.
 Identities = 40/251 (15%), Positives = 79/251 (31%), Gaps = 26/251 (10%)

Query  4    PIIAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVP  61
              + P I   D          H ++  GAD L + V    F   +  G  I  +  R++ 
Sbjct  15   KALIPYITVGDPDIRTTLALMHGMVANGADILELGV---PFSDPMADGPVIQRAAERALA  71

Query  62   RPGDASNTEKKPT------AFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEAT  108
                  +                  +M            ++  + AK G D         
Sbjct  72   NGISLRDVLDVVRKFRETDTQTPVVLMGYLNPVHKMGYREFAQEAAKAGVDGVLTVDSPV  131

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--EDM  166
            +    L + +K  G+     I P T+ D +  +A      +      G  G   +  +++
Sbjct  132  ETIDPLYRELKDNGVDCIFLIAPTTTEDRIKTIAELAGGFVYYVSLKGVTGAASLDTDEV  191

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT-----AADPHDVIS  221
              K+E L      + I V  G+      +     A  ++ G+ +       A +   V+ 
Sbjct  192  SRKIEYLHQYI-DIPIGVGFGISNAESARKIGRVAEAVIVGSRIVKEIENNAGNEAAVVG  250

Query  222  FMKEEVSKELR  232
             + +E+   +R
Sbjct  251  ALVKELKDAVR  261


>gi|73622016|sp|Q6D4T9|TRPA_ERWCT  Tryptophan synthase alpha chain
Length=268

 Score =  141 bits (356),  Expect = 2e-33, Method: Composition-based stats.
 Identities = 33/231 (14%), Positives = 66/231 (28%), Gaps = 20/231 (8%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D            +I AGAD L + V    F   +  G  I  +  R+
Sbjct  15   KEGAFVPFVTLGDPSPEQSLKIIDTLIAAGADALELGV---PFSDPLADGPTIQDANLRA  71

Query  60   VPRP------GDASNTEKKPTAFFDC-HMMVEN------PEKWVDDFAKCGADQFTFHYE  106
                       +     ++         +M  N       +++    A+ G D       
Sbjct  72   FAAGVTSGQCFEMLAAIRQKYPEIPIGLLMYANLVFSNGIDEFYQRCAEVGVDSVLVADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFME  164
               +           GI       P    ++L E+A +      +    G  G   +   
Sbjct  132  PVVESAAFRAAALRHGIAPIFICPPNADDELLREIASYGRGYTYLVSRAGVTGAEKRAQL  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAAD  215
             +   V  L        +Q  G      + +   +GA   ++G+++    +
Sbjct  192  PLNHLVAKLNEYHAAPPLQGFGISDPAQVRETVASGAAGAISGSAIVRIIE  242


>gi|20140828|sp|Q9K0D4|TRPA_NEIMB  Tryptophan synthase alpha chain
Length=261

 Score =  141 bits (355),  Expect = 3e-33, Method: Composition-based stats.
 Identities = 40/252 (15%), Positives = 80/252 (31%), Gaps = 27/252 (10%)

Query  3    KPIIAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K +IA  I   D          H ++  GAD L + V    F   +  G  I  +  R++
Sbjct  15   KALIA-YITVGDPDIRTTLALMHGMVANGADILELGV---PFSDPMADGPVIQRAAERAL  70

Query  61   PRPGDASNTEKKPT------AFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEA  107
                   +                  +M            ++  + AK G D        
Sbjct  71   ANGISLRDVLDVVRKFRETDTQTPVVLMGYLNPVHKMGYREFAQEAAKAGVDGVLTVDSP  130

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--ED  165
             +    L + +K  G+     I P T+ D +  +A      +      G  G   +  ++
Sbjct  131  VETIDPLYRELKDNGVDCIFLIAPTTTEDRIKTIAELAGGFVYYVSLKGVTGAASLDTDE  190

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT-----AADPHDVI  220
            +  K+E L      + I V  G+      +     A+ ++ G+ +         +    +
Sbjct  191  VSRKIEYLHQYI-DIPIGVGFGISNAESARKIGRVADAVIVGSRIVKEIENNTGNEAAAV  249

Query  221  SFMKEEVSKELR  232
              + +E+   +R
Sbjct  250  GALVKELKDAVR  261


>gi|73622053|sp|Q67PJ3|TRPA_SYMTH  Tryptophan synthase alpha chain
Length=279

 Score =  140 bits (354),  Expect = 3e-33, Method: Composition-based stats.
 Identities = 32/253 (12%), Positives = 74/253 (29%), Gaps = 27/253 (10%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K +IA  + A D   A      H +  AG D + + +    F   +  G  I  + +R++
Sbjct  17   KGLIA-YLAAGDPSLATTRRLVHALAEAGVDMVELGL---PFSDPLADGPVIQAASQRAL  72

Query  61   PRPG------DASNTEKKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEA  107
                      +     +         +M           E +    A  G D        
Sbjct  73   AAGANTDNVLELVAALRADGLQIPLLIMTYYNLVLRPGVENFCHRAAAAGVDGLILPDVP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF-MEDM  166
             ++   +     + G+     + P +  + +   A      +      G  G +  +   
Sbjct  133  VEESDEIRAAAGAVGLDLIQFVAPTSPPERIRRAAELARGFIYAVSSTGVTGVRDRLPPQ  192

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA-------ADPHDV  219
            +  +           + V  G+ +    +   A A+  + G++            +  + 
Sbjct  193  LTAMVEAVKAVTDTPVAVGFGISRPEQVRQVTAVADAAIVGSAFVRHCGEGLPEHELVER  252

Query  220  ISFMKEEVSKELR  232
            +  + EE+    R
Sbjct  253  VRILAEELKAGTR  265


>gi|56749741|sp|Q6GH32|TRPA_STAAR  Tryptophan synthase alpha chain
Length=242

 Score =  140 bits (354),  Expect = 3e-33, Method: Composition-based stats.
 Identities = 35/249 (14%), Positives = 83/249 (33%), Gaps = 23/249 (9%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M K  I P I+ +   +L      +   GAD + I V    F   +  G  I+ + ++++
Sbjct  1    MTKLFI-PYIMGNK--DLIENATLLSENGADIIEIGV---PFSDPVADGPVIMEAGQQAI  54

Query  61   PRPGDASNTEKKPTA---FFD---CHMMVENP------EKWVDDFAKCGADQFTFHYEAT  108
             +        ++              M   N       + + +     G           
Sbjct  55   KQGITIDYIFEQLEKHGNQIKCQYVLMTYYNIICHYGEQAFFEKCRDTGVYGLIIPDLPF  114

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFMEDM  166
            +    L +     G+K    +   T    + ++  + +  +         GQ   F  ++
Sbjct  115  ELSQRLKQQFSHYGVKIISLVAMTTDDKRIKDIVSYAEGFIYTVTMNATTGQNGAFHPEL  174

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT--AADPHDVISFMK  224
              K+E+++A   ++ +    G+         K  A+ IV G+ +     ++  + I    
Sbjct  175  KRKIESIKA-IANVPVVAGFGIRSPQHVADIKEVADGIVIGSEIVKRFKSNTREEIIKYL  233

Query  225  EEVSKELRS  233
            + + + L +
Sbjct  234  QSIQQTLNN  242


>gi|7674390|sp|Q9X4E8|TRPA_RHOS4  Tryptophan synthase alpha chain
Length=263

 Score =  140 bits (354),  Expect = 4e-33, Method: Composition-based stats.
 Identities = 39/242 (16%), Positives = 77/242 (31%), Gaps = 20/242 (8%)

Query  2    VKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             K  +A  I+A D            +  AG D + + +    F   +  G  I T+ +R+
Sbjct  16   KKAFVA-YIMAGDPDLETSLAVMRGLPEAGVDIIELGM---PFTDPMADGPTIQTAGQRA  71

Query  60   VPRPGDASNTEKKPTAF------FDCHMM-VENP------EKWVDDFAKCGADQFTFHYE  106
            +      + T +   AF          MM   NP      E ++ +  + G D       
Sbjct  72   LEGGQTLTRTLEMVRAFRAENAETPIVMMGYYNPIYARGVETFLAEATEAGIDGLIVVDL  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDM  166
              ++   L    ++ G+       P T    L ++  +    +      G  G    +  
Sbjct  132  PPEEDAELCLPAQAAGLNFIRLATPTTDSRRLPKVLQNTSGFVYYVSITGITGAAAAQAA  191

Query  167  MPKVETLR-AKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKE  225
                E  R      L + V  G+      +     A+  V G+++         ++ + +
Sbjct  192  DVAPEVARIKAATDLPVIVGFGITTPEAAQDLAGIADGCVVGSAIVKLVGEGRPVAEVLD  251

Query  226  EV  227
             V
Sbjct  252  RV  253


>gi|73622055|sp|Q7TTU8|TRPA_SYNPX  Tryptophan synthase alpha chain
Length=269

 Score =  140 bits (354),  Expect = 4e-33, Method: Composition-based stats.
 Identities = 34/253 (13%), Positives = 79/253 (31%), Gaps = 25/253 (9%)

Query  2    VKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +  + P ++A D   A        + N+GAD + + +    +   +  G  I  +  R+
Sbjct  20   KRLALMPFLMAGDPDLATTSEVLLSLQNSGADMVELGM---PYSDPLADGPVIQAAAARA  76

Query  60   VPRPGDASNTEKKPTAF-----FDCHM-MVENP------EKWVDDFAKCGADQFTFHYEA  107
            +          +  T+          +    NP      E + +  A  GA         
Sbjct  77   LAAGTTPGKVLEMLTSLKGQLTIPVILFTYSNPLLNVGMEAFCERAAAAGAAGLVVPDLP  136

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF-MEDM  166
             ++   L  L + +G+     + P T  D +  +         +    G  G++  ME  
Sbjct  137  LEEAERLSPLAEQQGLDLVLLVAPTTPADRMVRIGQRSRGFTYLVSVTGVTGERAQMETR  196

Query  167  MPKVETLRAKFPHLNIQVDGGLGKE-TIPKAAKAGANVIVAGTSVF------TAADPHDV  219
            +  +     +   + + V  G+     + +    GA+  + G+++             + 
Sbjct  197  VEGLVEELKQSSAVPVAVGFGISGADQVRQVRSWGADGAIVGSALVKRMAAAGEGQIAEE  256

Query  220  ISFMKEEVSKELR  232
                  E+     
Sbjct  257  AGQFCRELRNAAD  269


>gi|73622041|sp|Q8XXY2|TRPA_RALSO  Tryptophan synthase alpha chain
Length=265

 Score =  140 bits (354),  Expect = 4e-33, Method: Composition-based stats.
 Identities = 34/254 (13%), Positives = 81/254 (31%), Gaps = 27/254 (10%)

Query  3    KPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  + P I A D          H ++  GA+ + + V    F   +  G  I  +  R++
Sbjct  16   RKGLIPFITAGDPYPELTVDLMHALVKGGANVIELGV---PFSDPMADGPVIQRASERAL  72

Query  61   PRPGDASNTEKKPTAF------FDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEA  107
             +            AF          +M           + +    ++ G D        
Sbjct  73   AKKIGLRTVLDYVRAFRATDKTTPVVLMGYANPIERMGIDAFAKAASEAGVDGVLVVDYP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF--MED  165
             ++     K +++ GI     + P ++   + ++A      +      G  G     ++ 
Sbjct  133  PEECEAFAKTMRAAGIDPIFLLAPTSTEARMAQIARVASGYIYYVSLKGVTGAATLDLDS  192

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT---AADPHDVIS-  221
            +  ++  +R     L + V  G+      +A    A+ +V G+ +      A     +  
Sbjct  193  VAARIPQIRQH-ARLPVGVGFGIRDAATARAIGGVADAVVIGSRIVQLLEEASREQAVQC  251

Query  222  --FMKEEVSKELRS  233
                  ++ + L +
Sbjct  252  LTDFIADIRQALDA  265


>gi|73622059|sp|Q5GXR6|TRPA_XANOR  Tryptophan synthase alpha chain
Length=268

 Score =  140 bits (353),  Expect = 5e-33, Method: Composition-based stats.
 Identities = 39/255 (15%), Positives = 71/255 (27%), Gaps = 29/255 (11%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  + P I A D          H ++ AGAD + + V    F   +  G  I  S  R++
Sbjct  16   RKALIPFITAGDPSLEATVPVMHALVRAGADVIELGV---PFSDPMADGPTIQRSSERAL  72

Query  61   PRPGDASNTEKKPTAF------FDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEA  107
             R    +   +    F          +M            ++ +     G D        
Sbjct  73   GRGAGLAYVLEAVHEFRREDAATPVVLMGYLNPIEIHGTRRFAEAAVAAGVDGLLLVDLP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM---E  164
             ++      +    G+       P TS   L  L       L      G  G   +    
Sbjct  133  PEEADETRAIFTEVGLALIALASPTTSEQRLDMLCSTAQGYLYYVSFAGVTGASNLLDTH  192

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF----TAADPHDV-  219
                ++  LR +     +    G+       A    A+ +V G+++      A D     
Sbjct  193  AASDRLRQLRQRAGA-PVVAGFGIKDAASAAAMAVDADGVVVGSALVAALAEADDVRSAR  251

Query  220  --ISFMKEEVSKELR  232
                     + + L 
Sbjct  252  ERAEAFLAPLRQALD  266


>gi|7674377|sp|O68429|TRPA_BUCDN  Tryptophan synthase alpha chain
Length=270

 Score =  139 bits (351),  Expect = 7e-33, Method: Composition-based stats.
 Identities = 27/231 (11%), Positives = 73/231 (31%), Gaps = 20/231 (8%)

Query  2    VKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P ++  D          + +I  GAD L + +    F   +  G+ I  +  R+
Sbjct  15   KEGCFVPFVVLGDPSLDTSLKIINILIQNGADALELGI---PFSDPLADGKTIQKANLRA  71

Query  60   VPRPGDASNTEKKPT------AFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYE  106
            + +  +     K+              +++          + +     K G D       
Sbjct  72   LSQKNNIFQYFKEIKNLRKKHTQIPIGLLIYANLVYNQGLDNFYLKCRKSGVDSVLIADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFME--  164
              ++            I +     P    D+L+ ++ +    + +   PG  G +     
Sbjct  132  PIEESEIFYTTANKYKISSIFICPPNADDDLLYRISLYAKGYIYVLSRPGVTGIENQNFF  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAAD  215
                 ++ ++       +Q  G      + +A  +G + ++ G+++    +
Sbjct  192  VSGDFIKKIKKYNSVPLLQGFGISNSIQVKQAISSGLSGVICGSAIINIIE  242


>gi|32172413|sp|O22018|TRPA_CYAME  Tryptophan synthase alpha chain
Length=243

 Score =  139 bits (351),  Expect = 8e-33, Method: Composition-based stats.
 Identities = 35/223 (15%), Positives = 70/223 (31%), Gaps = 18/223 (8%)

Query  5    IIAPSILAS--DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPR  62
            ++   + A   D         K+   GAD + I V    +   +  G  +  + ++++  
Sbjct  1    MLIAYLTAGAPDINTTKEAVMKLAKKGADVIEIGV---PYSDALADGAILQKASKQALMN  57

Query  63   PGDASNT-----EKKPTAFFDCHMMVEN------PEKWVDDFAKCGADQFTFHYEATQDP  111
                 +      E          +   N       EKWV                  ++ 
Sbjct  58   GFHLDHLWNLLSEVNEIEVPLVILAYYNQIWHYGVEKWVKKLVAHNVKGLIVPDLPYEES  117

Query  112  LHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDMMPKV  170
              L ++    G+     I P T+     ELA    D   V++     G +   +  +PK+
Sbjct  118  KTLRQICDRYGLNIIWLISPTTNKTRAQELARACKDWIYVISRTGVTGLETEFDKQIPKL  177

Query  171  ETLRAKFPHLNIQVDGGL-GKETIPKAAKAGANVIVAGTSVFT  212
                 K     I +  G+   E +      GA+ ++ G++   
Sbjct  178  IGELKKVTKAPIALGFGISKSEQVKLVKSWGADGVIIGSACMQ  220


>gi|3334388|sp|O28673|TRPA_ARCFU  Tryptophan synthase alpha chain
Length=248

 Score =  139 bits (351),  Expect = 9e-33, Method: Composition-based stats.
 Identities = 33/233 (14%), Positives = 70/233 (30%), Gaps = 20/233 (8%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPR-----PGDASNTE  70
                        +GAD + + V    F   +  G+ I  S  R++         + +   
Sbjct  18   EKTVEFMLTAAESGADVIELGV---PFSDPVADGKTIQESYVRALRNFRVERVFEIAKAF  74

Query  71   KKPTAFFDCHMMVENP------EKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIK  124
            +  +      M   NP      E +V+     G D          +    V++    G+K
Sbjct  75   RAESDKPLVLMSYYNPIYRRGVESFVEKAYSSGIDAMLVVDLPYDEAGDFVEVCSRTGMK  134

Query  125  AACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM-EDMMPKVETLRAKFPHLNIQ  183
                  P T  D L  +        +++     G +  +       ++  +         
Sbjct  135  NVFLAAPNTPEDRLRAMDELSAFVYLVSTYGVTGERDRISPLAFEALKRAKGICRKPVAV  194

Query  184  VDGGLGKETIPKAAKAGANVIVAGTSVFTAADPH-----DVISFMKEEVSKEL  231
              G    + + +   AGA+ +V G++     +       + I  + E +   L
Sbjct  195  GFGVSKADHVRQLISAGADGVVVGSAFVRLINEKGERATEDIRALTENLRSGL  247


>gi|13431943|sp|P57854|TRPA_PASMU  Tryptophan synthase alpha chain
Length=268

 Score =  138 bits (348),  Expect = 2e-32, Method: Composition-based stats.
 Identities = 31/232 (13%), Positives = 67/232 (28%), Gaps = 21/232 (9%)

Query  2    VKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D   A        ++  GAD L +      F   +  G  I  + +R+
Sbjct  15   QQGAFVPFVTLCDPNLAQSFEIIQTLVENGADALELGF---PFSDPMLDGPVIQAANQRA  71

Query  60   VPRP------GDASNTEKKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYE  106
            +                +         +++          E++    A+ G D       
Sbjct  72   LVAGCSTDASFQLLTQVRSTYPTLPISLLLCANLVYAQGIERFYQRCAEVGVDAVLIADL  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG---GQKFM  163
                      + +   I+      P    D +  +A        +    G      Q+  
Sbjct  132  PLFAHREFTVMAEKYSIQQVFICPPNACEDTIKRVAQQTQGYTYLVSRSGVTGVENQQSA  191

Query  164  EDMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAAD  215
            +++   VE L+A      +Q  G    + +    K G N  ++G++     +
Sbjct  192  DNLKTLVERLKAYQAPPILQGFGISQPQQVSDVLKIGVNGAISGSATVQIIE  243


>gi|6226268|sp|O67502|TRPA_AQUAE  Tryptophan synthase alpha chain
Length=262

 Score =  138 bits (348),  Expect = 2e-32, Method: Composition-based stats.
 Identities = 37/250 (14%), Positives = 77/250 (30%), Gaps = 28/250 (11%)

Query  4    PIIAPSILAS--DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVP  61
              +   ++    D+        +V+  G D L I      F   +  G  I  +   ++ 
Sbjct  17   KALVSYLMVGYPDYETSLKAFKEVLKNGTDILEIGF---PFSDPVADGPTIQVAHEVALK  73

Query  62   RPGDASNTEKKPTA------FFDCHMM-VENP------EKWVDDFAKCGADQFTFHYEAT  108
                  +  +               +M   NP      EK+     + G D F       
Sbjct  74   NGIRFEDVLELSETLRKEFPDIPFLLMTYYNPIFRIGLEKFCRLSREKGIDGFIVPDLPP  133

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM---ED  165
            ++   L  ++K   +       P ++   +  +    D         G  G +     E 
Sbjct  134  EEAEELKAVMKKYVLSFVPLGAPTSTRKRIKLICEAADEMTYFVSVTGTTGAREKLPYER  193

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF------TAADPHDV  219
            +  KVE  R       +   G   KE   +   + A+ +V G+++          D  ++
Sbjct  194  IKKKVEEYRELCDKPVVVGFGVSKKEHARE-IGSFADGVVVGSALVKLAGQKKIEDLGNL  252

Query  220  ISFMKEEVSK  229
            +  +KE + +
Sbjct  253  VKELKEGLRE  262


>gi|73622032|sp|Q5F9Y6|TRPA_NEIG1  Tryptophan synthase alpha chain
Length=261

 Score =  137 bits (346),  Expect = 3e-32, Method: Composition-based stats.
 Identities = 42/251 (16%), Positives = 81/251 (32%), Gaps = 26/251 (10%)

Query  4    PIIAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVP  61
              + P I   D          H ++ +GAD L + V    F   +  G  I  +  R++ 
Sbjct  15   KALIPYIAVGDPDIRTTLALMHGMVASGADILELGV---PFSDPMADGPVIQRAAERALA  71

Query  62   RPGDASNTEKKPT------AFFDCHMM-VENPE------KWVDDFAKCGADQFTFHYEAT  108
                  +                  +M   NP       ++  + AK G D         
Sbjct  72   NGISLRDVLDVVRKFRETDTQTPVVLMGYLNPIHKMGYREFAQEAAKAGVDGVLTVDSPI  131

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--EDM  166
            +    L + +K   +     I P T+ D +  +A      +      G  G   +  +++
Sbjct  132  ETIDSLYRELKDNEVDCIFLIAPTTTEDRIKTIAELAGGFVYYVSLKGVTGAASLDTDEV  191

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT-----AADPHDVIS  221
              K+E LR     + I V  G+      +     A  I+ G+ +       A +    + 
Sbjct  192  SRKIEYLRQYI-DIPIGVGFGISNAESARKIGRVAAAIIVGSRIVKEIENNAGNEAAAVG  250

Query  222  FMKEEVSKELR  232
             + +E+   +R
Sbjct  251  ALVKELKDAVR  261


>gi|732069|sp|P39362|SGCE_ECOLI  Protein sgcE
Length=210

 Score =  137 bits (346),  Expect = 3e-32, Method: Composition-based stats.
 Identities = 61/219 (27%), Positives = 98/219 (44%), Gaps = 13/219 (5%)

Query  5    IIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPG  64
            I+ PS+ +++  + G E   + N     LH+D+ D  F+ NIT G   V ++ R  P P 
Sbjct  2    ILHPSLASANPLHYGRELTALDNLDFGSLHLDIEDSSFINNITFGMKTVQAVARQTPHP-  60

Query  65   DASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIK  124
                           H M+  P++W +  A+        H E    P   +  I+  G +
Sbjct  61   ------------LSFHFMLARPQRWFNALAEIRPAWIFVHAETLDYPSETLTEIRHTGAR  108

Query  125  AACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQV  184
            A     P T +D    LA  LD  +VMT EP   GQ+F+  M  K++ +R  FP      
Sbjct  109  AGLVFNPATPIDAWRYLASELDGVMVMTSEPDGQGQRFIPSMCEKIQKVRTAFPQTECWA  168

Query  185  DGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFM  223
            DGG+      + A AGA  +V G ++F+++D    ++  
Sbjct  169  DGGITLAAAQQLAAAGAQHMVIGRALFSSSDYRATLAQF  207


>gi|73622009|sp|Q7NUD9|TRPA_CHRVO  Tryptophan synthase alpha chain
Length=262

 Score =  136 bits (344),  Expect = 5e-32, Method: Composition-based stats.
 Identities = 46/250 (18%), Positives = 84/250 (33%), Gaps = 23/250 (9%)

Query  3    KPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K  + P I A D          H +++ GAD + + V    F   +  G  I  +  R++
Sbjct  14   KKALIPFITAGDPHPGLTVSLMHGLVDGGADIIELGV---PFSDPMADGPVIQRASERAL  70

Query  61   PRPGDASNTEKKPTAF------FDCHMM-VENPE------KWVDDFAKCGADQFTFHYEA  107
                   +  +    F          +M   NP       ++       G D        
Sbjct  71   KHKVGLRHVLEMVAEFRRDNATTPVVLMGYLNPLCAMGYTEFASRAKAAGVDGVLTVDCP  130

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF--MED  165
             ++   L   + + G+     + P T    + E+A      +      G  G     +ED
Sbjct  131  PEEAAELESALDAHGLDTVFLVAPTTPPSRVAEIAKLARGYVYYVSLKGVTGAGHLDIED  190

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPH--DVISFM  223
            +  K+  LR + P L I V  G+      KA  A A+ +V G+ +    +    +     
Sbjct  191  VARKIAALRQQLP-LPIGVGFGIRDAATAKAIAAAADAVVVGSRLVQEIEAATPETAREQ  249

Query  224  KEEVSKELRS  233
               +  EL++
Sbjct  250  LTRLVAELKA  259


>gi|73622043|sp|Q6NDN5|TRPA_RHOPA  Tryptophan synthase alpha chain
Length=278

 Score =  134 bits (339),  Expect = 2e-31, Method: Composition-based stats.
 Identities = 38/247 (15%), Positives = 74/247 (29%), Gaps = 28/247 (11%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +P +   ++A D            +  AGAD + I +    F   +  G  I  +  R++
Sbjct  17   RPALVTFVMAGDPDLDTSLQILKVLPAAGADVIEIGM---PFTDPMADGPAIQAAGLRAL  73

Query  61   PRPGDASNTEKKPTAF------FDCHMM-------VENPEKWVDDFAKCGADQFTFHYEA  107
                    T      F          +M       +   + ++ D    G D        
Sbjct  74   KAGTTLKKTLGLVRDFRATDNATPLVLMGYYNPIYIYGVDAFLADAKAAGVDGLIIVDLP  133

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFEL-APHLDMALVMTVEPGFGGQKFMEDM  166
             ++   L       G+       P T    L  + A        +++    G        
Sbjct  134  PEEDEELCLPAMKAGLNFIRLATPTTDEKRLPAVLANTSGFVYYVSITGITGSASADASA  193

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
            +        +  +L + V  G+      +A  A AN  V G+++  A         +K  
Sbjct  194  VGAAVQRIKRHTNLPVCVGFGIRTPDAAQAIAAQANGAVVGSALIDA---------LKAS  244

Query  227  VSKELRS  233
            ++ E R+
Sbjct  245  LNAEGRA  251


>gi|73621986|sp|Q6FEE6|TRPA_ACIAD  Tryptophan synthase alpha chain
Length=267

 Score =  134 bits (339),  Expect = 2e-31, Method: Composition-based stats.
 Identities = 31/248 (12%), Positives = 77/248 (31%), Gaps = 24/248 (9%)

Query  2    VKPIIAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +  +   ++A D          HK++ AG D + + +    F   +  G  I  +  R+
Sbjct  15   QRKALVSYVMAGDPQPQVSVPLLHKMVEAGVDVIELGL---PFSDPMADGPVIALAAERA  71

Query  60   VPRPGDASNTEKKPTAF------FDCHMMVE-------NPEKWVDDFAKCGADQFTFHYE  106
            +    +  +       F          +M           EK+V     CG D       
Sbjct  72   LAAGTNTLDALNMVKEFRQNDSETPVVLMGYLNPVEVIGYEKFVSHAKACGVDGVLLVDL  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFME--  164
              ++      ++K   +     + P ++   +  +       +      G  G   ++  
Sbjct  132  PPEEAKEFDVVLKQHDMDQIFLLAPTSTDQRIEHVVKQASGFIYYVSLKGVTGAATLDVT  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT---AADPHDVIS  221
            +   ++  ++ K   + + V  G+      KA    A+ ++ G++             + 
Sbjct  192  EAAERIAKIKTKT-SVPVGVGFGISDAASAKAMGQVADAVIVGSAFVKPFATLAIDQAVE  250

Query  222  FMKEEVSK  229
                +V +
Sbjct  251  QTVNKVKE  258


>gi|68053105|sp|Q6B8L2|TRPA_GRATL  Tryptophan synthase alpha chain
Length=268

 Score =  134 bits (338),  Expect = 2e-31, Method: Composition-based stats.
 Identities = 28/222 (12%), Positives = 73/222 (32%), Gaps = 19/222 (8%)

Query  6    IAPSILAS--DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            + P I A   +          +   GAD + + +    +   +  G  I  + + ++ + 
Sbjct  17   LIPFITAGYPNIDICIKALKVLDREGADLIELGI---PYSDALADGPIIQEASQAALKQG  73

Query  64   GDASNTEKKPTAFFD------CHMMVENP------EKWVDDFAKCGADQFTFHYEATQDP  111
                      T                NP      +K++ + ++ GA          ++ 
Sbjct  74   IYIEQVLSILTKVIPDLHAPIIIFTYYNPVLVRGVDKFICEISQAGAKGLIIPDLPLEEV  133

Query  112  LHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDM-MPKV  170
             ++++L     I+    + P +S   +  +A      + +    G  G +   D+ +  +
Sbjct  134  DYILELCNLYSIELILFVAPTSSQSRIQLIASKSPGCIYLVSSCGVTGLRDNFDVKIQHL  193

Query  171  ETLRAKFPHLNIQVDGGL-GKETIPKAAKAGANVIVAGTSVF  211
                    +  I +  G+   + I +      + IV G+++ 
Sbjct  194  ANNIKSTTNKLIMLGFGINNPDQISQIINWNIDGIVVGSAII  235


>gi|73622024|sp|Q5QX79|TRPA_IDILO  Tryptophan synthase alpha chain
Length=269

 Score =  134 bits (338),  Expect = 3e-31, Method: Composition-based stats.
 Identities = 34/227 (14%), Positives = 68/227 (29%), Gaps = 20/227 (8%)

Query  2    VKPIIAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D            +I+ GAD L + +    F   +  G  I  +  R+
Sbjct  15   NQGAFVPFVTLGDPTPGQSVDVIKALIDGGADALELGL---PFSDPVADGPMIQRANLRA  71

Query  60   VPRPGDASNTEKKPTA------FFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYE  106
            +       +  +               ++V            +       G D       
Sbjct  72   LESGTTFKHILEILKEIRDYSPQIPIGLLVYANLIYAKGVRNFYQQMKDAGVDSVLIADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--FME  164
             T++      + K  GI+A     P  S  +L ++A      + +    G  G       
Sbjct  132  PTKEAKRFADIAKEIGIEAVFIAPPDASDALLIDIAKQCAGYVYLLSRSGVTGADTQMQA  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF  211
                 +  L+       +   G    E + +A  AGA+  ++G++V 
Sbjct  192  PASELINKLKEAGAPPTLLGFGISQPEHVQRALAAGADGAISGSAVV  238


>gi|59799055|sp|Q72U04|TRPA_LEPIC  Tryptophan synthase alpha chain
 gi|59799065|sp|Q8F150|TRPA_LEPIN  Tryptophan synthase alpha chain
Length=264

 Score =  134 bits (338),  Expect = 3e-31, Method: Composition-based stats.
 Identities = 33/224 (14%), Positives = 65/224 (29%), Gaps = 23/224 (10%)

Query  6    IAPSILASDFANLGCEC--HKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
              P I   D     C      +I  GA  L + +    F   +  G  I  + +RS+  P
Sbjct  15   FIPYISLGDPDYDSCVIWADALIRGGAGILELGI---PFTDPVADGPVIQKAFKRSLAHP  71

Query  64   GDASNTEK------KPTAFFDCH-MMVENP------EKWVDDFAKCGADQFTFHYEATQ-  109
                   +      K         +   NP      E + +     G             
Sbjct  72   FSMDKILEVTSEIHKLHPQIPLVYLTYFNPLFSMGLESFTERAKNSGIQGLIIPDLPFDT  131

Query  110  -DPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDMM  167
             +       ++ K I     + P T+ D +  +          +T     G +  +   +
Sbjct  132  PEAEEFFSQLERKRIDFIHLVTPATTEDRIRSMKSLASGFIYYVTSYGVTGERGSIASGL  191

Query  168  P-KVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSV  210
              ++  +R     L +    G+      K     A+ ++ G++V
Sbjct  192  EDRIRMVRKIVG-LPVCAGFGISTSDQSKVISTYADGVIIGSAV  234


>gi|136265|sp|P00929|TRPA_SALTY  Tryptophan synthase alpha chain
Length=268

 Score =  134 bits (337),  Expect = 3e-31, Method: Composition-based stats.
 Identities = 39/246 (15%), Positives = 78/246 (31%), Gaps = 25/246 (10%)

Query  6    IAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
              P +   D            +I+AGAD L + V    F   +  G  I  +  R+    
Sbjct  19   FVPFVTLGDPGIEQSLKIIDTLIDAGADALELGV---PFSDPLADGPTIQNANLRAFAAG  75

Query  64   GDASNTEKKPTAFFDCH-------MMVEN------PEKWVDDFAKCGADQFTFHYEATQD  110
               +   +      + H       +M  N       + +     + G D         ++
Sbjct  76   VTPAQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQVGVDSVLVADVPVEE  135

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMM--P  168
                 +      I       P    D+L ++A +      +    G  G +    +    
Sbjct  136  SAPFRQAALRHNIAPIFICPPNADDDLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHH  195

Query  169  KVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA-----ADPHDVISFM  223
             +E L+       +Q  G    E +  A +AGA   ++G+++        A P  +++ +
Sbjct  196  LIEKLKEYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLASPKQMLAEL  255

Query  224  KEEVSK  229
            +  VS 
Sbjct  256  RSFVSA  261


>gi|28380180|sp|Q8P7S0|TRPA_XANCP  Tryptophan synthase alpha chain
Length=272

 Score =  134 bits (337),  Expect = 3e-31, Method: Composition-based stats.
 Identities = 38/256 (14%), Positives = 73/256 (28%), Gaps = 29/256 (11%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  + P I A D          H ++ AGA+ + + V    F   +  G  I  S  R++
Sbjct  20   RKALIPFITAGDPSLEATVPVMHALVRAGANIIELGV---PFSDPMADGPTIQRSSERAL  76

Query  61   PRPGDASNTEKKPTAF------FDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEA  107
             R    +   +    F          +M            ++ +     G D        
Sbjct  77   GRGAGLAYVIEAVQEFRREDATTPVVLMGYLNPIEIHGTRRFAETAVAAGIDGVLLVDLP  136

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK---FME  164
             ++      +    G+       P T    L  L       L      G  G        
Sbjct  137  PEEADETRAIFTEVGLALIALASPTTGEARLDMLCSTAQGYLYYVSFSGVTGAADRLDTH  196

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF----TAADPHDV-  219
                ++  LRA+     +    G+       A    A+ +V G+++      A+D     
Sbjct  197  AASDRLRQLRARAGA-PVVAGFGIKDAASAAAMAVDADGVVVGSALVAALADASDVRSAR  255

Query  220  --ISFMKEEVSKELRS  233
                   + + + L +
Sbjct  256  KRAEDFLQPLRQALDA  271


>gi|1174781|sp|P42389|TRPA_BUCAP  Tryptophan synthase alpha chain
Length=271

 Score =  133 bits (336),  Expect = 4e-31, Method: Composition-based stats.
 Identities = 33/257 (12%), Positives = 82/257 (31%), Gaps = 28/257 (10%)

Query  1    MVKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRR  58
            + +    P ++  D            +I  GAD L + +    F   +  G  I  +  R
Sbjct  14   LKEGCFVPFVVIGDPSLEMSLKIIETLIENGADALELGI---PFSDPLADGPIIQKASLR  70

Query  59   SVPRPGDASNTEKKPTAFFD--CHMMV-----------ENPEKWVDDFAKCGADQFTFHY  105
            ++ +        +      +   H+ +              + +     + G D      
Sbjct  71   ALYKKNTFLQCFELIENIRNKYLHLPIGILLYANLVYNYGIKNFYYQCFRSGLDSVLIAD  130

Query  106  EATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFM  163
               ++     K+     I +     P     +L +++ +    + +   PG  G   K +
Sbjct  131  IPIEEYEPFYKIANQYNINSIFICPPDADDSLLSKISLYAKGYIYLLSRPGVTGIEKKTI  190

Query  164  EDMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADP-----HD  218
                  +E ++       +Q  G      I K+  +G N ++ G+++    +        
Sbjct  191  SLSNIFIEKIKKYNSLPLLQGFGIENPTQIQKSILSGTNGVICGSAIIDIIEKNLNKEKK  250

Query  219  VISFMKE---EVSKELR  232
            +I+ +K    ++ K  +
Sbjct  251  MINEIKNFTSKLKKATK  267


>gi|2822116|sp|P16578|TRP_COPCI  Tryptophan synthase
Length=702

 Score =  133 bits (336),  Expect = 4e-31, Method: Composition-based stats.
 Identities = 34/216 (15%), Positives = 70/216 (32%), Gaps = 21/216 (9%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKPTA  75
             +       +   GAD + + +    F   I  G  I  +   ++    D      +   
Sbjct  28   EDTVPVLLALQAGGADIIELGI---PFSDPIADGPVIQEANTVALKNDIDYPTVLGQIRE  84

Query  76   F------FDCHMM-VENP------EKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKG  122
                       +M   NP      +K + D A+ GA+ F       ++ +   +   +  
Sbjct  85   ARQQGLTAPVLLMGYYNPMLAYGEDKAIQDAAEAGANGFIMVDLPPEEAIAFRQKCAASN  144

Query  123  IKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG----GQKFMEDMMPKVETLRAKFP  178
            +     I P T++  +  LA   D  + +  + G           E++   +  +R    
Sbjct  145  LSYVPLIAPSTTLKRIQFLASIADSFIYVVSKMGTTGSSANVAVNEELPTILSRIREYTH  204

Query  179  HLNIQVDGGLGKETIPKAAKAGANVIVA-GTSVFTA  213
                   G   ++     A AGA+ +V  G+ +  A
Sbjct  205  VPLAVEFGVATRDQFNYVADAGADGVVVIGSRIVNA  240


>gi|20140618|sp|Q8Z7E0|TRPA_SALTI  Tryptophan synthase alpha chain
Length=268

 Score =  133 bits (336),  Expect = 4e-31, Method: Composition-based stats.
 Identities = 39/246 (15%), Positives = 78/246 (31%), Gaps = 25/246 (10%)

Query  6    IAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
              P +   D            +I+AGAD L + V    F   +  G  I  +  R+    
Sbjct  19   FVPFVTLGDPGIEQSLKIIDTLIDAGADALELGV---PFSDPLADGPTIQNANLRAFAAG  75

Query  64   GDASNTEKKPTAFFDCH-------MMVEN------PEKWVDDFAKCGADQFTFHYEATQD  110
               +   +      + H       +M  N       + +     + G D         ++
Sbjct  76   VTPAQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQVGVDSVLVADVPVEE  135

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMM--P  168
                 +      I       P    D+L ++A +      +    G  G +    +    
Sbjct  136  SAPFRQAALRHNIAPIFICPPNADDDLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHH  195

Query  169  KVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA-----ADPHDVISFM  223
             +E L+       +Q  G    E +  A +AGA   ++G+++        A P  +++ +
Sbjct  196  LIEKLKEYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLASPEQMLAEL  255

Query  224  KEEVSK  229
            +  VS 
Sbjct  256  RSFVSA  261


>gi|73622044|sp|Q57NT2|TRPA_SALCH  Tryptophan synthase alpha chain
Length=268

 Score =  133 bits (336),  Expect = 4e-31, Method: Composition-based stats.
 Identities = 38/246 (15%), Positives = 78/246 (31%), Gaps = 25/246 (10%)

Query  6    IAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
              P +   D            +I++GAD L + V    F   +  G  I  +  R+    
Sbjct  19   FVPFVTLGDPGIEQSLKIIDTLIDSGADALELGV---PFSDPLADGPTIQNANLRAFAAG  75

Query  64   GDASNTEKKPTAFFDCH-------MMVEN------PEKWVDDFAKCGADQFTFHYEATQD  110
               +   +      + H       +M  N       + +     + G D         ++
Sbjct  76   VTPAQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQVGVDSVLVADVPVEE  135

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMM--P  168
                 +      I       P    D+L ++A +      +    G  G +    +    
Sbjct  136  SAPFRQAALRHNIAPIFICPPNADDDLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHH  195

Query  169  KVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA-----ADPHDVISFM  223
             +E L+       +Q  G    E +  A +AGA   ++G+++        A P  +++ +
Sbjct  196  LIEKLKEYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLASPEQMLAEL  255

Query  224  KEEVSK  229
            +  VS 
Sbjct  256  RSFVSA  261


>gi|73622057|sp|Q5E624|TRPA_VIBF1  Tryptophan synthase alpha chain
Length=268

 Score =  133 bits (336),  Expect = 4e-31, Method: Composition-based stats.
 Identities = 37/235 (15%), Positives = 67/235 (28%), Gaps = 20/235 (8%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D            +I AGAD L + +    F   +  G  I  +  R+
Sbjct  15   NQGAFVPFVTIGDPNPELSYDIMETLIEAGADALELGI---PFSDPLADGPTIQGANIRA  71

Query  60   VPRPGDASNTEKKPT------AFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYE  106
            +      +   +  T            ++V          + +     + G D       
Sbjct  72   LDSKTTPAICFELITKIRSKYPDTPIGLLVYANLVFANGIDNFYTKCQQAGVDSVLIADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFME  164
             T +     +     GI       P  S + L  +A        +    G  G   K   
Sbjct  132  PTNESQEFRESAIEHGIHPIFIAPPSASPETLETVAKLGGGYTYLLSRAGVTGAETKAGM  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDV  219
             +   +E L        I   G      + +A KAGA   ++G++     + H  
Sbjct  192  PVAQLLERLNQYDAPPAILGFGISEPAQVEEAVKAGAAGAISGSATVKLIEQHQA  246


>gi|28380203|sp|Q97EF6|TRPA_CLOAB  Tryptophan synthase alpha chain
Length=263

 Score =  133 bits (336),  Expect = 5e-31, Method: Composition-based stats.
 Identities = 29/248 (11%), Positives = 79/248 (31%), Gaps = 23/248 (9%)

Query  2    VKPIIAPSILAS--DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             K  + P + +   D         ++  +GAD + + +    +   +  G  I  S   +
Sbjct  16   NKKAMIPFVTSGYPDVETTKKIVIEMEKSGADLIELGI---PYSDPVADGPIIQISSSGA  72

Query  60   VPRPGDASNTEKKPTAF-----FDCHMM-------VENPEKWVDDFAKCGADQFTFHYEA  107
            +       +                  M           EK++ D  + G D        
Sbjct  73   LNNGLKIKDIMNMVKEVRKNVKIPIVYMGYFGCVFKYGLEKFIKDSKESGVDGIVIPDLP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK-FMEDM  166
             ++   + ++           + P TS D + ++       +      G  G +  + + 
Sbjct  133  LEERERVKEIADRYEFYIIPLVAP-TSEDRIGKIVNGAKGFIYCVSTNGVTGVRNIIAND  191

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAAD----PHDVISF  222
            +     + +K  ++   +  G+    + +  K   + ++ G++V    +      ++I  
Sbjct  192  VKAYIDVVSKASNVPKCIGFGISSPEMAQKMKEYCDGVIIGSAVMKIVEEDIPKEEMIRK  251

Query  223  MKEEVSKE  230
            + E +S+ 
Sbjct  252  VGEFISQV  259


>gi|20140578|sp|Q8X7B5|TRPA_ECO57  Tryptophan synthase alpha chain
Length=268

 Score =  133 bits (335),  Expect = 5e-31, Method: Composition-based stats.
 Identities = 35/249 (14%), Positives = 75/249 (30%), Gaps = 25/249 (10%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D            +I AGAD L + +    F   +  G  I  +  R+
Sbjct  15   KEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADTLELGI---PFSDPLADGPTIQNATLRA  71

Query  60   VPRP------GDASNTEKKPTAFFDC-HMMVEN------PEKWVDDFAKCGADQFTFHYE  106
                       +     ++         +M  N       +++     K G D       
Sbjct  72   FAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDM  166
              ++     +      +       P    D+L ++A +      +    G  G +    +
Sbjct  132  PVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAAL  191

Query  167  M--PKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAA-----DPHDV  219
                 V  L+       +Q  G    + +  A  AGA   ++G+++         +P  +
Sbjct  192  PLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPKKM  251

Query  220  ISFMKEEVS  228
            ++ +K  V 
Sbjct  252  LAALKAFVQ  260


>gi|73622042|sp|Q7URN0|TRPA_RHOBA  Tryptophan synthase alpha chain
Length=278

 Score =  133 bits (335),  Expect = 6e-31, Method: Composition-based stats.
 Identities = 42/267 (15%), Positives = 79/267 (29%), Gaps = 39/267 (14%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +  + P +   D               AGAD   + V    +   I  G  I  S +R+
Sbjct  15   NRKALMPFLTTGDPNIDTTEAVIAAARQAGADLCEVGV---PYSDPIADGPVIQASYQRA  71

Query  60   VPRPGDASNT--------EKKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFH  104
            +       +         E           MV           K+VD   + G       
Sbjct  72   LDAGFKLQHVWDLGQRLTENPKVKAMPRVTMVSYSIIYRIGMAKYVDQAMQAGYCGAIVP  131

Query  105  YEATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--F  162
                ++   L K+ + KG      + P T+ D    +A      L      G  G++   
Sbjct  132  DLLVEEAEDLSKICREKGFDLIQLVTPTTTRDRQCRIAELSSGFLYYVSVTGITGERTAL  191

Query  163  MEDMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT----------  212
              +++  V  LR +         G  G ET  + A   ++ ++ G+++            
Sbjct  192  PTNLVDNVGWLREQTELPICIGFGISGPETAAQLAPV-SDGLIVGSAIVRRVADAVEKAK  250

Query  213  --AADPHDVISF----MKEEVSKELRS  233
               ADP    +         + + + +
Sbjct  251  SSGADPVKTAAEEAGDFCHSLRQAIDA  277


>gi|3915890|sp|P34793|TRP2_CYACA  Tryptophan synthase alpha chain
Length=242

 Score =  133 bits (334),  Expect = 7e-31, Method: Composition-based stats.
 Identities = 34/233 (14%), Positives = 70/233 (30%), Gaps = 21/233 (9%)

Query  12   ASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDAS---N  68
            A D          + N GAD + I V    +   +  G  +  + ++++          +
Sbjct  10   APDLNTTKQALLNLANDGADVIEIGV---PYSDPLADGMILQKASQQALKNRFRLEQLWH  66

Query  69   TEKKPTAFFDCH-MMVEN------PEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSK  121
               +         +   N       EKWV                  ++   L       
Sbjct  67   LLAEIELPVPVVILAYYNQIFHYGVEKWVTTLVNLKVKALIVPDLPYEEAAILRAACARH  126

Query  122  GIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHL  180
             +     I P T      +LA    D   +++     G     ++ +P +     +    
Sbjct  127  HLHMIWLISPTTPKVRAKQLALACDDWIYLVSRTGVTGVDAHFDNQIPNMIAELKQVTTT  186

Query  181  NIQVDGGLGKETIPKAAK-AGANVIVAGTSVFTA------ADPHDVISFMKEE  226
             I +  G+ ++   +  K  GA+ ++ GT+              + IS MK+ 
Sbjct  187  PIALGFGIHQKQQLQLVKSWGADGVIIGTACMQILLEKGVDQLTEWISAMKKS  239


>gi|136258|sp|P18284|TRPA_HALVO  Tryptophan synthase alpha chain
Length=277

 Score =  132 bits (333),  Expect = 9e-31, Method: Composition-based stats.
 Identities = 39/253 (15%), Positives = 77/253 (30%), Gaps = 27/253 (10%)

Query  4    PIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVP  61
            P   P + A D    +       +   GAD + + +    F   I  G  I  ++ RS+ 
Sbjct  11   PAFVPYLAAGDPDYESSLEYVEALERGGADVIELGL---PFSEPIAEGPTIQNAVVRSLE  67

Query  62   RPGD----ASNTEKKPTAFFDCHMMVEN----------PEKWVDDFAKCGADQFTFHYEA  107
                        E    +     M   N          P  +V+  A+ G + F      
Sbjct  68   GGMTPTRFFEFVEDLDVSVPLVCMRYYNLIYRYGDEPGPRPFVEKAAEVGIEGFVVPDLP  127

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDM  166
             ++   L +     G+     + P T  + L  +   +     V       G Q  + D 
Sbjct  128  AEEAGPLREACDEFGLDLVFIVAPTTRGERLDRIMEQVSGYVYVQARLGTTGAQSSVSDQ  187

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF-------TAADPHDV  219
                      +        G    +   +   +GA+ I+ G+++           D  + 
Sbjct  188  TDSSLERLTDYDVPKAVGFGISDGDHAERIVASGADGIIVGSALVDIVAEGHENGDDAET  247

Query  220  ISFMKEEVSKELR  232
            ++   E +++EL 
Sbjct  248  VADRLETLARELE  260


>gi|401211|sp|P31204|TRPA_ANTSP  Tryptophan synthase alpha chain
Length=263

 Score =  132 bits (333),  Expect = 9e-31, Method: Composition-based stats.
 Identities = 35/247 (14%), Positives = 76/247 (30%), Gaps = 25/247 (10%)

Query  6    IAPSILAS--DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            + P I A   D        +++ + GAD + + +    +   +  G  I  S   ++   
Sbjct  17   LIPFITAGYPDINTTIQALYELDSQGADIIELGI---PYSDALADGSVIQHSSLIALQGG  73

Query  64   GDASNTEKKPTAF------FDCHMMVENP------EKWVDDFAKCGADQFTFHYEATQDP  111
                                   +   NP      EK++   +  GA          ++ 
Sbjct  74   TYIDQVLHILEVVSTKLNTPIIILPYYNPILKRGIEKFIKQISLMGAKGLIVPDLPLEET  133

Query  112  LHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMED--MMPK  169
              L+ +     I+    + P +S+  +  ++      + +    G  G +   D  +M  
Sbjct  134  DELIVICNDNQIELVLFVAPTSSMKRINSISKKSPGCIYLVSSTGVTGVRDDIDIKVMEL  193

Query  170  VETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF------TAADPHDVISFM  223
               ++       +   G    E I K  K   + +V G++           D    IS +
Sbjct  194  SNYIKKVSNKFIMLGFGISTPEHIKKIMKWNIDGVVVGSAFVKKLSALKIDDRISSISSL  253

Query  224  KEEVSKE  230
             + + K 
Sbjct  254  CKSLKKA  260


>gi|29428206|sp|Q8FHW0|TRPA_ECOL6  Tryptophan synthase alpha chain
Length=268

 Score =  132 bits (333),  Expect = 9e-31, Method: Composition-based stats.
 Identities = 35/249 (14%), Positives = 76/249 (30%), Gaps = 25/249 (10%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D            +I AGAD L + +    F   +  G  I  +  R+
Sbjct  15   KEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGI---PFSDPLADGPTIQNATLRA  71

Query  60   VPRP------GDASNTEKKPTAFFDC-HMMVEN------PEKWVDDFAKCGADQFTFHYE  106
                       +     ++         +M  N       +++  +  K G D       
Sbjct  72   FAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAECEKVGVDSVLVADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDM  166
              ++     +      +       P    D+L ++A +      +    G  G +    +
Sbjct  132  PVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAAL  191

Query  167  M--PKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAA-----DPHDV  219
                 V  L+       +Q  G    + +  A  AGA   ++G+++         +P  +
Sbjct  192  PLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKM  251

Query  220  ISFMKEEVS  228
            ++ +K  V 
Sbjct  252  LAALKAFVQ  260


>gi|67473577|sp|P0A877|TRPA_ECOLI  Tryptophan synthase alpha chain
 gi|67473580|sp|P0A878|TRPA_SHIFL  Tryptophan synthase alpha chain
Length=268

 Score =  132 bits (332),  Expect = 1e-30, Method: Composition-based stats.
 Identities = 34/245 (13%), Positives = 74/245 (30%), Gaps = 25/245 (10%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D            +I AGAD L + +    F   +  G  I  +  R+
Sbjct  15   KEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGI---PFSDPLADGPTIQNATLRA  71

Query  60   VPRP------GDASNTEKKPTAFFDC-HMMVEN------PEKWVDDFAKCGADQFTFHYE  106
                       +     ++         +M  N       +++     K G D       
Sbjct  72   FAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDM  166
              ++     +      +       P    D+L ++A +      +    G  G +    +
Sbjct  132  PVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAAL  191

Query  167  M--PKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAA-----DPHDV  219
                 V  L+       +Q  G    + +  A  AGA   ++G+++         +P  +
Sbjct  192  PLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKM  251

Query  220  ISFMK  224
            ++ +K
Sbjct  252  LAALK  256


>gi|61217178|sp|Q5MI53|TRPA_LEPBI  Tryptophan synthase alpha chain
Length=266

 Score =  132 bits (332),  Expect = 1e-30, Method: Composition-based stats.
 Identities = 35/255 (13%), Positives = 80/255 (31%), Gaps = 34/255 (13%)

Query  3    KPIIAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K    P     D    +       +++ GAD L + +    F   +  G  I  ++ RS+
Sbjct  14   KSAFIPYFTLGDPNYNDSIEFGKTILDGGADILELGI---PFSDPVADGPVIQRAVARSL  70

Query  61   PRPGDASNTEKKPTAFFDCH--------MMVENPE------KWVDDFAKCGADQFTFHYE  106
                      +  T     H        +   NP       K++D+    G         
Sbjct  71   KNKFSFDEIFR-VTKQIHLHKQETPLVYLTYFNPIYHCGITKFLDNAKDSGVVGLVIPDL  129

Query  107  ATQ--DPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--F  162
                 +   L + ++ + +     + P ++   +  L       +      G  G++  F
Sbjct  130  PFDTIESETLFQELRLRDMDLIHLVTPASTKKRIEALRKTSTGFIYYVTSFGVTGERREF  189

Query  163  MEDMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISF  222
              D+  ++  L+     L I    G+            A+ I+ G+++            
Sbjct  190  SVDLKERIRFLKDTI-QLPICAGFGISTPEQASQIAGYADGIIIGSAI---------QRV  239

Query  223  MKEEVSKELRSRDLL  237
            ++E      +++++L
Sbjct  240  IEENGQDASKAKNVL  254


>gi|73622028|sp|Q65TE9|TRPA_MANSM  Tryptophan synthase alpha chain
Length=268

 Score =  132 bits (332),  Expect = 1e-30, Method: Composition-based stats.
 Identities = 34/255 (13%), Positives = 72/255 (28%), Gaps = 33/255 (12%)

Query  2    VKPIIAPSIL--ASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +     D          +++ GAD L +      F   +  G  I  +  R+
Sbjct  15   KQGGFVPFVTLCDPDLERSFDIICTLVDNGADALELGF---PFSDPLLDGPVIQAANNRA  71

Query  60   VPRP------GDASNTEKKPTAFFDCHMMVEN-------PEKWVDDFAKCGADQFTFHYE  106
            +                +         +++          + +    A+ G D       
Sbjct  72   LNAGCSTAESFKLLEKVRSKYPEIPIGLLLCANLIYAQTLDGFYRRCAEIGIDAVLVADI  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG---GQKFM  163
                    ++  K  GI+      P    + +  +A H +    +    G      Q   
Sbjct  132  PLLAAEPYIQAAKKHGIQPVFICPPNADENTVKGVAEHSEGYTYLVSRAGVTSAENQSHA  191

Query  164  EDMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA----------  213
             ++   VE L+A      +Q  G    + + +A   G    ++G++              
Sbjct  192  ANLDSLVEQLKAHNAPPILQGFGIAKPQQVKEALNMGVAGAISGSATVKIIEANLDNHEK  251

Query  214  --ADPHDVISFMKEE  226
              AD  + +  MK  
Sbjct  252  CLADLAEFVKNMKAA  266


>gi|73622045|sp|Q5PNM0|TRPA_SALPA  Tryptophan synthase alpha chain
Length=268

 Score =  131 bits (331),  Expect = 1e-30, Method: Composition-based stats.
 Identities = 38/246 (15%), Positives = 78/246 (31%), Gaps = 25/246 (10%)

Query  6    IAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
              P +   D            +I+AGA+ L + V    F   +  G  I  +  R+    
Sbjct  19   FVPFVTLGDPGIEQSLKIIDTLIDAGANALELGV---PFSDPLADGPTIQNANLRAFAAG  75

Query  64   GDASNTEKKPTAFFDCH-------MMVEN------PEKWVDDFAKCGADQFTFHYEATQD  110
               +   +      + H       +M  N       + +     + G D         ++
Sbjct  76   VTPAQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQVGVDSVLVADVPVEE  135

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMM--P  168
                 +      I       P    D+L ++A +      +    G  G +    +    
Sbjct  136  SAPFRQAALRHNIAPIFICPPNADDDLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHH  195

Query  169  KVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA-----ADPHDVISFM  223
             +E L+       +Q  G    E +  A +AGA   ++G+++        A P  +++ +
Sbjct  196  LIEKLKEYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLASPEQMLAEL  255

Query  224  KEEVSK  229
            +  VS 
Sbjct  256  RSFVSA  261


>gi|136260|sp|P17166|TRPA_LACCA  Tryptophan synthase alpha chain
Length=266

 Score =  131 bits (331),  Expect = 2e-30, Method: Composition-based stats.
 Identities = 33/252 (13%), Positives = 78/252 (30%), Gaps = 26/252 (10%)

Query  4    PIIAPSILA--SDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS--  59
             +  P I+A   DF         +   GAD + + +    F   +  G  I  +  R+  
Sbjct  14   KVFIPFIVADDPDFETTVKNVVALAKGGADIVELGI---PFSDPVADGPVIQAADLRAFA  70

Query  60   ----VPRPGDASNTEKKPTAFFDCHMMV------ENPEKWVDDFAKCGADQFTFHYEATQ  109
                     D     +K TA     +           + ++   A              +
Sbjct  71   ANVRTKTVFDIVEAARKETAVPIVFLTYLNIVFKYGYDAFLKRCADLNVAGLVIPDLPYE  130

Query  110  DPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--FMEDMM  167
                +V + +  GI     I P TS   + ++A      + +    G  G++  F   + 
Sbjct  131  SRDEIVPIAEKYGIDIIPLITP-TSGHRIEKIAKSASGFIYVVSSMGITGERDEFFAGLK  189

Query  168  PKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF-----TAADPHDVISF  222
              V  ++    ++   +  G+      +     A+ ++ G+++              I  
Sbjct  190  ALVAEIKQYT-NVPTAIGFGIHTPEQAQTMAGIADGVIIGSAIVDLVAKEKQQAPAAIEK  248

Query  223  MKEEVSKELRSR  234
              +++   + ++
Sbjct  249  FTKQIRVAVDAK  260


>gi|136259|sp|P00930|TRPA_KLEAE  Tryptophan synthase alpha chain
Length=269

 Score =  131 bits (330),  Expect = 2e-30, Method: Composition-based stats.
 Identities = 39/249 (15%), Positives = 74/249 (29%), Gaps = 25/249 (10%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D            +I  GAD L + +    F   +  G  I  +  R+
Sbjct  15   QEGAFVPFVTLGDPGPEQSLKIIDALIEGGADALELGI---PFSDPLADGPTIQGAALRA  71

Query  60   VPRPGDASNTEKKPTAFFDCH-------MMVEN------PEKWVDDFAKCGADQFTFHYE  106
                   +   +   A    H       +M  N       + +    A+ G D       
Sbjct  72   FAAGVTPAQCFEMLAAIRQKHPTIPIGLLMYANLVFSPGIDAFYAQCARVGVDSVLVADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDM  166
              ++     +      I       P    D+L ++A +      +    G  G +    +
Sbjct  132  PVEESAPFRQAAMRHNIAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAAL  191

Query  167  M--PKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA-----ADPHDV  219
                 VE L        +Q  G    E +  A  AGA   ++G+++         +P  +
Sbjct  192  PLHHLVEKLAEYHAAPPLQGFGISAPEQVSAAIDAGAAGAISGSAIVKIIERHLDEPQTM  251

Query  220  ISFMKEEVS  228
            +  +K  V 
Sbjct  252  LDELKAFVQ  260


>gi|73622050|sp|Q8DNM9|TRPA_STRR6  Tryptophan synthase alpha chain
Length=258

 Score =  131 bits (330),  Expect = 2e-30, Method: Composition-based stats.
 Identities = 33/245 (13%), Positives = 68/245 (27%), Gaps = 18/245 (7%)

Query  3    KPIIAPSILASDFAN----LGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRR  58
            K I  P I+A D       LG   H + + G   + + +    F   +  G  I  +  R
Sbjct  17   KGIFVPYIMAGDHEKGLDGLGETIHFLEDLGVSAIEVGI---PFSDPVADGPVIEEAGLR  73

Query  59   SVPRP---GDASNTEKKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEAT  108
            S+           T K         +M           E +V D A              
Sbjct  74   SLAHGTSTQALVETLKTIETEIPLVIMTYFNPLFQYGVENFVKDLADTAVKGLIIPDLPH  133

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDMM  167
            +    +   +    I     +   T ++   EL          + +    G        +
Sbjct  134  EHANFVEPFLADTDIALIPLVSLTTGIERQKELIEGAEGFVYAVAINGVTGKSGNYRADL  193

Query  168  PKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEV  227
             K      +   + +    G+  +   +   A ++ ++ G+ +  A    + I     + 
Sbjct  194  DKHLAQLHQVADIPVLTGFGVSSQADLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQA  253

Query  228  SKELR  232
                +
Sbjct  254  VAYQK  258


>gi|29428169|sp|P59457|TRPA_BUCBP  Tryptophan synthase alpha chain
Length=269

 Score =  131 bits (330),  Expect = 2e-30, Method: Composition-based stats.
 Identities = 31/223 (13%), Positives = 67/223 (30%), Gaps = 20/223 (8%)

Query  7    APSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPG  64
             P ++  D          + +I  GAD L + +    F   +  G  I  +  R+     
Sbjct  21   IPFVVLGDPSIEISLEIIYSLIKNGADGLELGI---PFSDPLADGPIIQQANLRAFSANI  77

Query  65   DASNTEKKP------TAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEATQDP  111
              +   +               +++          +K+    +K   D         ++ 
Sbjct  78   TLTKCFEMLFKIRTHNPKIPIGILIYANLIFKLGIQKFYSICSKIDIDSVLIADVPIEES  137

Query  112  LHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFMEDMMPK  169
                +      I +     P  S + L +L+ H    + +    G  G   K    +   
Sbjct  138  FEFEQHSIKNNIDSIFVCPPDASKNFLKKLSKHSTGYIYLLSRSGVTGIDMKITPPLKNF  197

Query  170  VETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
            V+ L+       IQ  G   +  I     +G + ++ G+ +  
Sbjct  198  VKELKKLTSIPIIQGFGISNENQIKNIILSGVSGVICGSVIIQ  240


>gi|73622013|sp|Q9RVT0|TRPA_DEIRA  Tryptophan synthase alpha chain
Length=270

 Score =  129 bits (325),  Expect = 7e-30, Method: Composition-based stats.
 Identities = 33/243 (13%), Positives = 77/243 (31%), Gaps = 20/243 (8%)

Query  6    IAPSILAS--DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
              P +     D A  G     ++ A AD + + +    +   +  G  I  +  +++   
Sbjct  31   FIPFMTGGYPDAARFGEVAGDLL-ARADIMEVGI---PYSDPLGDGPTIQRASEQALAGG  86

Query  64   GDASNTEKKPTA-----FFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEATQDP  111
                 T +              +M          P +++    + G D            
Sbjct  87   TSTRRTLELVRELRQKDDTPIVIMTYINPIYAVGPAEFMRLAQEAGVDGLILPDLPPDQD  146

Query  112  LHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDM--MPK  169
            L +  L    G+     I P ++ + +  +A      L      G  G +    +  +P+
Sbjct  147  LEIADLAAQHGLAVTFLIAPTSTPERVKLVAEACTGFLYAVSVTGVTGAREGAALGEVPR  206

Query  170  VETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSK  229
            +  L  ++    + V  G+      +     A+ +V G++   A      +  + +E++ 
Sbjct  207  MLDLARQYAQRPVVVGFGVKDAATAQQVAQVADGVVVGSAFINAVAAGRDVGALADELAA  266

Query  230  ELR  232
              R
Sbjct  267  GCR  269


>gi|28380204|sp|Q97P33|TRPA_STRPN  Tryptophan synthase alpha chain
Length=258

 Score =  129 bits (325),  Expect = 8e-30, Method: Composition-based stats.
 Identities = 32/245 (13%), Positives = 68/245 (27%), Gaps = 18/245 (7%)

Query  3    KPIIAPSILASDFAN----LGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRR  58
            K I  P I+A D       L    H + + G   + + +    F   +  G  I  +  R
Sbjct  17   KGIFVPYIMAGDHEKGLDGLAETIHFLEDLGVSAIEVGI---PFSDPVADGPVIEEAGLR  73

Query  59   SVPRP---GDASNTEKKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEAT  108
            S+           T K         +M           E +V D A              
Sbjct  74   SLAHGTSTQALVETLKTIETEIPLVIMTYFNPLFQYGVENFVKDLADTAVKGLIIPDLPH  133

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDMM  167
            +    +   + +  I     +   T ++   EL          + +    G        +
Sbjct  134  EHANFVEPFLANTDIALIPLVSLTTGIERQKELIEGAEGFIYAVAINGVTGKSGNYRADL  193

Query  168  PKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEV  227
             K      +   + +    G+  +   +   A ++ ++ G+ +  A    + I     + 
Sbjct  194  DKHLAQLHQVADIPVLTGFGVSSQADLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQA  253

Query  228  SKELR  232
                +
Sbjct  254  VAYQK  258


>gi|28380210|sp|Q9LAG8|TRPA_AZOBR  Tryptophan synthase alpha chain
Length=284

 Score =  129 bits (324),  Expect = 1e-29, Method: Composition-based stats.
 Identities = 33/225 (14%), Positives = 65/225 (28%), Gaps = 19/225 (8%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  +   I A D          H +  AGAD + + +    F   +  G  I  +  R++
Sbjct  26   RAGLVTFITAGDPDLETCRAVLHGLPAAGADLIELGL---PFSDPMADGPAIQAASLRAL  82

Query  61   PRPGDASNTEKKPTAF------FDCHMM-VENP------EKWVDDFAKCGADQFTFHYEA  107
                 A  T      F          +M   NP      ++++ D  + G D        
Sbjct  83   HAGTTARKTLDLVRGFRETDADTPVILMGYYNPIHAYGVDRFLADAIEAGVDGLIVVDLP  142

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPH-LDMALVMTVEPGFGGQKFMEDM  166
             ++   L       G+       P T    L  +  +       +++    G        
Sbjct  143  PEEDEELCIPALKAGVNFIRLATPTTDDKRLPAVLQNTSGFVYYVSIAGITGAASADNAA  202

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVF  211
            +        +   L + V  G+            A+  V G+++ 
Sbjct  203  VGAAVERLKRHTDLPVAVGFGIKTPEQAAEVARVADAAVVGSAIV  247


>gi|67461975|sp|Q71Z41|TRPA_LISMF  Tryptophan synthase alpha chain
Length=257

 Score =  129 bits (324),  Expect = 1e-29, Method: Composition-based stats.
 Identities = 29/242 (11%), Positives = 65/242 (26%), Gaps = 17/242 (7%)

Query  6    IAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            +   I+  D    NL  +   +  +G   + I +    F   +  G  I  +  R++   
Sbjct  17   VVTYIMGGDGGLDNLEEQLLFLEKSGVSAIEIGI---PFSDPVADGPIIQLAGLRALKEQ  73

Query  64   GDASNTEKKP---TAFFDCHMM-VENPE------KWVDDFAKCGADQFTFHYEATQDPLH  113
                    K           +M   NP       K+V+   K             +    
Sbjct  74   VSLEAILNKLARSKVQIPLIIMSYINPIFHLGIPKFVELVQKTPVKGLIIPDLPYEHQTL  133

Query  114  LVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDMMPKVET  172
            +   ++   I     +   +  + L E+A         +TV    G +   +  +     
Sbjct  134  ITPELQGTDIALIPLVSLTSPKERLEEIAKQAEGFIYAVTVNGTTGVRSEFDAHIDNHLA  193

Query  173  LRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELR  232
                   + +    G+      +      + ++ G+ V            +   + K   
Sbjct  194  YLKSISPVPVLAGFGVSSIEHVEKFAHVCDGVIIGSKVVQMLHEEKTA-ELGAFLQKAAE  252

Query  233  SR  234
             R
Sbjct  253  VR  254


>gi|20140605|sp|Q8Y6Q7|TRPA_LISMO  Tryptophan synthase alpha chain
Length=257

 Score =  129 bits (324),  Expect = 1e-29, Method: Composition-based stats.
 Identities = 28/242 (11%), Positives = 64/242 (26%), Gaps = 17/242 (7%)

Query  6    IAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            +   I+  D    NL  +   +  +G   + I +    F   +  G  I  +  R++   
Sbjct  17   VVTYIMGGDGGLDNLEEQLLFLEKSGVSAIEIGI---PFSDPVADGPIIQLAGLRALKEQ  73

Query  64   GDASNTE---KKPTAFFDCHMM-VENPE------KWVDDFAKCGADQFTFHYEATQDPLH  113
                                +M   NP       K+V+   K             +    
Sbjct  74   VSLEAILNKLAMSKVQIPLIIMSYINPIFHLGIPKFVELVQKTPVKGLIIPDLPYEHQKL  133

Query  114  LVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDMMPKVET  172
            +   ++   I     +   +  + L E+A         +TV    G +   +  +     
Sbjct  134  ITPELQGTDIALIPLVSLTSPKERLEEIAKQAEGFIYAVTVNGTTGVRSEFDAHIDSHLA  193

Query  173  LRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELR  232
                   + +    G+      +      + ++ G+ V            +   + K   
Sbjct  194  YLKSISPVPVLAGFGVSSIEHVEKFAHVCDGVIIGSKVVQMLHEEKTA-ELGAFLQKAAE  252

Query  233  SR  234
             R
Sbjct  253  VR  254


>gi|73622017|sp|Q5NE80|TRPA_FRATT  Tryptophan synthase alpha chain
Length=269

 Score =  128 bits (323),  Expect = 1e-29, Method: Composition-based stats.
 Identities = 33/250 (13%), Positives = 72/250 (28%), Gaps = 25/250 (10%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D   A        ++++GAD L + +    F   +  G  I  +  R+
Sbjct  16   NEGAFIPFVTIGDPNKALSFEIIDTLVSSGADALELGI---PFSDPLADGPTIQEANIRA  72

Query  60   V------PRPGDASNTEKKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYE  106
            +          D     +         +++          E +       G D       
Sbjct  73   LESGITPKDCFDILTKIRAKYPHIPIGLLLYANLVYANGIENFYQKCLDAGVDSILIADV  132

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGF--GGQKFME  164
               +      + K  GI       P  S   L +++        +    G          
Sbjct  133  PAHESKEFRDIAKKVGIAQIFIAPPDASESTLKQISELGSGYTYLLSRVGVTGTETAANM  192

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT-----AADPHDV  219
             +   +  LR       +   G    E + +A KAGA   ++G++         ++   +
Sbjct  193  PVEDVLTKLREYNAPKPVLGFGISKPEQVQQAIKAGAAGAISGSATVKIIQNNISNKQKM  252

Query  220  ISFMKEEVSK  229
            ++ +   V +
Sbjct  253  LNELTYFVKE  262


>gi|73622021|sp|Q5FRN3|TRPA_GLUOX  Tryptophan synthase alpha chain
Length=270

 Score =  128 bits (323),  Expect = 1e-29, Method: Composition-based stats.
 Identities = 34/226 (15%), Positives = 65/226 (28%), Gaps = 19/226 (8%)

Query  3    KPIIAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  + P + A D            +  AGAD + I V    F      G  I  +  R +
Sbjct  16   RGALIPYLQACDPDYDTSLELLRAMPAAGADLIEIGV---PFSDPSADGPTIQAAALRGL  72

Query  61   PRPGDASNTEKKPTAF------FDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEA  107
                      +   AF          +M          P ++  D A+ G D        
Sbjct  73   KAGATLGRVLEMVRAFRETDNETPIVLMGYLNPIDSYGPAEFCFDAAQAGVDGIIVVDMP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELA-PHLDMALVMTVEPGFGGQKFMEDM  166
            T++   L    +   +     + P TS   LF +          +++    G        
Sbjct  133  TEEADLLDAHAREADLDIISLVAPTTSNSRLFHVLREASGFVYYVSITGITGTNSASAAD  192

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
            + K      +   L + +  G+      + A    +  V  +++  
Sbjct  193  LEKALPRIREATSLPVAIGFGISTPEQARTASRIGDAAVVASALIK  238


>gi|7674400|sp|Q9ZJV0|TRPA_HELPJ  Tryptophan synthase alpha chain
Length=262

 Score =  128 bits (321),  Expect = 2e-29, Method: Composition-based stats.
 Identities = 36/244 (14%), Positives = 71/244 (29%), Gaps = 24/244 (9%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             K    P +   D            +I +G   L + +    F   +  G  I  S  R+
Sbjct  14   KKMAFIPFVTLGDPNYELSFEIVKTLIISGVSALELGLA---FSDPVADGTTIQASHLRA  70

Query  60   VPRP-----GDASNTEKKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEA  107
            +               +         ++           + +     +CG D        
Sbjct  71   LKHASMAKNFQLLKKIRGYNHDIPIGLLAYANLIFSYGVDGFYAQAKECGVDSVLIADMP  130

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--ED  165
              +   ++K  +   IK      P  S   L ++A H    +      G  G       D
Sbjct  131  LIEKELVIKSAQKHQIKQIFIASPNASSKDLEQVATHSQGYIYTLARSGVTGASHTLEND  190

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAA-----DPHDVI  220
                ++TL+       +   G   KE I  A   GA+ ++ G+++         +   ++
Sbjct  191  ASAIIKTLKTFSSTPALLGFGISKKEHITNAKGMGADGVICGSALVKIIEENLNNEDAML  250

Query  221  SFMK  224
              +K
Sbjct  251  EKIK  254


>gi|73621998|sp|Q8G691|TRPA_BIFLO  Tryptophan synthase alpha chain
Length=291

 Score =  128 bits (321),  Expect = 2e-29, Method: Composition-based stats.
 Identities = 27/238 (11%), Positives = 72/238 (30%), Gaps = 27/238 (11%)

Query  20   CECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKPTAF---  76
                 ++  G D + I +    +   +  G  I  +   ++          +        
Sbjct  55   DAFKTMVEHGVDAVEIGL---PYSDPVMDGPVIQAAASIALNNGETIKRVFEAVETVANA  111

Query  77   --FDCHMMV------ENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACA  128
                  M           E++  DF   G            +    ++     G+     
Sbjct  112  GGVPLIMSYWNLVYHYGVERFARDFENAGGAGLITPDLIPDEAGEWIEASDRHGLDRIFL  171

Query  129  IKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF-MEDMMPKVETLRAKFPHLNIQVDGG  187
            + P +S + L  +A +    +      G  G++  ++     +     +    N+ V  G
Sbjct  172  VSPDSSTERLETVARNARGFVYAAARMGVTGERATIDASPELLVERTRQAGAENVCVGIG  231

Query  188  LGKETIPKAAKAGANVIVAGTSVFT---------AADPHDVISFMK---EEVSKELRS  233
            +          + A+ ++ G+++           A DP + +  +    EE+++ + +
Sbjct  232  VSTAEQGAKVGSYADGVIVGSALVHTLLADDNKTARDPKEGLKLLAAKSEELAEGIHN  289


>gi|73622061|sp|Q5NPZ7|TRPA_ZYMMO  Tryptophan synthase alpha chain
Length=274

 Score =  127 bits (320),  Expect = 3e-29, Method: Composition-based stats.
 Identities = 35/254 (13%), Positives = 76/254 (29%), Gaps = 27/254 (10%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +  +   + A D            ++  G D + + +    F   +  G  I  +  R+
Sbjct  15   NRAALIAFLTAGDPSIEATPALLDSLVENGVDIIELGM---PFSDPMADGPAIQKANLRA  71

Query  60   VPRP------GDASNTEKKPTAFFDCHMM-VENP------EKWVDDFAKCGADQFTFHYE  106
            +            +   +K        +M   NP      + +     + G D       
Sbjct  72   LAAKTGYNDIFRIATEFRKRHPETPLILMGYANPMTFKGSDSFAASAKEAGVDGIICVDI  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMED  165
              ++   L   ++ KG+       P +    L  +          ++V    G Q+  E 
Sbjct  132  PPEEDATLGVAVREKGMDMIRLATPTSDEARLKIILDGASGFLYYVSVAGVTGLQQATEA  191

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGT--------SVFTAADPH  217
             +            L + V  G+       A    A+ +V G+        +V    DP+
Sbjct  192  SIDAALDRIKAVTDLPVAVGFGIRSPEQAAAIAKKADAVVVGSAFVSCIEKAVTNRQDPN  251

Query  218  DVISFMKEEVSKEL  231
              +  + +E+S  +
Sbjct  252  AALEKLAKELSTAI  265


>gi|38258768|sp|Q8CPB0|TRPA_STAES  Tryptophan synthase alpha chain
 gi|71153359|sp|Q5HPG9|TRPA_STAEQ  Tryptophan synthase alpha chain
Length=243

 Score =  127 bits (320),  Expect = 3e-29, Method: Composition-based stats.
 Identities = 38/241 (15%), Positives = 76/241 (31%), Gaps = 24/241 (9%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            M K  I P I+  D  N       +   GAD + I V    F   +  G  I+ + R ++
Sbjct  1    MSKLFI-PYIM-GDL-NFIHHLKTLTENGADIVEIGV---PFSDPVADGPIIMKAGRNAI  54

Query  61   PRPGDASNTEKKPTAFFD------CHMMVENP------EKWVDDFAKCGADQFTFHYEAT  108
                +      +     +        M   N       E ++D   + G           
Sbjct  55   DEGSNIKFIFDELIKNKNTISSKYVLMTYYNILSAYGEELFLDKCDEAGVYGLIIPDLPY  114

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVE--PGFGGQKFMEDM  166
            +      K      +K    I    S   + ++A + +  +             +F  D+
Sbjct  115  ELTKKFKKDFYHHSVKIISLIAMTASDARIMQIAKNSEGFIYTVTMNATTGNSGEFHPDL  174

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT---AADPHDVISFM  223
              K+E ++     + +    G+      K   + A+ IV G+ +          + I+++
Sbjct  175  KRKIEYIKK-VSKIPVVAGFGIKNPEHVKDIASVADGIVIGSEIVKRIEIDSRKEFITYI  233

Query  224  K  224
            K
Sbjct  234  K  234


>gi|20141970|sp|Q9HSB9|TRPA_HALSA  Tryptophan synthase alpha chain
Length=276

 Score =  127 bits (320),  Expect = 3e-29, Method: Composition-based stats.
 Identities = 36/254 (14%), Positives = 83/254 (32%), Gaps = 27/254 (10%)

Query  4    PIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVP  61
            P +   ++A D   A        +++ G D + + +    F   +  G  I  +++R++ 
Sbjct  14   PALVSYVVAGDPTPAATAEYIDALVDGGTDVIELGL---PFSEPVAEGTTIQNAIKRALD  70

Query  62   RPGD---ASNTEKKPTAFFDCH-MMVEN----------PEKWVDDFAKCGADQFTFHYEA  107
                     +   +  A      M   N          P  +V   A+ G   F      
Sbjct  71   AGMTPDAYLDLVARIDADVPVVCMTYYNLLFQYGDRAGPAAFVSAAAEAGVSGFVVPDLP  130

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMM  167
              +   L +  ++ G+     + P T+ D    +       + +    G  G +      
Sbjct  131  VDESGPLREACRAHGLDLVFVVAPTTTADRRERMLDLTTGFVYVQGRVGTTGAREEVSAA  190

Query  168  PKVETLRAKFPHLNIQVDGGLGK-ETIPKAAKAGANVIVAGTSVFTA-------ADPHDV  219
                    +   +   V  G+   E   +   +GA+ ++ G++            DP  V
Sbjct  191  TPDALAALQHTDIPKAVGFGVSSGEQAREITASGADGVIVGSAYVDTVADGVADDDPPSV  250

Query  220  ISFMKEEVSKELRS  233
            ++    +++ EL++
Sbjct  251  VADRLRDLAAELKA  264


>gi|267167|sp|Q01997|TRPA_LACLA  Tryptophan synthase alpha chain
Length=253

 Score =  127 bits (320),  Expect = 3e-29, Method: Composition-based stats.
 Identities = 35/245 (14%), Positives = 73/245 (29%), Gaps = 21/245 (8%)

Query  2    VKPIIAPSILASD----FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLR  57
             K    P I+A D       L      +  AG+  + I V    F   +  G  I  +  
Sbjct  11   KKNNFIPYIMAGDHEKGLEGLKETIQLLEQAGSSAIEIGV---PFSDPVADGPVIEQAGL  67

Query  58   RSVPRPG----DASNTEKKPTAFFDCHMMVENP------EKWVDDFAKCGADQFTFHYEA  107
            R++ R           +   T      M   NP      EK+V    K            
Sbjct  68   RALARNVSLSSILETLKTIDTKVPLVIMTYFNPVYQFGIEKFVAALEKTPVKGLIIPDLP  127

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDM  166
             +   ++   I  K I     +   T +    EL          + +    G +    + 
Sbjct  128  KEHEDYIKPFINDKDICLVPLVSLTTPLSRQKELVADAEGFIYAVAINGVTGKENAYSNQ  187

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT---AADPHDVISFM  223
            + +     +    + +    G+   +        ++ ++ G+ +         ++VI F+
Sbjct  188  LDQHLKALSSLTDVPVLTGFGISTLSDVDRFNKVSSGVIVGSKIVRDLHEGKENEVIKFI  247

Query  224  KEEVS  228
            +  ++
Sbjct  248  ENAIN  252


>gi|20140656|sp|Q92B82|TRPA_LISIN  Tryptophan synthase alpha chain
Length=257

 Score =  127 bits (319),  Expect = 4e-29, Method: Composition-based stats.
 Identities = 27/220 (12%), Positives = 60/220 (27%), Gaps = 16/220 (7%)

Query  6    IAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            +   I+  D    NL  +   +  +G   + I +    F   +  G  I  +  R++   
Sbjct  17   VVTYIMGGDGGLDNLEEQLLFLEKSGVSAIEIGI---PFSDPVADGPVIQLAGLRALKER  73

Query  64   GDASNTEKKP---TAFFDCHMM-VENPE------KWVDDFAKCGADQFTFHYEATQDPLH  113
                    K           +M   NP       K+++   K             +    
Sbjct  74   VSLEAILTKLATSKVQIPLIIMSYINPIFHLGIPKFIEMVQKTPVKGLIIPDLPYEHRTL  133

Query  114  LVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDMMPKVET  172
            +   +K   I     +   +  + L E+A         +TV    G +      +     
Sbjct  134  ITPELKGTDIALIPLVSLTSPKERLEEIANQAEGFIYAVTVNGTTGVRNEFNTHIDTHLA  193

Query  173  LRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
                   + +    G+      +      + ++ G+ V  
Sbjct  194  YLKSISPVPVLAGFGVSSIEHVEKFARVCDGVIIGSKVVQ  233


>gi|28380214|sp|Q9RCE7|TRPA_VIBME  Tryptophan synthase alpha chain
Length=268

 Score =  126 bits (318),  Expect = 5e-29, Method: Composition-based stats.
 Identities = 41/248 (16%), Positives = 76/248 (30%), Gaps = 23/248 (9%)

Query  2    VKPIIAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSL--R  57
             +    P +   D            ++ AGAD L + +    F   +  G  I  ++   
Sbjct  15   NQGAFVPFVTIGDPNPQQSLRIMQTLVEAGADALELGI---PFSDPLADGPTIQGAISAL  71

Query  58   RSVPRPGDASNTEKKPTAFFDC---HMMVEN------PEKWVDDFAKCGADQFTFHYEAT  108
             S  +P      ++ P    D     +M  N       + +     + G D        T
Sbjct  72   DSGTKPIRCFEADQAPIRAQDIPIYLLMYANLVYARGIDNFYQRCQQAGVDSVLIADVPT  131

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFMEDM  166
             +        K   I       P  S + L  +A        +    G  G   K    +
Sbjct  132  NESAEFGPAAKKYAIHPIFIAPPTASDETLQSVAELGSGYTYLLSRSGVTGAETKANMPV  191

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAAD-----PHDVIS  221
               +E L            G    E + +A ++GA   ++G++V    +     P  +++
Sbjct  192  HALLERLNQFSAPPRRLGFGISEPEQVKQAIESGAAGAISGSAVVKIIEHHLAKPEAMLA  251

Query  222  FMKEEVSK  229
             +K  VS 
Sbjct  252  ELKTFVSA  259


>gi|28380215|sp|Q9RQ33|TRPA_BUCMH  Tryptophan synthase alpha chain
Length=270

 Score =  126 bits (318),  Expect = 5e-29, Method: Composition-based stats.
 Identities = 36/228 (15%), Positives = 69/228 (30%), Gaps = 20/228 (8%)

Query  2    VKPIIAPSILASDFAN--LGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             K    P ++  D +        + +I  GAD L + +    F   I  G+ I  +  R+
Sbjct  15   KKGCFIPFVVLGDPSIDMSLKIINALIENGADGLELGI---PFSDPIADGEIIQKANLRA  71

Query  60   VPRPGDASNTEKKPTAFFDCH-------MMVEN------PEKWVDDFAKCGADQFTFHYE  106
                 +        +   + H       ++  N        K+     K G D       
Sbjct  72   FNSKINLHKCFDILSEIREKHQTIPIGLLLYSNLIFKFGINKFYLKCYKIGIDSILIADL  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG--GQKFME  164
              ++     K      I       P    +V+  +A H    + +    G     Q+ M 
Sbjct  132  PIEESYVFRKYAVINNILPVFICPPDAKKNVIKNIAIHSQGYIYLLSRSGVTGINQEIMI  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
              +  +  L+       IQ  G      I K   +G + ++ G+ +  
Sbjct  192  PPLSLINKLKKLTKTPLIQGFGVSYPYQIQKIILSGISGVICGSIIAK  239


>gi|29611887|sp|Q8D8B1|TRPA_VIBVU  Tryptophan synthase alpha chain
Length=268

 Score =  126 bits (317),  Expect = 6e-29, Method: Composition-based stats.
 Identities = 40/249 (16%), Positives = 78/249 (31%), Gaps = 25/249 (10%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D            ++ AGAD L + +    F   +  G  I  +  R+
Sbjct  15   KQGAFVPFVTVCDPNPELSLKIMDTLVKAGADALELGI---PFSDPLADGPTIQGANIRA  71

Query  60   VP---RPGDASNTEKKPTAFFD----CHMMVEN------PEKWVDDFAKCGADQFTFHYE  106
            +     P    +   +  A +       +M  N       E +    A+ G D       
Sbjct  72   LDSGATPDICFDLIGQIRAKYPDLPIGLLMYANLVYSRGIENFYQRCAQAGIDSVLIADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFME  164
             T +    V   +  G+       P  S + L +++        +    G  G   K   
Sbjct  132  PTNESAEFVAAAEKFGVHPIFIAPPTASDETLKQVSQLGGGYTYLLSRAGVTGAETKANM  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAA-----DPHDV  219
             +   +  L        +   G    E + +A  AGA   ++G++V         +P  +
Sbjct  192  PVGDMLAKLEQFNAPPALLGFGISEPEQVKQAIDAGAAGAISGSAVVKIIESHLNEPDAM  251

Query  220  ISFMKEEVS  228
            ++ +   VS
Sbjct  252  LTALANFVS  260


>gi|56749770|sp|Q7MM57|TRPA_VIBVY  Tryptophan synthase alpha chain
Length=268

 Score =  126 bits (317),  Expect = 7e-29, Method: Composition-based stats.
 Identities = 40/249 (16%), Positives = 78/249 (31%), Gaps = 25/249 (10%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D            ++ AGAD L + +    F   +  G  I  +  R+
Sbjct  15   KQGAFVPFVTVCDPNPELSLKIMDTLVQAGADALELGI---PFSDPLADGPTIQGANIRA  71

Query  60   VP---RPGDASNTEKKPTAFFD----CHMMVEN------PEKWVDDFAKCGADQFTFHYE  106
            +     P    +   +  A +       +M  N       E +    A+ G D       
Sbjct  72   LDSGATPDICFDLIGQIRAKYPDLPIGLLMYANLVYSRGIENFYQRCAQAGIDSVLIADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFME  164
             T +    V   +  G+       P  S + L +++        +    G  G   K   
Sbjct  132  PTNESAEFVAAAEKFGVHPIFIAPPTASDETLKQVSQLGGGYTYLLSRAGVTGAETKANM  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAA-----DPHDV  219
             +   +  L        +   G    E + +A  AGA   ++G++V         +P  +
Sbjct  192  PVGDMLAKLEQFNAPPALLGFGISEPEQVKQAIDAGAAGAISGSAVVKIIESHLNEPDAM  251

Query  220  ISFMKEEVS  228
            ++ +   VS
Sbjct  252  LTALANFVS  260


>gi|73622058|sp|Q7M877|TRPA_WOLSU  Tryptophan synthase alpha chain
Length=255

 Score =  126 bits (317),  Expect = 7e-29, Method: Composition-based stats.
 Identities = 32/224 (14%), Positives = 70/224 (31%), Gaps = 18/224 (8%)

Query  1    MVKPIIAPSILAS--DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRR  58
            M K  +   I A+  D          +  +G D L + V    F   +  G  I  +   
Sbjct  9    MKK--LVAYITAALPDKEFTIDLALALSASGVDSLELGV---PFSDPVADGPIIEHANLL  63

Query  59   SVPRPGDASN---TEKKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEAT  108
            ++ +     +     +K +   D   M           E+        G           
Sbjct  64   ALQKGFSLQDLYEITEKISPSIDTLWMGYLNPFHKVGFEQTCQKAKSLGVSGLIIPDVPF  123

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMP  168
            ++     +      +     I P      +  +AP     + +    G  G    E + P
Sbjct  124  EESAPFEEQCLQNNLALIRFIAPTLGTSRIATIAPMARKFIYLVAYAGITGSGREEPLSP  183

Query  169  KVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
             +E +RA  P + + +  G+ +    + +K   + ++ G+++  
Sbjct  184  LIEEIRAINPEIPLYLGFGVNEHNAKEKSKE-VDGVIVGSALVK  226


>gi|73622004|sp|Q62AJ6|TRPA_BURMA  Tryptophan synthase alpha chain
Length=271

 Score =  126 bits (316),  Expect = 8e-29, Method: Composition-based stats.
 Identities = 38/254 (14%), Positives = 81/254 (31%), Gaps = 27/254 (10%)

Query  3    KPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  + P I A D   A      H +   GAD + + V    F   +  G  I  S  R++
Sbjct  16   RKGLIPFITAGDPDPAKTVELMHALAEGGADVIELGV---PFSDPMADGPVIQRSSERAL  72

Query  61   PRPGDASNTEKKPTAF------FDCHMM-VENPEKWV------DDFAKCGADQFTFHYEA  107
             +     +       F          +M   NP + +            G D        
Sbjct  73   AKGVTLHSVLDDVKRFRARDQKTPVVLMGYANPIERMGADAFAAAARDAGVDGVLVVDYP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFME--D  165
             ++       +++ GI     + P ++ D +  +       +      G  G   ++   
Sbjct  133  PEESHDFAAKMRAAGIDPIFLLAPTSTDDRIAAVGQVASGYVYYVSLKGVTGAANLDVSS  192

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAAD---PHDVISF  222
            +  K+  ++++ P L + V  G+      +A    A+ +V G+ +    +   P    + 
Sbjct  193  IAGKIPAIKSRVP-LPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLLEQAVPERAAAE  251

Query  223  ---MKEEVSKELRS  233
                  E+   +  
Sbjct  252  LAGFVAELRAAIDG  265


>gi|73622022|sp|Q5V140|TRPA_HALMA  Tryptophan synthase alpha chain
Length=293

 Score =  125 bits (315),  Expect = 1e-28, Method: Composition-based stats.
 Identities = 41/276 (14%), Positives = 77/276 (27%), Gaps = 48/276 (17%)

Query  4    PIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVP  61
            P   P + A D            +   GAD + + +    F   I  G+ I  ++ RS+ 
Sbjct  11   PAFVPYLAAGDPNYEASLEYVEALARGGADVIELGL---PFSEPIAEGKTIQNAIVRSLE  67

Query  62   RPGD----ASNTEKKPTAFFDCHMMVEN---------------------------PEKWV  90
                        E          M   N                           P  +V
Sbjct  68   AGMTPDRFFQFVEDLDVDVPLVCMTYYNLIYQYGEGDSESRSDSENASGETASQGPRPFV  127

Query  91   DDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALV  150
            +  A  G +         ++   L        +     + P T  D L  +   +   + 
Sbjct  128  EKAAAVGIEGLVVPDLPGEEAGPLRTACDEFDLDLVFIVAPTTKGDRLERMLEQVSGYVY  187

Query  151  MTVEPGFGGQKF--MEDMMPKVETLRAKFPHLNIQVDGGLGK-ETIPKAAKAGANVIVAG  207
            +    G  G +    +     +  L      +   V  G+       +   AGA+ I+ G
Sbjct  188  VQARLGVTGAREDVDDATEDSLARLSDW--DVPKAVGFGIKTGAHAERIVSAGADGIIVG  245

Query  208  TSVF-------TAADPHDVISFMKEEVSKELRSRDL  236
            +++           D  D ++   E  ++EL+   L
Sbjct  246  SALVDIVAEGHENGDSTDAVADRLEAKARELKEGAL  281


>gi|14195299|sp|Q9TLW8|TRP1_CYACA  Tryptophan synthase alpha chain
Length=266

 Score =  125 bits (315),  Expect = 1e-28, Method: Composition-based stats.
 Identities = 24/208 (11%), Positives = 62/208 (29%), Gaps = 17/208 (8%)

Query  19   GCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEK-------  71
                  +   GA+ + + +    +   +  G  I  +  +++    +     K       
Sbjct  32   KQAIIAMDKNGANIIELGI---PYSDPVADGPVIQDAYNKAIKNGVNIRKAFKILMNLKG  88

Query  72   KPTAFFDCHMMV-----ENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAA  126
            K  +     +           K+++   +              +   L K      I   
Sbjct  89   KIKSPIIVFIYYNQLLNYGINKFLEKLIQLEVQGIIVPDLPYDESQILKKKCTINNIALI  148

Query  127  CAIKPGTSVDVLFELAPHLDMALVMTVEPGFG--GQKFMEDMMPKVETLRAKFPHLNIQV  184
              I   +S   + ++A + +  L +  + G      K M  +   ++T++       +  
Sbjct  149  SLIALTSSFSRIKKIARNAEGFLYLISKTGVTGGTGKLMNKLKIIIKTIQKLTSKPVVVG  208

Query  185  DGGLGKETIPKAAKAGANVIVAGTSVFT  212
             G   +  I +  +  +N IV G+    
Sbjct  209  FGINSRRQIKQLIEWNSNGIVIGSPCVQ  236


>gi|1174782|sp|P43759|TRPA_HAEIN  Tryptophan synthase alpha chain
Length=268

 Score =  125 bits (314),  Expect = 1e-28, Method: Composition-based stats.
 Identities = 32/233 (13%), Positives = 67/233 (28%), Gaps = 21/233 (9%)

Query  2    VKPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D  F         +++ GAD L +      F   +  G  I  +  R+
Sbjct  15   NEGAFVPFVTLCDPTFDRSFEIICTLVDNGADALELGF---PFSDPLLDGPVIQAANNRA  71

Query  60   VPRP------GDASNTEKKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYE  106
            +                +         +++          + +    A+ G D       
Sbjct  72   LTAGHSSEDSLKLLEKVRSKYPEIPISLLLCANLIFAKGLDAFYQRCAEVGVDAVLVADI  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG---GQKFM  163
                    V+  K  GI+      P      +  +A + +    +    G      Q   
Sbjct  132  PLLAKGDYVQTAKKHGIQPVFICPPNADEKTIQGVAKNSEGYTYLVSRAGVTSAENQAHA  191

Query  164  EDMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADP  216
             ++   VE L+A      +Q  G    E + +A   G    ++G++     + 
Sbjct  192  ANLDTLVEKLKAHNAPPILQGFGIAQPEQVKEALSLGTAGAISGSATVKIIER  244


>gi|7674382|sp|Q44604|TRPA_BUCSC  Tryptophan synthase alpha chain
Length=269

 Score =  124 bits (313),  Expect = 2e-28, Method: Composition-based stats.
 Identities = 34/258 (13%), Positives = 81/258 (31%), Gaps = 26/258 (10%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             K    P I+  D            +I  GAD L +      F   ++ G+ I  +  R+
Sbjct  15   KKGCFIPFIILGDPSIEMSLKIIDVLIENGADGLELGF---PFSDPLSDGKTIQKAHLRA  71

Query  60   VP------RPGDASNTEKKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYE  106
                       +     +K        +++            +       G D       
Sbjct  72   FSSKMNIYLCFEMLQKIRKKYNTIPIGLLLYANLIFKFGINNFYLKCFNVGIDSVLIADL  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFME  164
              ++     K   +  I +          +V+ +++ +    + +    G  G   K + 
Sbjct  132  PVEESNDFRKCAIANNISSVFVCPHDAKKNVIKKISLYSTGYIYLLSRSGVTGTDKKIIV  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA-----ADPHDV  219
              +  ++ L+     L IQ  G    + I K   +G + ++ G+ +         +   +
Sbjct  192  PSLNLIKNLKKITEKLLIQGFGISNSKQIQKIILSGISGVICGSVIIKLIENHFQNEKKM  251

Query  220  ISFMKEEVSKELRSRDLL  237
            +  +K  +S+ L+   ++
Sbjct  252  LKNIKR-LSRSLKQSTII  268


>gi|73622005|sp|Q63JM0|TRPA_BURPS  Tryptophan synthase alpha chain
Length=271

 Score =  124 bits (313),  Expect = 2e-28, Method: Composition-based stats.
 Identities = 39/254 (15%), Positives = 81/254 (31%), Gaps = 27/254 (10%)

Query  3    KPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  + P I A D   A      H +   GAD + + V    F   +  G  I  S  R++
Sbjct  16   RKGLIPFITAGDPDPAKTVELMHALAEGGADVIELGV---PFSDPMADGPVIQRSSERAL  72

Query  61   PRPGDASNTEKKPTAF------FDCHMM-VENPEKWV------DDFAKCGADQFTFHYEA  107
             +     +       F          +M   NP + +            G D        
Sbjct  73   AKGVTLHSVLDDVKRFRARDQKTPVVLMGYANPIERMGADAFAAAARDAGVDGVLVVDYP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFME--D  165
             ++       +++ GI     + P ++ D +  +       +      G  G   ++   
Sbjct  133  PEESHDFAAKMRAAGIDPIFLLAPTSTDDRIAAVGQVASGYVYYVSLKGVTGAANLDVSS  192

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA---ADPHDVISF  222
            +  K+  ++++ P L + V  G+      +A    A+ +V G+ +      A P    + 
Sbjct  193  IAGKIPAIKSRVP-LPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLLEQAAPERAAAE  251

Query  223  ---MKEEVSKELRS  233
                  E+   +  
Sbjct  252  LAGFVAELRVAIDG  265


>gi|28380178|sp|Q8KEZ7|TRPA_CHLTE  Tryptophan synthase alpha chain
Length=267

 Score =  124 bits (311),  Expect = 3e-28, Method: Composition-based stats.
 Identities = 33/248 (13%), Positives = 71/248 (28%), Gaps = 32/248 (12%)

Query  2    VKPIIAPSI-LASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
             K +IA  +               +  +G D + + +    +   I  G  I  +  +++
Sbjct  14   KKLLIAYYMPEFPVPGATLPVLEALQESGVDLIELGM---PYSDPIGDGSVIQDAAHKAI  70

Query  61   PRPGDASNTEKKP----------TAFFDCHMM-VENP------EKWVDDFAKCGADQFTF  103
                   +  +                   +M   NP      + ++ D  K G D    
Sbjct  71   SHGVHVGSIFELVRRARNGEGCKKITTPILLMGYCNPLIAYGGDCFMADAVKAGVDGLLI  130

Query  104  HYEATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAP---HLDMALVMTVEPGFGG-  159
                 ++    ++  K  G+     I P T  D +  +          L +    G G  
Sbjct  131  PDLPPEESEDFLERAKHFGLSVIYLISPVTPPDRIELIDSMSTDFSYCLAVNATTGTGKL  190

Query  160  --QKFMEDMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT----A  213
                  E +   ++ +R       + V  G+      +     A+  V G+++      A
Sbjct  191  DVAGMDEKIAEYLKRVRQHTKKKFV-VGFGIKDRERVRKMWELADGAVVGSALLQHVATA  249

Query  214  ADPHDVIS  221
              P +   
Sbjct  250  KTPEETAE  257


>gi|2501408|sp|P56141|TRPA_HELPY  Tryptophan synthase alpha chain
Length=262

 Score =  124 bits (311),  Expect = 4e-28, Method: Composition-based stats.
 Identities = 37/229 (16%), Positives = 70/229 (30%), Gaps = 19/229 (8%)

Query  3    KPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K    P +   D            +I +G   L + +    F   +  G  I  S  R++
Sbjct  15   KMAFIPFVTLGDPNYELSFEIIKTLIISGVSALELGLA---FSDPVADGITIQASHLRAL  71

Query  61   PRP-----GDASNTEKKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEAT  108
                           +         ++           + +     +CG D         
Sbjct  72   KHASMAKNFQLLKKIRDYNHNIPIGLLAYANLIFSYGVDGFYAQAKECGIDSVLIADMPL  131

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--EDM  166
             +   ++K  +   IK      P  S   L ++A H    +      G  G   +   D 
Sbjct  132  IEKELVIKSAQKHQIKQIFIASPNASSKDLEQVATHSQGYIYALARSGVTGASRILENDS  191

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAAD  215
               ++TL+A  P   +   G   KE I  A   GA+ ++ G+++    +
Sbjct  192  SAIIKTLKAFSPTPALLGFGISKKEHITNAKGMGADGVICGSALVKIIE  240


>gi|29611946|sp|P22095|TRPA_VIBPA  Tryptophan synthase alpha chain
Length=268

 Score =  124 bits (311),  Expect = 4e-28, Method: Composition-based stats.
 Identities = 36/231 (15%), Positives = 70/231 (30%), Gaps = 20/231 (8%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D            ++ +GAD L + +    F   +  G  I  +  R+
Sbjct  15   NQGAFVPFVTVCDPNAEQSYKIMETLVESGADALELGI---PFSDPLADGPTIQGANIRA  71

Query  60   VPRPGDASNTEKKPT------AFFDC-HMMVEN------PEKWVDDFAKCGADQFTFHYE  106
            +          ++               +M  N       E + +  AK G D       
Sbjct  72   LDSGATPDICFEQIGKIRAKYPDLPIGLLMYANLVYSRGIESFYERCAKAGIDSVLIADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFME  164
             T +    V   +  GI       P  S + L +++        +    G  G   K   
Sbjct  132  PTNESAEFVAAAEKFGIHPIFIAPPTASDETLKQVSELGGGYTYLLSRAGVTGAETKANM  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAAD  215
             +   +E L        +   G      + +A +AGA   ++G++V    +
Sbjct  192  PVDHMLEKLNQFNAPPALLGFGISEPAQVKQAIEAGAAGAISGSAVVKIIE  242


>gi|73622031|sp|Q740P2|TRPA_MYCPA  Tryptophan synthase alpha chain
Length=271

 Score =  123 bits (310),  Expect = 4e-28, Method: Composition-based stats.
 Identities = 30/237 (12%), Positives = 67/237 (28%), Gaps = 19/237 (8%)

Query  14   DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKP  73
            D          ++ +G D + + V    +      G  I  +   ++       +T    
Sbjct  36   DVPTSVQAMVALVESGCDIVEVGV---PYSDPGMDGPTIARATEAALHGGVRVRDTLAAV  92

Query  74   TAF-----FDCHMMVENP------EKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKG  122
             A          M   NP      + +  D A  G            +    +   +  G
Sbjct  93   EAISAAGGRAVVMTYWNPVLRYGVDAFARDLAAAGGYGLITPDLIPDEAGQWLAASERHG  152

Query  123  IKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--EDMMPKVETLRAKFPHL  180
            +     + P ++   L          +      G  G +          V  +R     +
Sbjct  153  LDRIFLVAPSSTPQRLALTVEASRGFVYAASTMGVTGARDAVSHAAPELVSRVRE-ISDI  211

Query  181  NIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA--ADPHDVISFMKEEVSKELRSRD  235
             + V  G+            A+ ++ G+++ +A        +  + EE++  +R R 
Sbjct  212  PVGVGLGVRSREQAAQIGGYADGVIVGSALVSALGDGGLTALRALTEELAAGVRQRA  268


>gi|73622010|sp|Q6NEB5|TRPA_CORDI  Tryptophan synthase alpha chain
Length=278

 Score =  123 bits (310),  Expect = 4e-28, Method: Composition-based stats.
 Identities = 38/236 (16%), Positives = 72/236 (30%), Gaps = 21/236 (8%)

Query  2    VKPIIAPSIL--ASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P I+  A            V+ AGAD L + V    F   +  G  I  S  R+
Sbjct  15   NEGAFVPFIMLGAPTPEASLAIIRTVVAAGADALELGV---PFSDPVADGPTIQRSHLRA  71

Query  60   VPRPGDASNTEKKPT------AFFDCHMMVEN-------PEKWVDDFAKCGADQFTFHYE  106
            +       ++ +               M++           ++  +FA  G D       
Sbjct  72   LDNGATVDSSLELIRQIRKEFPELPIGMLIYGNVAFTRGITQFYQEFADAGVDSILLPDV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPH-LDMALVMTVE--PGFGGQKFM  163
              ++    +   K  GI          S   L  +A H       ++ +   G   Q   
Sbjct  132  PVREGEPFIAAAKQAGIDPIFIAPAQASEATLEGVAQHSSGYIYAISRDGVTGTERQSST  191

Query  164  EDMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDV  219
              +   V  ++       +   G    E +  A  AGA+  + G+++ +  + H  
Sbjct  192  RGLDKVVANVKRFGGAPILLGFGISTPEHVRDAIAAGASGAITGSALTSIIERHTT  247


>gi|73622015|sp|Q72EU7|TRPA_DESVH  Tryptophan synthase alpha chain
Length=257

 Score =  123 bits (309),  Expect = 5e-28, Method: Composition-based stats.
 Identities = 30/242 (12%), Positives = 75/242 (30%), Gaps = 18/242 (7%)

Query  3    KPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +P + P + A          E   +  AGAD + + V    F   +  G  +  + +R++
Sbjct  18   RPALIPFLTAGFPTKERFWDELEALDAAGADIIEVGV---PFSDPVADGPVVAAASQRAL  74

Query  61   PRPGDAS---NTEKKPTAFFDCHM---------MVENPEKWVDDFAKCGADQFTFHYEAT  108
                      +            +         M    E++V D A  G           
Sbjct  75   ESGVTLRWIMDGLAARKGRLRAGLVLMGYLNPFMQYGFERFVSDAADAGVAGCIIPDLPL  134

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAP-HLDMALVMTVEPGFGGQKFMEDMM  167
             +   L  L+ ++ +     + P T    + E A        V++V    G +  +   +
Sbjct  135  DEDADLRALLAARDMDLIALVGPNTGEGRMREYAAVASGYVYVVSVMGTTGVRDGLPVEV  194

Query  168  PKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEV  227
                    +   + + +  G+ +    +      + ++ G+++    D     +   +  
Sbjct  195  ADTLARARQCFSIPVALGFGISRPAQLEGLSHPPDAVIFGSALLRHLDAGGDAASFMKAW  254

Query  228  SK  229
            ++
Sbjct  255  AE  256


>gi|73622037|sp|Q6LPA3|TRPA_PHOPR  Tryptophan synthase alpha chain
Length=269

 Score =  123 bits (309),  Expect = 6e-28, Method: Composition-based stats.
 Identities = 35/231 (15%), Positives = 70/231 (30%), Gaps = 20/231 (8%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D            ++ +GAD L + +    F   +  G  I  +  R+
Sbjct  15   NEGAFVPFVTIGDPTPEQSMKIIDTLVASGADALELGI---PFSDPLADGPTIQAATIRA  71

Query  60   V---PRPGDASNTEKKPTAFFD----CHMMVEN------PEKWVDDFAKCGADQFTFHYE  106
            +     P        +  A +       +M  N       E +    A  G D       
Sbjct  72   LESGTTPIVCFELLTQIRAKYPDMPIGLLMYANLVFTAGIETFYKKCADAGVDSVLIADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFME  164
              ++        +  GI       P  + + L  ++        +    G  G   K  +
Sbjct  132  PIKESEEFRVAAEKYGIHPIFIAPPNATDETLKSVSELGGGYTYLLSRAGVTGAETKAGK  191

Query  165  DMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAAD  215
             +   VE+L        +   G      + +A +AGA   ++G++V    +
Sbjct  192  PIRHLVESLTKHNAPPALLGFGISEPAQVKEAIEAGAAGAISGSAVVKIIE  242


>gi|47606774|sp|P16608|TRPA_THET2  Tryptophan synthase alpha chain
Length=271

 Score =  123 bits (309),  Expect = 6e-28, Method: Composition-based stats.
 Identities = 37/246 (15%), Positives = 86/246 (34%), Gaps = 22/246 (8%)

Query  3    KPIIAPSILASDFANLGCECHKVINA--GADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  + P + A   +  G     V      AD L I +    +   +  G  I  +   ++
Sbjct  15   RAALIPYLTAGFPSREG-FLQAVEEVLPYADLLEIGL---PYSDPLGDGPVIQRASELAL  70

Query  61   PRPGDASNTEKKPTAFF-----DCHMMVE-------NPEKWVDDFAKCGADQFTFHYEAT  108
             +        +              +M          PE++   F + GA          
Sbjct  71   RKGMSVQGALELVREVRALTEKPLFLMTYLNPVLAWGPERFFGLFKQAGATGVILPDLPP  130

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG--GQKFMEDM  166
             +   LV+L +  G++    + P ++   +  +  H    +      G     ++  E++
Sbjct  131  DEDPGLVRLAQEIGLETVFLLAPTSTDARIATVVRHATGFVYAVSVTGVTGMRERLPEEV  190

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
               V  ++A+   L + V  G+       A  A A+ +V G+++  A +    ++ + +E
Sbjct  191  KDLVRRIKARTA-LPVAVGFGVSG-KATAAQAAVADGVVVGSALVRALEEGRSLAPLLQE  248

Query  227  VSKELR  232
            + + L+
Sbjct  249  IRQGLQ  254


>gi|73622014|sp|Q6AMR6|TRPA_DESPS  Tryptophan synthase alpha chain
Length=254

 Score =  123 bits (309),  Expect = 6e-28, Method: Composition-based stats.
 Identities = 26/229 (11%), Positives = 61/229 (26%), Gaps = 18/229 (7%)

Query  15   FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKPT  74
            FA       +++  G D +    M   F   +  G  I+ + + S+ R    +       
Sbjct  29   FAANREVIEQMVKNGVDCIE---MQIPFSEPMADGPVILKANQESLARGTRVAQCFDFAR  85

Query  75   A-----FFDCHMM-VENP------EKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKG  122
                        M   N       E++  D  + G           +         +   
Sbjct  86   EMTRKHQIPFLFMTYYNIVFKYGEERFFQDAKEAGIKGLIVPDLPPEMGEDYFAYAEQYQ  145

Query  123  IKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG-GQKFMEDMMPKVETLRAKFPHLN  181
            +       P ++ + +  LA      +      G       +++      +       L 
Sbjct  146  LAPIIIYAPTSTPERMKTLAGSATGFIYCAARRGVTGNNSALDENFDNYLSNCRAATTLP  205

Query  182  IQVDGGLGKETIPKAAKAGANVIVAGTSVFTA--ADPHDVISFMKEEVS  228
            + V  G+  +   +A    A++ V G+        +    +      + 
Sbjct  206  LAVGFGIKSKADVQALIGKADMAVIGSQTIRLVDENGPKAVGPFVASLR  254


>gi|73622034|sp|Q5YYN3|TRPA_NOCFA  Tryptophan synthase alpha chain
Length=266

 Score =  123 bits (308),  Expect = 7e-28, Method: Composition-based stats.
 Identities = 33/238 (13%), Positives = 77/238 (32%), Gaps = 18/238 (7%)

Query  14   DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKP  73
            D A     C  ++ +G D + + V    +   +  G  I  +  +++       +     
Sbjct  32   DLAGSIATCRAMVESGCDIVEVGVA---YSDPVMDGPTIQAAAEQALRGGVRVRDVFSVV  88

Query  74   TAFFD-----CHMMVENP------EKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKG  122
             A          M   NP      E++  D A  G           ++         +  
Sbjct  89   EAITAAGGQAVVMSYWNPVLRYGVERFARDLAAAGGAGIITPNLIPEEADDWFIASATHN  148

Query  123  IKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--EDMMPKVETLRAKFPHL  180
            +     + P ++ + L +        +      G  G +             +RA    +
Sbjct  149  LDRIFLVAPSSTEERLVKTLEASRGFIYAASTMGVTGARDAVSSAAPALCARIRAH-SDI  207

Query  181  NIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAA-DPHDVISFMKEEVSKELRSRDLL  237
             I V  G+          + A+ ++ G+++ +AA +  D +  +  E+++ +RS  + 
Sbjct  208  PIGVGLGVRNGAQAAEIASYADGVIVGSALVSAAGEGLDAVRALTSELAEGVRSATVA  265


>gi|20140857|sp|Q9KST7|TRPA_VIBCH  Tryptophan synthase alpha chain
Length=268

 Score =  123 bits (308),  Expect = 7e-28, Method: Composition-based stats.
 Identities = 37/246 (15%), Positives = 75/246 (30%), Gaps = 25/246 (10%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D            +I+AGAD L + +    F   +  G  I  +  R+
Sbjct  15   QQGAFVPFVTIGDPNPEQSLAIMQTLIDAGADALELGM---PFSDPLADGPTIQGANLRA  71

Query  60   VPRPGDASNTEKKP------TAFFDC-HMMVEN------PEKWVDDFAKCGADQFTFHYE  106
            +          +                +M  N       + +     K G D       
Sbjct  72   LAAKTTPDICFELIAQIRARNPETPIGLLMYANLVYARGIDDFYQRCQKAGVDSVLIADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDM  166
             T +    V   +  GI+      P  S + L  +A        +    G  G +   +M
Sbjct  132  PTNESQPFVAAAEKFGIQPIFIAPPTASDETLRAVAQLGKGYTYLLSRAGVTGAETKANM  191

Query  167  -MPKVETLRAKFPHLNIQVDGGLG-KETIPKAAKAGANVIVAGTSVFTA-----ADPHDV  219
             +  +     +F      +  G+     + +A +AGA   ++G++V         +P   
Sbjct  192  PVHALLERLQQFDAPPALLGFGISEPAQVKQAIEAGAAGAISGSAVVKIIETHLDNPAKQ  251

Query  220  ISFMKE  225
            ++ +  
Sbjct  252  LTELAN  257


>gi|73622056|sp|Q5SJC0|TRPA_THET8  Tryptophan synthase alpha chain
Length=271

 Score =  123 bits (308),  Expect = 7e-28, Method: Composition-based stats.
 Identities = 37/246 (15%), Positives = 86/246 (34%), Gaps = 22/246 (8%)

Query  3    KPIIAPSILASDFANLGCECHKVINA--GADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +  + P + A   +  G     V      AD L I +    +   +  G  I  +   ++
Sbjct  15   RAALIPYLTAGFPSREG-FLQAVEEVLPYADLLEIGL---PYSDPLGDGPVIQRASELAL  70

Query  61   PRPGDASNTEKKPTAFF-----DCHMMVE-------NPEKWVDDFAKCGADQFTFHYEAT  108
             +        +              +M          PE++   F + GA          
Sbjct  71   RKGMSVQGALELVREVRALTEKPLFLMTYLNPVLAWGPERFFGLFKQAGATGVILPDLPP  130

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFG--GQKFMEDM  166
             +   LV+L +  G++    + P ++   +  +  H    +      G     ++  E++
Sbjct  131  DEDPGLVRLAQEIGLETVFLLAPTSTDARIATVVRHATGFVYAVSVTGVTGMRERLPEEV  190

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEE  226
               V  ++A+   L + V  G+       A  A A+ +V G+++  A +    ++ + +E
Sbjct  191  KDLVRRIKARTA-LPVAVGFGVSG-KATAAQAAVADGVVVGSALVRALEEGRSLAPLLQE  248

Query  227  VSKELR  232
            + + L+
Sbjct  249  IRQGLQ  254


>gi|136256|sp|P12291|TRPA_CAUCR  Tryptophan synthase alpha chain
Length=275

 Score =  123 bits (308),  Expect = 8e-28, Method: Composition-based stats.
 Identities = 39/244 (15%), Positives = 73/244 (29%), Gaps = 22/244 (9%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +      ++A D   A        +  AGAD + +      F   +  G  I  + +R 
Sbjct  17   NRAGFVTYVMAGDPDAATTLSVLKGLPAAGADLIELGF---PFSDPMAEGPTIQRAAQRG  73

Query  60   VPRPGDASNTEKKPTAF------FDCHMMVE-------NPEKWVDDFAKCGADQFTFHYE  106
            +        T     AF          +M           E +    AK G D       
Sbjct  74   LKSGMTLQGTLDLVAAFREGDQDTPIILMGYLNPVLNKGFETFAALAAKAGVDGLIIVDC  133

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPH-LDMALVMTVEPGFGGQKFMED  165
              ++   L   ++++GI       P T    L  +          ++V    G +     
Sbjct  134  PPEEADPLSDALEAEGIALIRLAAPTTDDARLPMVVRRTSGFVYYVSVAGVTGVKSADAA  193

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKE  225
             +        K   L + V  G+       A    A+  V G+++    D  +  + + E
Sbjct  194  DVAPAVERLRKASGLPVAVGFGIRTPDQAAAVAKVADAAVVGSALV---DEIESAAQLNE  250

Query  226  EVSK  229
             V++
Sbjct  251  NVTE  254


>gi|3915157|sp|O13831|TRP_SCHPO  Tryptophan synthase
Length=697

 Score =  121 bits (304),  Expect = 2e-27, Method: Composition-based stats.
 Identities = 26/213 (12%), Positives = 58/213 (27%), Gaps = 22/213 (10%)

Query  2    VKPIIAPSILAS--DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             K ++   +     +          + N GA  + + +    F   +  G  I      +
Sbjct  16   NKNVLVTFVTCGFPNVDETIKIMQGLQNGGAGIIELGI---PFSDAVADGPTICKGNEIA  72

Query  60   VPRPGDASNTEKKPT------AFFDCHMM-VENPE------KWVDDFAKCGADQFTFHYE  106
            +          +               +M   NP       K +    + GA+ F     
Sbjct  73   LKNNITLEKVFETVKLARDAGVTIPIILMGYYNPIFSYGDAKTIQKAKEVGANGFIIVDL  132

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF----  162
              ++ +   +  K +G+     + P T+   +  LA   D  + +    G  G       
Sbjct  133  PPEEAVGFREECKKQGVSFVPLVAPSTTDRRMELLASVADSFIYVVSRMGSTGSSATGVI  192

Query  163  MEDMMPKVETLRAKFPHLNIQVDGGLGKETIPK  195
               +    + +R       + V  G+       
Sbjct  193  NTALPQLCQRVRKFAGDTPLAVGFGVNTSEHFH  225


>gi|6226270|sp|O68906|TRPA_MYCIT  Tryptophan synthase alpha chain
Length=271

 Score =  121 bits (303),  Expect = 2e-27, Method: Composition-based stats.
 Identities = 29/237 (12%), Positives = 67/237 (28%), Gaps = 19/237 (8%)

Query  14   DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKP  73
            D          ++ +G D + + V    +      G  IV +   ++       +T    
Sbjct  36   DVTTSVHAMVALVESGCDIVEVGV---PYSDPGMDGPTIVKATEAALHGGVRVRDTLAAV  92

Query  74   TAF-----FDCHMMVENP------EKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKG  122
             A          M   NP      + +  D A  G            +    +   +   
Sbjct  93   EAISAAGGHAVVMTYWNPVLRYGIDAFARDLASAGGYGLITPDLIPDEAGQWLAASEEHR  152

Query  123  IKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--FMEDMMPKVETLRAKFPHL  180
            +     + P ++   L          +      G  G +          V  ++     +
Sbjct  153  LDRIFLVAPSSTPQRLAMTVEASRGFVYAASTMGVTGARDVVSNAAPELVGRVKE-ISDI  211

Query  181  NIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA--ADPHDVISFMKEEVSKELRSRD  235
             + V  G+            A+ ++ G+++ +A        +  + EE++  +R R 
Sbjct  212  PVGVGLGVRSGEQAAQIGGYADGVIVGSALVSALGDGGLTALRALTEELAAGVRQRA  268


>gi|20140627|sp|Q8ZEH0|TRPA_YERPE  Tryptophan synthase alpha chain
Length=268

 Score =  120 bits (302),  Expect = 4e-27, Method: Composition-based stats.
 Identities = 33/210 (15%), Positives = 58/210 (27%), Gaps = 20/210 (9%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D   A        +I AGAD L + +    F   +  G  I  +  R+
Sbjct  15   KEGAFVPFVQLGDPSPAMSLNIIDTLIAAGADALELGI---PFSDPLADGPTIQNAALRA  71

Query  60   VPRP------GDASNTEKKPTAFFDC-HMMVEN------PEKWVDDFAKCGADQFTFHYE  106
                       +     ++         +M  N       + +    A+ G D       
Sbjct  72   FAAGVTPGICFEILAEIRQKHPTIPIGLLMYANLVFHNGIDHFYQRCAEVGVDSVLIADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDM  166
              ++           GI       P    D+L E+A H      +    G  G +    +
Sbjct  132  PFEESAPFRAAALRHGIAPIFICPPNADDDLLREIASHGRGYTYLLSRAGVTGAENHGQL  191

Query  167  M--PKVETLRAKFPHLNIQVDGGLGKETIP  194
                 V+ LR       +Q  G      + 
Sbjct  192  PLNHLVDKLREYNAAPALQGFGISEPAQVK  221


>gi|73622000|sp|Q7W5G9|TRPA_BORPA  Tryptophan synthase alpha chain
Length=285

 Score =  120 bits (302),  Expect = 4e-27, Method: Composition-based stats.
 Identities = 32/224 (14%), Positives = 74/224 (33%), Gaps = 21/224 (9%)

Query  6    IAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            + P I A D +        H ++ AGAD + + V    F   +  G  +  +  R++ + 
Sbjct  23   LIPYIAAGDPSPQATVPLMHALVRAGADLVELGV---PFSDPMADGPVVQRAAERAIAQG  79

Query  64   GDASNT------EKKPTAFFDCHMM-VENPEKWV------DDFAKCGADQFTFHYEATQD  110
                         ++  +     +M   NP + +            G D         ++
Sbjct  80   VGLRRVLELVADFRRDDSVTPVVLMGYANPIERMGQRAFAQAAQAAGVDGVLVVDYPPEE  139

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--EDMMP  168
                  ++   G+     + P ++   +  +       +      G  G   +  +D+  
Sbjct  140  VDEFAAMLAEAGVAPIFLLAPTSTEARIEAIGRVARGYVYYVSLKGVTGAGSLDTDDVAR  199

Query  169  KVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
            K+  +R    H+ + V  G+      +   A A+ +V G+ +  
Sbjct  200  KLALIRRHV-HIPVGVGFGIRDAASAQRIAAHADAVVIGSKLIE  242


>gi|73622060|sp|Q66AK5|TRPA_YERPS  Tryptophan synthase alpha chain
Length=268

 Score =  119 bits (300),  Expect = 6e-27, Method: Composition-based stats.
 Identities = 33/210 (15%), Positives = 58/210 (27%), Gaps = 20/210 (9%)

Query  2    VKPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
             +    P +   D   A        +I AGAD L + +    F   +  G  I  +  R+
Sbjct  15   KEGAFVPFVQLGDPSPAMSLNIIDTLIAAGADALELGI---PFSDPLADGPTIQNAALRA  71

Query  60   VPRP------GDASNTEKKPTAFFDC-HMMVEN------PEKWVDDFAKCGADQFTFHYE  106
                       +     ++         +M  N       + +    A+ G D       
Sbjct  72   FAAGVTPAICFEILAEIRQKHPTIPIGLLMYANLVFHNGIDHFYQRCAEVGVDSVLIADV  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDM  166
              ++           GI       P    D+L E+A H      +    G  G +    +
Sbjct  132  PFEESAPFRAAALRHGIAPIFICPPNADDDLLREIASHGRGYTYLLSRAGVTGAENHGQL  191

Query  167  M--PKVETLRAKFPHLNIQVDGGLGKETIP  194
                 V+ LR       +Q  G      + 
Sbjct  192  PLNHLVDKLREYNAAPALQGFGISEPAQVK  221


>gi|73622052|sp|Q5M351|TRPA_STRT2  Tryptophan synthase alpha chain
Length=260

 Score =  119 bits (300),  Expect = 6e-27, Method: Composition-based stats.
 Identities = 32/226 (14%), Positives = 70/226 (30%), Gaps = 18/226 (7%)

Query  2    VKPIIAPSILASDFAN----LGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLR  57
             + I  P I+A D A     L      + N+G   + + +    +   +  G  I  + +
Sbjct  16   KRGIFVPYIMAGDHAKGLDGLFETITLLENSGVSAIEVGI---PWSDPVADGPIIELAGQ  72

Query  58   RSVPRPGDASNTEKK---PTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEA  107
            RS+ +    +   KK           +M           E +V D A+            
Sbjct  73   RSLAKDVTLTAIIKKLQEKKTQVPLVIMTYINPVYQYGIEAFVKDLAETSVKGLIIPDLP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDM  166
             +    +   ++   I     +   T +D   +L          + +    G      D 
Sbjct  133  NEHADFITPYLRDSDIALVPLVSLTTGIDRQKQLIDGAEGFIYAVAINGVTGKTGNYRDD  192

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
            + K  +    +  + +    G+  E   K   A ++ ++ G+ +  
Sbjct  193  LDKHLSNLTAYADIPVLTGFGVSTEEDIKRFNAVSDGVIVGSKIVR  238


>gi|73621999|sp|Q7WD05|TRPA_BORBR  Tryptophan synthase alpha chain
Length=285

 Score =  119 bits (300),  Expect = 6e-27, Method: Composition-based stats.
 Identities = 32/245 (13%), Positives = 80/245 (32%), Gaps = 21/245 (8%)

Query  6    IAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            + P I A D +        H ++ AGAD + + V    F   +  G  +  +  R++ + 
Sbjct  23   LIPYIAAGDPSPQATVPLMHALVRAGADLVELGV---PFSDPMADGPVVQRAAERAIAQG  79

Query  64   GDASNT------EKKPTAFFDCHMM-VENPEKWV------DDFAKCGADQFTFHYEATQD  110
                         ++  +     +M   NP + +            G D         ++
Sbjct  80   VGLRRVLELVADFRRDDSVTPVVLMGYANPIERMGQRAFAQAAQAAGVDGVLVVDYPPEE  139

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--EDMMP  168
                  ++   G+     + P ++   +  +       +      G  G   +  +D+  
Sbjct  140  VDEFAAMLAEAGVAPIFLLAPTSTEARIEAIGRVARGYVYYVSLKGVTGAGSLDTDDVAR  199

Query  169  KVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVS  228
            K+  +R    H+ + V  G+      +   A A+ +V G+ +    +     +   ++  
Sbjct  200  KLALIRRHV-HIPVGVGFGIRDAASAQRIAAHADAVVIGSKLIETMEQAGAQAGADQKNE  258

Query  229  KELRS  233
              + +
Sbjct  259  AAIAA  263


>gi|73622046|sp|Q8ECU9|TRPA_SHEON  Tryptophan synthase alpha chain
Length=278

 Score =  119 bits (300),  Expect = 7e-27, Method: Composition-based stats.
 Identities = 30/230 (13%), Positives = 67/230 (29%), Gaps = 20/230 (8%)

Query  3    KPIIAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            +    P +   D            ++  GAD L +      F   +  G  I  +  R++
Sbjct  28   RGAFVPFVTLGDPSPELSLKIIDTLVQNGADALELGF---PFSDPLADGPVIQGANLRAL  84

Query  61   PRP------GDASNTEKKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEA  107
                      +     +         +++          + +     + G D        
Sbjct  85   AAGTTPTACFELLAKIRAKYPELPIGLLLYANLVFANGIDAFYAKAQQAGVDSVLIADVP  144

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQ--KFMED  165
             ++    ++  K+ GI       P    D L +++   +    +    G  G   K    
Sbjct  145  VEEAAPFIQAAKAHGIAPIFIAPPNADSDTLAKVSQSGEGYTYLLSRAGVTGADTKAGTP  204

Query  166  MMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAAD  215
            +   +  L+       +   G      +  A KAGA   ++G++V    +
Sbjct  205  VEEILAKLQEFNAPPPLLGFGIAEPAQVSAAIKAGAAGAISGSAVVKIIE  254


>gi|73622051|sp|Q5LYI8|TRPA_STRT1  Tryptophan synthase alpha chain
Length=260

 Score =  119 bits (299),  Expect = 8e-27, Method: Composition-based stats.
 Identities = 32/226 (14%), Positives = 70/226 (30%), Gaps = 18/226 (7%)

Query  2    VKPIIAPSILASDFAN----LGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLR  57
             + I  P I+A D A     L      + N+G   + + +    +   +  G  I  + +
Sbjct  16   KRGIFVPYIMAGDHAKGLDGLFETITLLENSGVSAIEVGI---PWSDPVADGPIIELAGQ  72

Query  58   RSVPRPGDASNTEKK---PTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEA  107
            RS+ +    +   KK           +M           E +V D A+            
Sbjct  73   RSLAKDVTLTAIIKKLQEKKTQVPLVIMTYINPVYEYGIEAFVKDLAETSVKGLIIPDLP  132

Query  108  TQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHL-DMALVMTVEPGFGGQKFMEDM  166
             +    +   ++   I     +   T +D   +L          + +    G      D 
Sbjct  133  NEHADFITPYLRDSDIALVPLVSLTTGIDRQKQLINGAEGFIYAVAINGVTGKTGNYRDD  192

Query  167  MPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
            + K  +    +  + +    G+  E   K   A ++ ++ G+ +  
Sbjct  193  LDKHLSNLTAYADIPVLTGFGVSTEEDIKRFNAVSDGVIVGSKIVR  238


>gi|73622001|sp|Q7VTF0|TRPA_BORPE  Tryptophan synthase alpha chain
Length=285

 Score =  119 bits (299),  Expect = 8e-27, Method: Composition-based stats.
 Identities = 32/245 (13%), Positives = 80/245 (32%), Gaps = 21/245 (8%)

Query  6    IAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
            + P I A D +        H ++ AGAD + + V    F   +  G  +  +  R++ + 
Sbjct  23   LIPYIAAGDPSPQATVPLMHALVRAGADLVELGV---PFSDPMADGPVVQRAAERAIAQG  79

Query  64   GDASNT------EKKPTAFFDCHMM-VENPEKWV------DDFAKCGADQFTFHYEATQD  110
                         ++  +     +M   NP + +            G D         ++
Sbjct  80   VGLRRVLELVADFRRDDSVTPVVLMGYANPIERMGQRAFAQAAQAAGVDGVLVVDYPPEE  139

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--EDMMP  168
                  ++   G+     + P ++   +  +       +      G  G   +  +D+  
Sbjct  140  VDEFAVMLAEAGVAPIFLLAPTSTEARIEAIGRVARGYVYYVSLKGVTGAGSLDTDDVAR  199

Query  169  KVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVS  228
            K+  +R    H+ + V  G+      +   A A+ +V G+ +    +     +   ++  
Sbjct  200  KLALIRRHV-HIPVGVGFGIRDAASAQRIAAHADAVVIGSKLIETMEQAGAQAGADQKNE  258

Query  229  KELRS  233
              + +
Sbjct  259  AAIAA  263


>gi|38258753|sp|Q88WH9|TRPA_LACPL  Tryptophan synthase alpha chain
Length=265

 Score =  119 bits (299),  Expect = 9e-27, Method: Composition-based stats.
 Identities = 33/252 (13%), Positives = 71/252 (28%), Gaps = 23/252 (9%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K  IA  ++A D  F     +   +  AG D + I +    F   +  G  I  +  R+ 
Sbjct  13   KAFIA-FVVAGDPNFEATVDQVVALAEAGCDLVEIGI---PFSDPVADGPEIQAADLRAF  68

Query  61   P------RPGDASNTEKKPTAFFDCHMMVENPEK------WVDDFAKCGADQFTFHYEAT  108
                   R  +     ++ T      +   N         +                   
Sbjct  69   DQHITPQRVFELVVAIREKTTIPLVFLTYANIVYQFGYAAFAQQCQSLNVAGLIIPDMPL  128

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSV-DVLFELAPHLDMALVMTVEPGFGGQKFMEDMM  167
            +    L   +   GI     I P +    +            V++     G ++ +   +
Sbjct  129  EASGELRPTLDHYGIALIPLIAPTSDDARIAAIAQQARGFIYVVSSLGVTGTRRHITTDL  188

Query  168  PKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAA---DPHDVI-SFM  223
              +         L + +  G+ +    +A    A+ ++ G++V        P   +    
Sbjct  189  ATLVAKIRHATTLPVAIGFGIHEPAQAQAMAQIADGVIVGSAVVHLIATHQPATAVLRDY  248

Query  224  KEEVSKELRSRD  235
               + + L  R 
Sbjct  249  TRRMRRALDGRT  260


>gi|51316365|sp|Q7VRI8|METE_BLOFL  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=769

 Score =  118 bits (297),  Expect = 1e-26, Method: Composition-based stats.
 Identities = 34/201 (16%), Positives = 69/201 (34%), Gaps = 34/201 (16%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              +  E   +  +G   + ID       P +  G P+  S      +        + +  
Sbjct  589  LAIRDEVMDLEKSGIGVIQID------EPALREGLPLKKSEQSYYLKWAINTFKITVSSV  642

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K       HM      + +DD  K   D  +   E+++  L L++ IK+ G K       
Sbjct  643  KDNTQIHTHMCYSEFNEIIDDILKLDVDVISI--ESSRSDLQLLQFIKTAGKKL------  694

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +              Q  + ++M K++ L    P   L I  D GL 
Sbjct  695  ----NEIGPGIYDIHSI----------HQPSINEIMDKLKKLLQYIPKDRLWINPDCGLK  740

Query  190  KETIPKAAKAGANVIVAGTSV  210
              +  +  ++  N+++A  ++
Sbjct  741  TRSWNEIRESLNNMVIAAKTL  761


>gi|33301707|sp|Q822W2|TRPA_CHLCV  Tryptophan synthase alpha chain
Length=257

 Score =  116 bits (291),  Expect = 7e-26, Method: Composition-based stats.
 Identities = 39/229 (17%), Positives = 69/229 (30%), Gaps = 24/229 (10%)

Query  3    KPIIAPSILASD--FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            KP I   +   D  F       H +I  G D L I      F   +  G  I  +  R++
Sbjct  12   KPFIG-YLTGGDGGFDYSVACAHALIRGGVDILEIGF---PFSDPVADGPIIQKAHTRAL  67

Query  61   PRPGDASNTEKKPTAFFD------CHMMVENPE-----KWVDDFAKCGADQFTFHYEATQ  109
                D++   +   A  +            NP      +++      G D          
Sbjct  68   EEKTDSTTILEIAKALRETSNIPLVLFSYYNPLLQKGPQYLHQLKAAGFDAVLIVDLPIP  127

Query  110  ----DPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--  163
                +     + +    +       P T  + L ++       L    + G  G +    
Sbjct  128  QHANESEPFFQALIEAKLFPIVLATPSTREERLLQIRKLAKGFLYYVSQKGTTGIRSKLS  187

Query  164  EDMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
            +D   ++  LR  F  + I    G+       AA   A+ IV G++   
Sbjct  188  DDFSTQIARLRCYF-QIPIVAGFGIANRASAAAALKHADGIVVGSAFVE  235


>gi|20140766|sp|Q9CC53|TRPA_MYCLE  Tryptophan synthase alpha chain
Length=270

 Score =  115 bits (289),  Expect = 1e-25, Method: Composition-based stats.
 Identities = 28/237 (11%), Positives = 72/237 (30%), Gaps = 16/237 (6%)

Query  14   DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKP  73
            D         +++ +G D + + V    +      G  I  +   ++       +T    
Sbjct  37   DVPTSVDAMIELVESGCDIIEVGV---PYSDPGMDGPTIARATEVALRGGVRVRDTLAAV  93

Query  74   TAF-----FDCHMMVENPE------KWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKG  122
             A          M   NP        +  D    G            +    +   +   
Sbjct  94   EAISQAGGRAVVMTYWNPVLRYGVCAFARDLESAGGHGLVTPDLIPDEARQWIAASEKHR  153

Query  123  IKAACAIKPGTSVDVL-FELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLN  181
            +     + P ++   L   +         ++V    G +  +  ++P++         + 
Sbjct  154  LDRIFLVAPSSTPHRLVTTVGASRGFVYAVSVMGVTGARDAVSQVVPELVARVKAVSDIA  213

Query  182  IQVDGGLGKETIPKAAKAGANVIVAGTSVFTA-ADPHDVISFMKEEVSKELRSRDLL  237
            + V  G+            A+ ++ G+++ +A  D    +  + EE++  +R R  +
Sbjct  214  VGVGLGVRSREQAAQIGGYADGVIVGSALVSALGDGLPRLRALAEELAAGVRQRTFM  270


>gi|30173100|sp|Q8ZAL3|METE_YERPE  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=758

 Score =  114 bits (287),  Expect = 2e-25, Method: Composition-based stats.
 Identities = 31/198 (15%), Positives = 60/198 (30%), Gaps = 35/198 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              L  E   +  AG   + ID       P +  G P+  +      +        +    
Sbjct  582  LALRDEVEDLEKAGIGIIQID------EPALREGLPLRRADWQAYLQWAVDAFKLNAAVA  635

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            +       HM        +D  A   AD  T   E ++  + L++           + + 
Sbjct  636  QNDTQIHTHMCYCEFNDIMDSIAALDADVITI--ETSRSDMELLE-----------SFED  682

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +    V +V          E +   +     + P   L +  D GL 
Sbjct  683  FAYPNEIGPGVYDIHSPNVPSV----------EWIEALLRKAAQRIPAERLWVNPDCGLK  732

Query  190  KETIPKAAKAGANVIVAG  207
                P+  +A AN+++A 
Sbjct  733  TRGWPETRQALANMVLAA  750


>gi|73622049|sp|Q8DVF2|TRPA_STRMU  Tryptophan synthase alpha chain
Length=260

 Score =  114 bits (286),  Expect = 3e-25, Method: Composition-based stats.
 Identities = 29/248 (11%), Positives = 70/248 (28%), Gaps = 21/248 (8%)

Query  3    KPIIAPSILASD----FANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRR  58
            K +  P I+A D       L      +   G   + I +    +   +  G  I  + +R
Sbjct  17   KGLFIPYIMAGDHDKGLDGLFDTISFLEAQGVSAIEIGI---PWSDPVADGPVIELAGQR  73

Query  59   SVPRPGDASNTEKK---PTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEAT  108
            S+ +    ++   +           +M           E +V D                
Sbjct  74   SLVKGTSLASIIARLQEKKTQVPLVIMTYFNPVFQYGVETFVADLQNTSVKGLIIPDLPH  133

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMP  168
            +    +   +++  +     +   T ++   EL       +   V       K       
Sbjct  134  EQESFIKPYLENLDLALVPLVSLTTGLERQKELIEDARGFVY-AVAINGVTGKTGNYRDD  192

Query  169  KVETLRAKFPHLNIQVDGGLGKETIPKAAKAG--ANVIVAGTSVFTAADPHDVISFMKEE  226
              + L+       I V  G G  T+    +    ++ ++ G+ +        +   +K+ 
Sbjct  193  LDKHLKHLTEIAQIPVLTGFGVSTLADIKRFNQVSDGVIVGSKIVKGLH-EGMQEEIKDF  251

Query  227  VSKELRSR  234
            +      +
Sbjct  252  IYAGSHYQ  259


>gi|73622006|sp|Q9PIF1|TRPA_CAMJE  Tryptophan synthase alpha chain
 gi|73622007|sp|Q5HWB8|TRPA_CAMJR  Tryptophan synthase alpha chain
Length=249

 Score =  113 bits (284),  Expect = 4e-25, Method: Composition-based stats.
 Identities = 35/211 (16%), Positives = 74/211 (35%), Gaps = 16/211 (7%)

Query  14   DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTE---  70
            +         ++  +  D L + V    +   I  G+ I  + + ++ +  D  +     
Sbjct  23   NLQTSEAFLQRLDQSPIDILELGVA---YSDPIADGEIIADAAKIALDQGVDIHSVFELL  79

Query  71   KKPTAFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGI  123
             +         MV          EK+V      G         + ++   L+K  +   I
Sbjct  80   ARIKTKKALVFMVYYNLIFSYGLEKFVKKAKSLGICALIVPELSFEESDDLIKECERYNI  139

Query  124  KAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMM--PKVETLRAKFPHLN  181
                 +   T  + + +L  H    + +    G  G K +E+ +   KV+ +R+   +L 
Sbjct  140  ALITLVSVTTPKERVKKLVKHAKGFIYLLASIGITGTKSVEEAILQDKVKEIRSFT-NLP  198

Query  182  IQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
            I V  G+      K  +  A+ ++ GTS+  
Sbjct  199  IFVGFGIQNNQDVKRMRKVADGVIVGTSIVK  229


>gi|71658020|sp|Q6AF66|TRPA_LEIXX  Tryptophan synthase alpha chain
Length=261

 Score =  113 bits (282),  Expect = 8e-25, Method: Composition-based stats.
 Identities = 28/234 (11%), Positives = 63/234 (26%), Gaps = 20/234 (8%)

Query  14   DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKP  73
            D          +   G D + + +    +   +  G  I  + +R++       +     
Sbjct  29   DLRTSVDAAVALAENGVDVIELGL---PYSDPVMDGAVIQAATQRALANGFRLRDGFAAV  85

Query  74   TAFF------DCHMMVENP------EKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSK  121
                         M   NP      +++ DDFA  G            +    +   +  
Sbjct  86   REITSRVDAPVLVMTYWNPVMQYGVDRFADDFATAGGAGLITPDLIPDEGADWLAASERT  145

Query  122  GIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQK--FMEDMMPKVETLRAKFPH  179
            G+       P ++     + A +    +      G  G +          V  LR     
Sbjct  146  GLDRVFLAAPSSTEARRRQTAANSRGFVYAVSTMGITGVRTDVDAAARTLVGRLREAGAL  205

Query  180  LNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT--AADPHDVISFMKEEVSKEL  231
                  G      + +     A+  + G+++ T  A         +  E+++  
Sbjct  206  SACVGLGISSAAQVAEVLDY-ADGAIVGSALVTALAKGGVAAAGRIAAELARGA  258


>gi|51316315|sp|Q7MZ74|METE_PHOLL  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=758

 Score =  113 bits (282),  Expect = 8e-25, Method: Composition-based stats.
 Identities = 32/217 (14%), Positives = 59/217 (27%), Gaps = 44/217 (20%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              L  E   +  AG   + ID       P +  G P+      S           +    
Sbjct  582  LALRDEVDDLQEAGIGIIQID------EPALREGLPLRREEWQSYLDWAVEAFKLNAAIA  635

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K       HM        +   A   AD  T   E ++  + L+   ++           
Sbjct  636  KDDTQIHTHMCYCEFNDIMPSIAALDADVITI--ETSRSDMELLDSFENF----------  683

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKE  191
             +  + +      +    V +VE      +   D +P           L +  D GL   
Sbjct  684  -SYPNEIGPGVYDIHSPNVPSVEWIEALLRKAADRIP--------VERLWVNPDCGLKTR  734

Query  192  TIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVS  228
               +  ++ AN++                  ++E V 
Sbjct  735  GWTETRQSLANMV-------------QAAKRLRESVK  758


>gi|51316415|sp|Q83IW0|METE_SHIFL  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=753

 Score =  112 bits (281),  Expect = 9e-25, Method: Composition-based stats.
 Identities = 32/198 (16%), Positives = 58/198 (29%), Gaps = 35/198 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              L  E   +  AG   + ID       P +  G P+      +  +        +    
Sbjct  579  LALRDEVADLEAAGIGIIQID------EPALREGLPLRRSDWDAYLQWGVEAFRINAAVA  632

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K       HM        +D  A   AD  T   E ++  + L++  +            
Sbjct  633  KDDTQIHTHMCYCEFNDIMDSIAALDADVITI--ETSRSDMELLESFEEFD---------  681

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +    V +V          E +   ++    + P   L +  D GL 
Sbjct  682  --YPNEIGPGVYDIHSPNVPSV----------EWIEALLKKAAKRIPAERLWVNPDCGLK  729

Query  190  KETIPKAAKAGANVIVAG  207
                P+   A AN++ A 
Sbjct  730  TRGWPETRAALANMVQAA  747


>gi|30173118|sp|Q9AMV8|METE_BRAJA  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=781

 Score =  112 bits (281),  Expect = 9e-25, Method: Composition-based stats.
 Identities = 29/208 (13%), Positives = 57/208 (27%), Gaps = 35/208 (16%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              +  E   + NAGA  + ID         +  G P+      +            ++  
Sbjct  601  LAMRDEVRDLENAGAAMIQID------EAALREGLPLRRSDWKAYLDWAGDCFRICSSGV  654

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
                    HM        +   A   AD  +   E ++  + L+   +            
Sbjct  655  TDQTQIHTHMCYSEFNDIIGAIAAMDADVISI--ETSRSKMELLDAFRRY----------  702

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKF--PHLNIQVDGGLG  189
                        + +       +         ++M   +   R +     L +  D GL 
Sbjct  703  -----------EYPNQIGPGVYDIHSPRVPETDEMKELIVLARTRLQDSQLWVNPDCGLK  751

Query  190  KETIPKAAKAGANVIVAGTSVFTAADPH  217
                 +   A AN++ A   +  A+DP 
Sbjct  752  TRKWEEVRPALANMVAAARELRAASDPQ  779


>gi|30173098|sp|Q8Z3B6|METE_SALTI  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=754

 Score =  112 bits (281),  Expect = 1e-24, Method: Composition-based stats.
 Identities = 33/205 (16%), Positives = 61/205 (29%), Gaps = 35/205 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              L  E   +  AG   + ID       P +  G P+      +           +    
Sbjct  579  LALRDEVADLEAAGIGIIQID------EPALREGLPLRRSDWDAYLEWGVEAFRINAAVA  632

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K       HM        +D  A   AD  T   E ++  + L++  ++           
Sbjct  633  KDETQIHTHMCYCEFNDIMDSIAALDADVITI--ETSRSDMELLESFEAFD---------  681

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +    V +V          E +   ++    + P   L +  D GL 
Sbjct  682  --YPNEIGPGVYDIHSPNVPSV----------EWIEALLKKAAQRIPAQRLWVNPDCGLK  729

Query  190  KETIPKAAKAGANVIVAGTSVFTAA  214
                P+   A AN++ A  ++  A 
Sbjct  730  TRGWPETRAALANMVKAAHNLRQAK  754


>gi|6226718|sp|P50908|TRPA_THEMA  Tryptophan synthase alpha chain
Length=239

 Score =  112 bits (281),  Expect = 1e-24, Method: Composition-based stats.
 Identities = 36/247 (14%), Positives = 78/247 (31%), Gaps = 29/247 (11%)

Query  3    KPIIAPSILAS--DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            K  IA  I A   D          +   G   + I V    F   +  G  I  +   ++
Sbjct  2    KGFIA-YIPAGFPDLETTRKILIALNELGITGVEIGV---PFSDPVADGPVIQLAHSVAL  57

Query  61   PRPGDASNTEKK---PTAFFDCHMM-VENP--------EKWVDDFAKCGADQFTFHYEAT  108
                      +     +  +D ++M   NP        EK +D+  K G           
Sbjct  58   RNGVTIKKILEMLSEISVDYDLYLMSYLNPIVNYPEGKEKLLDELKKLGVKGLIIPDLPL  117

Query  109  QDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAP-HLDMALVMTVEPGFGGQKFMEDMM  167
            ++  ++              + P T  + +  +          ++   G  G++      
Sbjct  118  REVKNVDIA-----YPIVPFVAPNTKDEEIDLINSVQAPFVYYISRY-GVTGEREDLPFA  171

Query  168  PKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTA--ADPHDVI-SFMK  224
              ++ ++ +         G    E + K  +  A+ ++ G+++      +P D I   + 
Sbjct  172  DHIKRVKERIKLPLFVGFGISRHEQVKKVWEI-ADGVIVGSALVRIMEENPKDEIPRKVV  230

Query  225  EEVSKEL  231
            E+V + L
Sbjct  231  EKVKELL  237


>gi|30173093|sp|Q8X8L5|METE_ECO57  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=753

 Score =  112 bits (280),  Expect = 1e-24, Method: Composition-based stats.
 Identities = 32/198 (16%), Positives = 58/198 (29%), Gaps = 35/198 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              L  E   +  AG   + ID       P +  G P+      +  +        +    
Sbjct  579  LALRDEVADLEAAGIGIIQID------EPALREGLPLRRSDWDAYLQWGVEAFRINAAVA  632

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K       HM        +D  A   AD  T   E ++  + L++  +            
Sbjct  633  KDDTQIHTHMCYCEFNDIMDSIAALDADVITI--ETSRSDMELLESFEEFD---------  681

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +    V +V          E +   ++    + P   L +  D GL 
Sbjct  682  --YPNEIGPGVYDIHSPNVPSV----------EWIEALLKKAAKRIPAERLWVNPDCGLK  729

Query  190  KETIPKAAKAGANVIVAG  207
                P+   A AN++ A 
Sbjct  730  TRGWPETRAALANMVQAA  747


>gi|73622008|sp|Q7VQZ9|TRPA_BLOFL  Tryptophan synthase alpha chain
Length=271

 Score =  112 bits (280),  Expect = 1e-24, Method: Composition-based stats.
 Identities = 35/249 (14%), Positives = 75/249 (30%), Gaps = 24/249 (9%)

Query  2    VKPIIAPSILASDFA--NLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRS  59
                  P I   D            +I +GAD L + +    F   ++ G  I  S+ RS
Sbjct  15   KLGAFVPFITIGDPDPTTFIHIIDTLIQSGADALELGI---PFSDPVSDGPSIQKSMERS  71

Query  60   VPRPGDASNTEKKPT------AFFDCHMMVE-------NPEKWVDDFAKCGADQFTFHYE  106
                 + S+  +               +++          + +    +    D       
Sbjct  72   FKSGANISSCLQLIKKIRNKYPTLPIGLLIYANLIFKNGIKNFYAHCSTLSIDSILIPDL  131

Query  107  ATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDM  166
              ++            I          S+D++ ++       + +    G  G    E  
Sbjct  132  PIEESSLFYNSAMYYQIAHIFICPTNASLDLIKKITDKGIGYIYLLSRSGITGINNTEFN  191

Query  167  MPKVET----LRAKFPHLNIQVDGGL-GKETIPKAAKAGANVIVAGTSVFT-AADPHDVI  220
              K+ T    ++     L I    G+   E    +  +G + I++G+ +     + H  I
Sbjct  192  KIKLNTLIYNIKQCNQKLPILQGFGIYSSEQARSSLLSGTSGIISGSCIANIIEENHPNI  251

Query  221  SFMKEEVSK  229
              + E++ K
Sbjct  252  DLLLEKIRK  260


>gi|12230290|sp|Q9L6N1|METE_SALTY  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=754

 Score =  112 bits (280),  Expect = 1e-24, Method: Composition-based stats.
 Identities = 33/205 (16%), Positives = 61/205 (29%), Gaps = 35/205 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              L  E   +  AG   + ID       P +  G P+      +           +    
Sbjct  579  LALRDEVADLEAAGIGIIQID------EPALREGLPLRRSDWDAYLEWGVEAFRINAAVA  632

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K       HM        +D  A   AD  T   E ++  + L++  ++           
Sbjct  633  KDETQIHTHMCYCEFNDIMDSIAALDADVITI--ETSRSDMELLESFEAFD---------  681

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +    V +V          E +   ++    + P   L +  D GL 
Sbjct  682  --YPNEIGPGVYDIHSPNVPSV----------EWIEALLKKAAQRIPAQRLWVNPDCGLK  729

Query  190  KETIPKAAKAGANVIVAGTSVFTAA  214
                P+   A AN++ A  ++  A 
Sbjct  730  TRGWPETRAALANMVKAAHNLRQAK  754


>gi|30173061|sp|Q8FBM1|METE_ECOL6  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=753

 Score =  111 bits (279),  Expect = 2e-24, Method: Composition-based stats.
 Identities = 32/198 (16%), Positives = 58/198 (29%), Gaps = 35/198 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              L  E   +  AG   + ID       P +  G P+      +  +        +    
Sbjct  579  LALRDEVADLEAAGIGIIQID------EPALREGLPLRRSDWDAYLQWGVEAFRINAAVA  632

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K       HM        +D  A   AD  T   E ++  + L++  +            
Sbjct  633  KDDTQIHTHMCYCEFNDIMDSIAALDADVITI--ETSRSDMELLESFEEFD---------  681

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +    V +V          E +   ++    + P   L +  D GL 
Sbjct  682  --YPNEIGPGVYDIHSPNVPSV----------EWIEALLKKAAKRIPAERLWVNPDCGLK  729

Query  190  KETIPKAAKAGANVIVAG  207
                P+   A AN++ A 
Sbjct  730  TRGWPETRAALANMVQAA  747


>gi|2851502|sp|P25665|METE_ECOLI  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=753

 Score =  111 bits (279),  Expect = 2e-24, Method: Composition-based stats.
 Identities = 32/198 (16%), Positives = 58/198 (29%), Gaps = 35/198 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              L  E   +  AG   + ID       P +  G P+      +  +        +    
Sbjct  579  LALRDEVADLEAAGIGIIQID------EPALREGLPLRRSDWDAYLQWGVEAFRINAAVA  632

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K       HM        +D  A   AD  T   E ++  + L++  +            
Sbjct  633  KDDTQIHTHMCYCEFNDIMDSIAALDADVITI--ETSRSDMELLESFEEFD---------  681

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +    V +V          E +   ++    + P   L +  D GL 
Sbjct  682  --YPNEIGPGVYDIHSPNVPSV----------EWIEALLKKAAKRIPAERLWVNPDCGLK  729

Query  190  KETIPKAAKAGANVIVAG  207
                P+   A AN++ A 
Sbjct  730  TRGWPETRAALANMVQAA  747


>gi|73622048|sp|Q82A81|TRPA_STRAW  Tryptophan synthase alpha chain
Length=277

 Score =  111 bits (279),  Expect = 2e-24, Method: Composition-based stats.
 Identities = 32/235 (13%), Positives = 74/235 (31%), Gaps = 23/235 (9%)

Query  21   ECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKPTAFFD--  78
                V + GAD + + +        +  G  I T+   ++      ++  +      +  
Sbjct  46   AIKAVFDGGADVVEVGL---PHSDPVLDGPVIQTADDIALRGGVRIADVMRTVREAHEAT  102

Query  79   ----CHMMVENP------EKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACA  128
                  M   NP      E++  + A+ G           Q+     +  +  G+     
Sbjct  103  GKPVLVMTYWNPIDRYGVERFTAELAEAGGAGCILPDLPVQESALWREHAEKHGLATVFV  162

Query  129  IKPGTSVDVLFEL-APHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGG  187
            + P +    L E+ A         ++    G +  + +    +         L + V  G
Sbjct  163  VAPSSKDARLAEITAAGSGFVYAASLMGVTGTRASVGEQAQDLVRRTRATTDLPVCVGLG  222

Query  188  LGKETIPKAAKAGANVIVAGTSVFT----AADPH---DVISFMKEEVSKELRSRD  235
            +   T        A+ ++ G++       A D     + +  +  E++K +R  D
Sbjct  223  VSNATQAAEVAGFADGVIVGSAFVKLMLDAEDEAAGLEAVRALAGELAKGVRGGD  277


>gi|73622011|sp|Q8FLJ5|TRPA_COREF  Tryptophan synthase alpha chain
Length=280

 Score =  111 bits (279),  Expect = 2e-24, Method: Composition-based stats.
 Identities = 29/206 (14%), Positives = 61/206 (29%), Gaps = 21/206 (10%)

Query  6    IAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
              P I+ +D    +        I AGAD L + V    F   +  G  +  S  R++   
Sbjct  19   FVPFIMLNDPSPEDSFQIISTAIEAGADALELGV---PFSDPVADGPTVAESHLRALDGG  75

Query  64   GDASNTEKKPT------AFFDCHMMVEN-------PEKWVDDFAKCGADQFTFHYEATQD  110
                +                  M++          +K+  +FA+ GAD         ++
Sbjct  76   STVDSCLALIARVREAYPEIPIGMLIYGNVPFTRGLDKFYREFAEAGADSILLPDVPVRE  135

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFEL-APHLDMALVMTVE--PGFGGQKFMEDMM  167
                ++  +  GI          S   L  + A        ++ +   G   +     + 
Sbjct  136  GAPFIQAAEGAGIDPIFIAPAQASETTLEGVSAASKGYIYAISRDGVTGTERESSTTGLT  195

Query  168  PKVETLRAKFPHLNIQVDGGLGKETI  193
              V+ ++       +   G    + +
Sbjct  196  DVVDNIKRFGGAPILLGFGISSPKHV  221


>gi|51316235|sp|Q6N765|METE_RHOPA  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=788

 Score =  111 bits (277),  Expect = 3e-24, Method: Composition-based stats.
 Identities = 30/201 (14%), Positives = 56/201 (27%), Gaps = 35/201 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              +  E   +  AGA  + ID         +  G P+  S                ++  
Sbjct  611  LAIRDEVGDLEQAGATMIQID------EAALREGLPLRRSEWKGYLDWAVECFRLCSSGV  664

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K       HM        +D  A   AD  +   E ++  + L+   K+           
Sbjct  665  KDETQIHTHMCYSEFNDIIDAIAAMDADVISI--ETSRSKMELLDAFKTYK---------  713

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPH--LNIQVDGGLG  189
                + +      +    V +VE               ++  R +     L +  D GL 
Sbjct  714  --YPNEIGPGVYDIHSPRVPSVEEMTT----------LLQLARQRLSDGQLWVNPDCGLK  761

Query  190  KETIPKAAKAGANVIVAGTSV  210
                 +   A  N++ A   +
Sbjct  762  TRGWDEVQGALVNMVEAARQI  782


>gi|54039757|sp|P66981|TRPA_MYCBO  Tryptophan synthase alpha chain
 gi|54042261|sp|P66980|TRPA_MYCTU  Tryptophan synthase alpha chain
Length=270

 Score =  110 bits (276),  Expect = 3e-24, Method: Composition-based stats.
 Identities = 28/233 (12%), Positives = 67/233 (28%), Gaps = 18/233 (7%)

Query  14   DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKP  73
            D          ++ +G D + + V    +      G  I  +   ++       +T    
Sbjct  37   DVPASVAAMTALVESGCDIIEVGV---PYSDPGMDGPTIARATEAALRGGVRVRDTLAAV  93

Query  74   TAF-----FDCHMMVENP------EKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKG  122
             A          M   NP      + +  D A  G            +    +   +   
Sbjct  94   EAISIAGGRAVVMTYWNPVLRYGVDAFARDLAAAGGLGLITPDLIPDEAQQWLAASEEHR  153

Query  123  IKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFM--EDMMPKVETLRAKFPHL  180
            +     + P ++ + L          +      G  G +    +     V  ++A    +
Sbjct  154  LDRIFLVAPSSTPERLAATVEASRGFVYAASTMGVTGARDAVSQAAPELVGRVKA-VSDI  212

Query  181  NIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHD-VISFMKEEVSKELR  232
             + V  G+            A+ ++ G+++ TA       +  +  E++  +R
Sbjct  213  PVGVGLGVRSRAQAAQIAQYADGVIVGSALVTALTEGLPRLRALTGELAAGVR  265


>gi|31340219|sp|Q87NA1|METE_VIBPA  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=760

 Score =  109 bits (274),  Expect = 7e-24, Method: Composition-based stats.
 Identities = 36/217 (16%), Positives = 63/217 (29%), Gaps = 44/217 (20%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              L  E   + +AG + + ID       P I  G P+      +           S    
Sbjct  584  LALRDEVSDLQDAGINIIQID------EPAIREGLPLKKRDHKAYLEWAVNAFKISAASA  637

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            KP      HM      + +D  A   AD  T   E ++  + L+K  +            
Sbjct  638  KPETQIHTHMCYSEFNEIIDSVAALDADVITI--ETSRSNMELLKAFEEFN---------  686

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKE  191
                + +      +    + T E   G  K   + +P           L +  D GL   
Sbjct  687  --YPNEIGPGVYDIHSPNIPTEEWIEGLIKKAAEKIP--------VQRLWVNPDCGLKTR  736

Query  192  TIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVS  228
               +   A AN++                  ++ E++
Sbjct  737  NWAETEAALANLV-------------SAAKKLRAELA  760


>gi|30173084|sp|Q8KRG6|METE_VIBHA  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=760

 Score =  109 bits (273),  Expect = 7e-24, Method: Composition-based stats.
 Identities = 33/218 (15%), Positives = 62/218 (28%), Gaps = 48/218 (22%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              L  E   +  AG + + ID       P I  G P+      +  +        +    
Sbjct  584  LALRDEVSDLQQAGINIIQID------EPAIREGLPLKKRDHKAYLQWAVDAFKIAAASA  637

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            KP      HM      + +D  A   AD  T   E ++  + L+K  +            
Sbjct  638  KPETQIHTHMCYSEFNEIIDSVAALDADVITI--ETSRSNMELLKAFEDFN---------  686

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +    + +           E +   ++    K P   L +  D GL 
Sbjct  687  --YPNEIGPGVYDIHSPNIPS----------EEWIEELIKKAAEKIPAQRLWVNPDCGLK  734

Query  190  KETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEV  227
                 +   A AN++                  ++ E+
Sbjct  735  TRNWSETEAALANLV-------------SAAKKLRAEL  759


>gi|12230284|sp|Q9KRD8|METE_VIBCH  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=761

 Score =  109 bits (272),  Expect = 1e-23, Method: Composition-based stats.
 Identities = 34/201 (16%), Positives = 61/201 (30%), Gaps = 35/201 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              L  E   + +AG + + ID       P I  G P+             +    S    
Sbjct  584  LALRDEVADLQDAGINIIQID------EPAIREGLPLKKRDHQTYLDWAVQAFKISAGSA  637

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            +P      HM      + ++  A   AD  T   E ++  + L+K  +            
Sbjct  638  RPETQIHTHMCYSEFNEIIESVAALDADVITI--ETSRSNMELLKAFEEFN---------  686

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +         P    Q ++E     +     K P   L +  D GL 
Sbjct  687  --YPNEIGPGVYDIH-------SPNIPAQAWIE---DLLRKAAEKIPAQRLWVNPDCGLK  734

Query  190  KETIPKAAKAGANVIVAGTSV  210
                P+   A  N++ A  ++
Sbjct  735  TRNWPEVEAALTNMVNAAKAL  755


>gi|51316440|sp|Q87XJ9|METE_PSESM  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=766

 Score =  109 bits (272),  Expect = 1e-23, Method: Composition-based stats.
 Identities = 26/199 (13%), Positives = 51/199 (25%), Gaps = 35/199 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              +  E   +  AG   + ID            G P+  +                 +  
Sbjct  593  LAIRDEVLDLERAGIKIVQID------EAAFREGLPLRKAQWQQYLDWAVAAFRLCASGV  646

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            +       HM        +   A   AD  T   E ++  + L+   ++           
Sbjct  647  RDETQIHTHMCYSEFNDVIKSIAAMDADVITI--ETSRSDMELLDAFEAFD---------  695

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +    V              +M+  +     + P   L +  D GL 
Sbjct  696  --YPNDIGPGVYDIHSPRVP----------ETAEMVSLIAKAARRIPAERLWVNPDCGLK  743

Query  190  KETIPKAAKAGANVIVAGT  208
                P+   A  N++ A  
Sbjct  744  TRGWPETEAALINMVAAAR  762


>gi|30173122|sp|Q9F187|METE_RALEU  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=792

 Score =  108 bits (270),  Expect = 2e-23, Method: Composition-based stats.
 Identities = 29/199 (14%), Positives = 58/199 (29%), Gaps = 31/199 (15%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              +  E   +  AG   + ID       P +  G P+  +               S +  
Sbjct  580  LAIRDEVCDLEQAGIRVIQID------EPALREGLPLRRADWDAYLDWAVTAFRLSASGV  633

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            +       HM        +   A   AD  T   E ++  + L++               
Sbjct  634  QDQTQIHTHMCYAEFNDILPAIAAMDADVITI--ETSRSAMELLE-----------GFGD  680

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKE  191
                + +      +    V +V+     ++ ++     V   R     L +  D GL   
Sbjct  681  FDYPNEIGPGVYDIHSPRVPSVQA---MERLLDRACEVVPPQR-----LWVNPDCGLKTR  732

Query  192  TIPKAAKAGANVIVAGTSV  210
               +   A AN++ A  ++
Sbjct  733  GWEETEAALANMVSAARAL  751


>gi|51316403|sp|Q82UP6|METE_NITEU  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=758

 Score =  108 bits (269),  Expect = 2e-23, Method: Composition-based stats.
 Identities = 28/204 (13%), Positives = 56/204 (27%), Gaps = 35/204 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              +  E   + NAG   + ID       P    G P+      S      +    +++  
Sbjct  581  LAIRDEVADLENAGIGMIQID------EPAFREGLPLRKQDWKSYLDWAVKAFRVASSGV  634

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K       HM        +   A+  AD  T   E ++  + L+                
Sbjct  635  KDETQIHTHMCYSEFHDILPAIAELDADVITI--ETSRSRMELLDAFVKF----------  682

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
             +  + +      +    V              +M   ++          L +  D GL 
Sbjct  683  -SYPNEIGPGVYDIHSPRVPD----------ASEMFELLKKASRYIDPTLLWVNPDCGLK  731

Query  190  KETIPKAAKAGANVIVAGTSVFTA  213
                P+   A   ++    ++ +A
Sbjct  732  TRNWPETQTALQKMVDCAKTLRSA  755


>gi|6226272|sp|O68816|TRPA_STRCO  Tryptophan synthase alpha chain
Length=271

 Score =  107 bits (268),  Expect = 3e-23, Method: Composition-based stats.
 Identities = 27/236 (11%), Positives = 70/236 (29%), Gaps = 23/236 (9%)

Query  20   CECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKPTAFFD-  78
                  ++ GAD + + +        +  G  I T+   ++      ++  +      + 
Sbjct  39   EAVKAALDGGADVVEVGL---PHSDPVLDGPVIQTADDIALRGGVRIADVMRTVREAHEA  95

Query  79   -----CHMMVENP------EKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAAC  127
                   M   NP      E++  + A+ G           Q+     +     G+    
Sbjct  96   TGKPILVMTYWNPIDRYGVERFTAELAEAGGAGCILPDLPVQESALWREHADKHGLATVF  155

Query  128  AIKPGTSVDVLFEL-APHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDG  186
             + P +    L E+ A         ++    G +  +      +           + V  
Sbjct  156  VVAPSSRDARLAEITAVGSGFVYAASLMGVTGTRASVGAQAEDLVRRTRATTDTPVCVGL  215

Query  187  GLGKETIPKAAKAGANVIVAGTSVFT----AADPH---DVISFMKEEVSKELRSRD  235
            G+            A+ ++ G++       A D     + +  +  +++K +R + 
Sbjct  216  GVSNAAQAAEVAGFADGVIVGSAFVKRMLDAPDDAAGLEGVRALAADLAKGVRGQA  271


>gi|22261818|sp|P06562|TRPA_CORGL  Tryptophan synthase alpha chain
Length=280

 Score =  107 bits (267),  Expect = 4e-23, Method: Composition-based stats.
 Identities = 34/225 (15%), Positives = 71/225 (31%), Gaps = 21/225 (9%)

Query  6    IAPSILASDF--ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRP  63
              P I+ SD             I AGAD L + V    F   +  G  +  S  R++   
Sbjct  19   FVPFIMLSDPSPEEAFQIISTAIEAGADALELGV---PFSDPVADGPTVAESHLRALDGG  75

Query  64   GDASNTEKKPT------AFFDCHMMVEN-------PEKWVDDFAKCGADQFTFHYEATQD  110
                +  ++              M++          +++  +FA+ GAD         ++
Sbjct  76   ATVDSALEQIKRVRAAYPEVPIGMLIYGNVPFTRGLDRFYQEFAEAGADSILLPDVPVRE  135

Query  111  PLHLVKLIKSKGIKAACAIKPGTSVDVLFEL-APHLDMALVMTVE--PGFGGQKFMEDMM  167
                     + GI          S   L  + A        ++ +   G   +   + + 
Sbjct  136  GAPFSAAAAAAGIDPIYIAPANASEKTLEGVSAASKGYIYAISRDGVTGTERESSTDGLS  195

Query  168  PKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
              V+ ++       +   G    + +  A  AGA+  + G+++  
Sbjct  196  AVVDNIKKFDGAPILLGFGISSPQHVADAIAAGASGAITGSAITK  240


>gi|51316225|sp|Q6LSD6|METE_PHOPR  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=766

 Score =  107 bits (267),  Expect = 5e-23, Method: Composition-based stats.
 Identities = 31/218 (14%), Positives = 60/218 (27%), Gaps = 44/218 (20%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              L  E   +  AG   + ID       P I  G P+      +           S    
Sbjct  586  LALRDEVSDLQAAGIKIIQID------EPAIREGLPLKESQWQAYLDWAVNAFKISAASA  639

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            +P      HM        +   A   AD  T   E ++  + L+K  +            
Sbjct  640  EPQTQIHTHMCYSEFNHIIKSVAALDADVITI--ETSRSDMELLKAFEEFD---------  688

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKE  191
                + +      +    + ++E      +  E ++P           L I  D GL   
Sbjct  689  --YPNEIGPGVYDIHSPNIPSIEQIVHLVEKAETLIP--------IERLWINPDCGLKTR  738

Query  192  TIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSK  229
               +   A  +++             +    ++E+  +
Sbjct  739  NWEETEAALRSMV-------------EATKKLREQWQE  763


>gi|31076767|sp|Q89B24|METE_BUCBP  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=756

 Score =  106 bits (265),  Expect = 6e-23, Method: Composition-based stats.
 Identities = 28/233 (12%), Positives = 61/233 (26%), Gaps = 52/233 (22%)

Query  1    MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIV----TSL  56
            + K II+  I       L  E   +  +G   + ID       P +  G P+        
Sbjct  570  LSKKIISRQIA----LALRDEVLDLEQSGVKIIQID------EPALREGLPLRLSLRNEY  619

Query  57   RRSVPRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVK  116
                      S++          HM        ++      AD  T   E ++  + L++
Sbjct  620  LSWAVDSFKLSSSGVCDETQIHTHMCYCEFNDIMNAIVLLDADVITI--ETSRSDMELLE  677

Query  117  LIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAK  176
              K                + +      +    + ++E               +      
Sbjct  678  FFKEFK-----------YPNDIGPGVYDIHSPNIPSIEWIMT----------LLRQAMHY  716

Query  177  FPH--LNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEV  227
             P   L +  D GL   T  +               ++  +       +++++
Sbjct  717  IPVKRLWVNPDCGLKTRTWDET-------------YYSLENMVRAAKILRKKL  756


>gi|8134568|sp|P93263|METE_MESCR  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Vitamin-B12-independent methionine synthase isozyme) 
(Cobalamin-independent methionine synthase isozyme)
Length=765

 Score =  106 bits (264),  Expect = 9e-23, Method: Composition-based stats.
 Identities = 31/219 (14%), Positives = 62/219 (28%), Gaps = 43/219 (19%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              +  E   +  AG + + ID         +  G P+  S      +        +N   
Sbjct  585  LAIKNEVEDLEKAGINVIQID------EAALREGLPLRKSEHDFYLKWAVHSFRITNVGV  638

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            + T     HM   N    +       AD  T   E ++    L+ + +  G+K    I P
Sbjct  639  QDTTQIHTHMCYSNFNDIIHSIIDMDADVITI--ENSRSDEKLLSVFRE-GVKYGAGIGP  695

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKE  191
                         +    +   E      + M  ++            L +  D GL   
Sbjct  696  ---------GVYDIHSPRIPPTEELADRIRKMLAVLES--------NVLWVNPDCGLKTR  738

Query  192  TIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKE  230
               +   A +N++                  +++E++  
Sbjct  739  KYGEVNPALSNMVA-------------AAKQLRQELASA  764


>gi|30173017|sp|Q8CWK1|METE_VIBVU  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=778

 Score =  106 bits (264),  Expect = 9e-23, Method: Composition-based stats.
 Identities = 34/220 (15%), Positives = 62/220 (28%), Gaps = 36/220 (16%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              L  E   + +AG + + ID       P I  G P+                  S    
Sbjct  584  LALRDEVSDLQDAGINIIQID------EPAIREGLPLKKRDHQNYLDWAVEAFRISAASA  637

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            +P      HM      + ++  A   AD  T   E ++  + L+K  +            
Sbjct  638  RPETQIHTHMCYSEFNEIIESVAALDADVITI--ETSRSNMELLKAFEEFN---------  686

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKE  191
                + +      +    + + E      K     +P           L +  D GL   
Sbjct  687  --YPNEIGPGVYDIHSPNIPSEEWIVDLVKKAAQKIP--------VERLWVNPDCGLKTR  736

Query  192  TIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKEL  231
              P+   A AN++ A   +       +         S+ +
Sbjct  737  NWPETEAALANLVSAAKRL-----RKEFAKETTAVNSEAV  771


>gi|12230241|sp|P57703|METE_PSEAE  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=766

 Score =  106 bits (264),  Expect = 1e-22, Method: Composition-based stats.
 Identities = 26/203 (12%), Positives = 54/203 (26%), Gaps = 35/203 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              +  E   +  AG   + ID            G P+                    +  
Sbjct  588  LAIRDEVVDLEAAGIRIVQID------EAAFREGLPLRRNAWPHYLEWATEAFRLCASGV  641

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            +       HM        ++  A   AD  T   E ++  + L++  +            
Sbjct  642  RDETQIHTHMCYSEFNDVIESIAAMDADVITI--ETSRSDMELLEAFEQFD---------  690

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +    V +           E+++  +     + P   L +  D GL 
Sbjct  691  --YPNEIGPGVYDIHSPRVPSR----------EEIVALLRKAARRIPAERLWVNPDCGLK  738

Query  190  KETIPKAAKAGANVIVAGTSVFT  212
                P+   A  N++ A   +  
Sbjct  739  TRAWPETEAALVNMVAAARELRG  761


>gi|51316369|sp|Q7VVU3|METE_BORPE  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=764

 Score =  106 bits (264),  Expect = 1e-22, Method: Composition-based stats.
 Identities = 32/202 (15%), Positives = 55/202 (27%), Gaps = 31/202 (15%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              L  E   +  AG   + ID       P I  G P+  +               S    
Sbjct  590  LALRDEVVDLEAAGIRVIQID------EPAIREGLPLRRADWRAYLDWAVDCFRLSTAGV  643

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
                    HM        ++  A   AD  T   E ++  + L+K  +            
Sbjct  644  GEATQIHTHMCYSEFNDIIESIAAMDADVITI--ETSRSNMELLKAFEDF----------  691

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKE  191
                + +      +    V  V+      +     +PK          L +  D GL   
Sbjct  692  -HYPNDIGPGVYDIHSPNVPEVDWMVELMRKAAARLPK--------ERLWVNPDCGLKTR  742

Query  192  TIPKAAKAGANVIVAGTSVFTA  213
              P+   A   ++ A  ++  A
Sbjct  743  AWPETEAALIGMVQAARTLRAA  764


>gi|51316375|sp|Q7W791|METE_BORPA  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
 gi|51316377|sp|Q7WKM7|METE_BORBR  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=764

 Score =  105 bits (263),  Expect = 1e-22, Method: Composition-based stats.
 Identities = 32/202 (15%), Positives = 55/202 (27%), Gaps = 31/202 (15%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              L  E   +  AG   + ID       P I  G P+  +               S    
Sbjct  590  LALRDEVVDLEAAGIRVIQID------EPAIREGLPLRRADWRAYLDWAVDCFRLSTAGV  643

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
                    HM        ++  A   AD  T   E ++  + L+K  +            
Sbjct  644  GEATQIHTHMCYSEFNDIIESIAAMDADVITI--ETSRSNMELLKAFEDF----------  691

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKE  191
                + +      +    V  V+      +     +PK          L +  D GL   
Sbjct  692  -HYPNDIGPGVYDIHSPNVPEVDWMVELMRKAAARLPK--------ERLWVNPDCGLKTR  742

Query  192  TIPKAAKAGANVIVAGTSVFTA  213
              P+   A   ++ A  ++  A
Sbjct  743  AWPETEAALIGMVQAARTLRAA  764


>gi|73622023|sp|Q7VGA8|TRPA_HELHP  Tryptophan synthase alpha chain
Length=267

 Score =  105 bits (262),  Expect = 1e-22, Method: Composition-based stats.
 Identities = 39/232 (16%), Positives = 73/232 (31%), Gaps = 26/232 (11%)

Query  3    KPIIAPSILAS--DFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSV  60
            KP +   I+A    F +       +  AGA +L +      F      G+ I  +  +S+
Sbjct  6    KPQLMGHIIAGYPSFESSLYAALGICQAGASYLEV---QFPFSDPNADGRVIEEACNKSI  62

Query  61   PRPGDASNTEKK------------PTAFFDCHMMV------ENPEKWVDDFAKCGADQFT  102
             +    +   K                     M           E ++ +  KCG     
Sbjct  63   AQGFKVAQGFKLLHTLSQHINQDNKQPTRLIIMTYANLIFHYGIEAFIKEAKKCGVWGII  122

Query  103  FHYEATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKF  162
                  +    L  L K   I+    I P  S+  + ++A   D  + +    G  G+K 
Sbjct  123  APDLPIESDESLRILAKKHHIRIISLIAPKVSISRIKKIAKISDEIVYVVARAGITGEKT  182

Query  163  M--EDMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFT  212
               + +   +  ++       I +  G+       A K   ++IVAG+    
Sbjct  183  HIDKALFEWIRLIQKHCKK-PIALGFGINSYEQVAALKDKVDIIVAGSYFVR  233


>gi|8134569|sp|Q42662|METE_SOLSC  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Vitamin-B12-independent methionine synthase isozyme) 
(Cobalamin-independent methionine synthase isozyme)
Length=764

 Score =  105 bits (262),  Expect = 1e-22, Method: Composition-based stats.
 Identities = 31/196 (15%), Positives = 54/196 (27%), Gaps = 30/196 (15%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              +  E   +  AG   + ID         +  G P+  S               +N   
Sbjct  584  LAIKDEVEDLEKAGITVIQID------EAALREGLPLRKSEHAFYLDWAVHSFRITNVGV  637

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            + T     HM   N    +       AD  T   E ++    L+ + +  G+K    I P
Sbjct  638  QDTTQIHTHMCYSNFNDIIHSIINMDADVITI--ENSRSDEKLLSVFRE-GVKYGAGIGP  694

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKE  191
                         +    + + E        M  ++            L +  D GL   
Sbjct  695  ---------GVYDIHSPRIPSTEEIADRINKMLAVLE--------TNILWVNPDCGLKTR  737

Query  192  TIPKAAKAGANVIVAG  207
               +   A  N++ A 
Sbjct  738  KYAEVKPALENMVAAA  753


>gi|51316409|sp|Q83A62|METE_COXBU  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=775

 Score =  105 bits (262),  Expect = 2e-22, Method: Composition-based stats.
 Identities = 26/202 (12%), Positives = 56/202 (27%), Gaps = 31/202 (15%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              L  E   +  +G   + ID       P      P+  +          +    ++   
Sbjct  583  LALRDEVQDLERSGVRVIQID------EPAFRECLPLRKAAWQDYLEWAVKCFRLASCGV  636

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K       HM        ++  A   AD  T   E+++  + ++K  +            
Sbjct  637  KDETQIHTHMCYSEFNDIIEAIAALDADVITI--ESSRSEMEILKSFEKF----------  684

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKE  191
                + +      +         P       +E++  +          L I  D GL   
Sbjct  685  -AYPNDIGPGIYDIH-------SPRIPRVAEIEELAVRALQYI-PIERLWINPDCGLKTR  735

Query  192  TIPKAAKAGANVIVAGTSVFTA  213
               +  +A + ++ A   +  A
Sbjct  736  NWEETKEALSRMVDAAKHLRKA  757


>gi|30173110|sp|Q98A73|METE_RHILO  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=776

 Score =  104 bits (259),  Expect = 4e-22, Method: Composition-based stats.
 Identities = 30/205 (14%), Positives = 58/205 (28%), Gaps = 35/205 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              +  E   +  AGA  + ID         +  G P+  +               ++T  
Sbjct  598  LAIRDEVSDLEKAGAKMIQID------EAALREGLPLREADWQAYLDWAVECFRLASTAV  651

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
                    HM        VD  A   AD  +   E ++  L L+  +++           
Sbjct  652  GDATQIHTHMCYSEFGDIVDAIAAMDADVISI--ETSRSQLELLDTLRTFK---------  700

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPH--LNIQVDGGLG  189
                + +      +    V  V           ++   +   R +     L +  D GL 
Sbjct  701  --YPNEIGPGVYDIHSPRVPEVG----------EISNLIMLARKRLSDGQLWVNPDCGLK  748

Query  190  KETIPKAAKAGANVIVAGTSVFTAA  214
                 +   A  N++ A  ++   A
Sbjct  749  TRRWEEVRPALVNMVAAARAIRQKA  773


>gi|51316309|sp|Q7MJM6|METE_VIBVY  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=778

 Score =  104 bits (259),  Expect = 4e-22, Method: Composition-based stats.
 Identities = 35/220 (15%), Positives = 61/220 (27%), Gaps = 36/220 (16%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              L  E   + +AG + + ID       P I  G P+                  S    
Sbjct  584  LALRDEVSDLQDAGINIIQID------EPAIREGLPLKKRDHQNYLDWALEAFRISAASA  637

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            +P      HM      + ++  A   AD  T   E ++  + L+K  +            
Sbjct  638  RPETQIHTHMCYSEFNEIIESVAALDADVITI--ETSRSNMELLKAFEEFN---------  686

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKE  191
                + +      +    + + E      K     +P           L +  D GL   
Sbjct  687  --YPNEIGPGVYDIHSPNIPSEEWIVDLVKKAAQKIP--------VERLWVNPDCGLKTR  736

Query  192  TIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKEL  231
              P+   A AN++ A   +       +         S  L
Sbjct  737  NWPETEAALANLVSAAKRL-----RKEFAKETTAVNSDAL  771


>gi|38258049|sp|Q88X63|METE_LACPL  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=768

 Score =  102 bits (254),  Expect = 1e-21, Method: Composition-based stats.
 Identities = 26/201 (12%), Positives = 53/201 (26%), Gaps = 35/201 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              L  E   +  AG   + +D       P +  G P+      +           + T  
Sbjct  588  LALRQEVQNLEKAGIKIIQVD------EPALREGLPLKQRHWQAYLDEAVYSFKITTTGV  641

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            +       HM   N    ++      AD  +   E ++    ++   +  G         
Sbjct  642  QNDTQIHTHMCYSNFADIINTIKALDADVISI--ETSRSHGEIISAFEQTGYD-------  692

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                  +      +    V +V           ++   ++            I  D GL 
Sbjct  693  ----QEIGLGVYDIHSPRVPSV----------AEIEANIQRALRVIDARQFWINPDCGLK  738

Query  190  KETIPKAAKAGANVIVAGTSV  210
                 +   A  N+I A  ++
Sbjct  739  TRQESETLAALKNMIAARNAI  759


>gi|11133452|sp|P57142|METE_BUCAI  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=758

 Score =  102 bits (254),  Expect = 2e-21, Method: Composition-based stats.
 Identities = 30/219 (13%), Positives = 62/219 (28%), Gaps = 48/219 (21%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              L  E   +     + + ID       P +  G P+  S               S +  
Sbjct  577  LALYDEVLDLEKEKIEIIQID------EPALREGLPLRKSSWHEYLSWAVDVFRLSASGV  630

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K T     HM        +D  A   AD  T   EA +  + L++  K            
Sbjct  631  KNTTQIHTHMCYCEFNDIMDSIALLDADVITI--EAARSDMELLESFKKFK---------  679

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +   A  +  + + +V          + ++  +       P   + +  D GL 
Sbjct  680  --YPNEVGPGAYDIHSSNIPSV----------QSIISLLNKAMKYIPLKRIWVNPDCGLK  727

Query  190  KETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVS  228
                 +   +  N++             +    ++E++ 
Sbjct  728  TRNWNETILSLKNMV-------------EATKILREKMK  753


>gi|8134570|sp|Q42699|METE_CATRO  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Vitamin-B12-independent methionine synthase isozyme) 
(Cobalamin-independent methionine synthase isozyme)
Length=765

 Score =  101 bits (252),  Expect = 2e-21, Method: Composition-based stats.
 Identities = 30/199 (15%), Positives = 56/199 (28%), Gaps = 30/199 (15%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              +  E   +  AG + + ID         +  G P+  +               +N   
Sbjct  585  LAIKDEVEDLEKAGINVIQID------EAALREGLPLRKAEHAFYLDWAVHSFRITNLPL  638

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            + T     HM   N    +       AD  T   E ++    L+ + +  G+K    I P
Sbjct  639  QDTTQIHTHMCYSNFNDIIHSIIDMDADVMTI--ENSRSSEKLLSVFRE-GVKYGAGIGP  695

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKE  191
                         +    + + E        M  ++            L +  D GL   
Sbjct  696  ---------GVYDIHSPRIPSTEEIADRINKMLAVLD--------TNILWVNPDCGLKTR  738

Query  192  TIPKAAKAGANVIVAGTSV  210
               +   A  N++ A   +
Sbjct  739  KYAEVKPALENMVSAAKLI  757


>gi|12230297|sp|Q9PB72|METE_XYLFA  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=758

 Score =  101 bits (252),  Expect = 3e-21, Method: Composition-based stats.
 Identities = 29/195 (14%), Positives = 54/195 (27%), Gaps = 35/195 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              L  E   +  AG   + ID       P I  G P+                  +++  
Sbjct  584  LALRDEVQDLEKAGIKVIQID------EPAIREGLPLRRGEWADYLNWAVESFRIASSNV  637

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            + T     HM        ++  A   AD  +   E ++  + L+                
Sbjct  638  RDTTQIHTHMCYSEFNDIIEAVAALDADVISI--ETSRSRMELLDAFVKFR---------  686

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +    V             E+M+  ++  RA  P   L +  D GL 
Sbjct  687  --YPNAIGPGVYDIHSPRVP----------QEEEMVLLLKKARAVLPPEQLWVNPDCGLK  734

Query  190  KETIPKAAKAGANVI  204
                 +   A   ++
Sbjct  735  TRGWKETRAALQTMV  749


>gi|119370764|sp|Q49VB7|HPS3_STAS1  3-hexulose-6-phosphate synthase 3 (HPS 3) (D-arabino-3-hexulose-6-phosphate 
formaldehyde lyase 3)
Length=210

 Score =  101 bits (251),  Expect = 3e-21, Method: Composition-based stats.
 Identities = 45/221 (20%), Positives = 80/221 (36%), Gaps = 20/221 (9%)

Query  11   LASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTE  70
            LA D  N   E  ++ N   D          +V  + +G PIV  +   +P     ++  
Sbjct  5    LAIDLLN-KEEAAELANKVKD----------YVDIVEIGTPIV--INEGLPAVQYLNDNI  51

Query  71   KKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQ-DPLHLVKLIKSKGIKAACAI  129
                   D  +M +  +  V    K GAD  T    A        V+     G +    +
Sbjct  52   DGVKVLADLKIM-DAADYEVSQAVKFGADVVTILGVAEDASIKGAVEEAHKNGKE---LL  107

Query  130  KPGTSVDVLFELAPHLD--MALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGG  187
                +V  L + A  LD   A  + V  G+  Q   E  +  +  +++   +  + V GG
Sbjct  108  VDMIAVQDLQKRAKELDELGADYIAVHTGYDLQAEGESPLESLRQVKSVINNSKVAVIGG  167

Query  188  LGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVS  228
            +  +TI +      +++V G  +  A DP       K+ + 
Sbjct  168  IKPDTIKEVVAEEPDLVVVGGGIANADDPVAAAKACKDAIE  208


>gi|3334472|sp|P80877|METE_BACSU  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase) (Superoxide-inducible 
protein 9) (SOI9)
Length=762

 Score =  101 bits (251),  Expect = 3e-21, Method: Composition-based stats.
 Identities = 29/196 (14%), Positives = 51/196 (26%), Gaps = 31/196 (15%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIV----TSLRRSVPRPGDASNTEK  71
              L  E   + +AG   + +D       P +  G P+                  + +  
Sbjct  583  LALRKEVKALEDAGIQIIQVD------EPALREGLPLKTRDWDEYLTWAAEAFRLTTSSV  636

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K       HM   N E  VD      AD  T   E ++     +  +K+        +  
Sbjct  637  KNETQIHTHMCYSNFEDIVDTINDLDADVITI--EHSRSHGGFLDYLKNHPYLKGLGL--  692

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKE  191
                         +    V + E  +        + P             +  D GL   
Sbjct  693  ---------GVYDIHSPRVPSTEEMYNIIVDALAVCP--------TDRFWVNPDCGLKTR  735

Query  192  TIPKAAKAGANVIVAG  207
               +   A  N++ A 
Sbjct  736  QQEETVAALKNMVEAA  751


>gi|119370762|sp|Q49WT7|HPS1_STAS1  3-hexulose-6-phosphate synthase 1 (HPS 1) (D-arabino-3-hexulose-6-phosphate 
formaldehyde lyase 1)
Length=210

 Score =  100 bits (250),  Expect = 4e-21, Method: Composition-based stats.
 Identities = 43/221 (19%), Positives = 79/221 (35%), Gaps = 20/221 (9%)

Query  11   LASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTE  70
            LA D  N   E   + N   D+++I          + +G PIV  +   +P     ++  
Sbjct  5    LAIDLLN-KEEATILANKVKDYINI----------VEIGTPIV--INEGLPAVQHLNDNI  51

Query  71   KKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQ-DPLHLVKLIKSKGIKAACAI  129
                   D  +M +  +  V    K GAD  T    A        V      G +    +
Sbjct  52   DGVKVLADLKIM-DAADYEVSQAVKFGADIVTILGVAEDASIKAAVDEAHKHGKQ---LL  107

Query  130  KPGTSVDVLFELAPHLD--MALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGG  187
                +V  L + A  LD   A  + V  G+  Q   +  +  +  +++   +  + V GG
Sbjct  108  VDMIAVQDLEKRAKDLDDLGADYIAVHTGYDLQAEGQSPLESLRKVKSVISNSKVAVAGG  167

Query  188  LGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVS  228
            +  +TI        ++I+ G  +  A DP +     +  + 
Sbjct  168  IKPDTIKDIVAENPDLIIVGGGIANADDPVEAAKQCRAAIE  208


>gi|32129722|sp|Q87BY8|METE_XYLFT  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=758

 Score =  100 bits (249),  Expect = 5e-21, Method: Composition-based stats.
 Identities = 29/195 (14%), Positives = 53/195 (27%), Gaps = 35/195 (17%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVT----SLRRSVPRPGDASNTEK  71
              L  E   +  AG   + ID       P I  G P+                  +++  
Sbjct  584  LALRDEVQDLEKAGIKVIQID------EPAIREGLPLRRGEWADYLNWAVESFRIASSNV  637

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
              T     HM        ++  A   AD  +   E ++  + L+                
Sbjct  638  HDTTQIHTHMCYSEFNDIIEAVAALDADVISI--ETSRSRMELLDAFVKFR---------  686

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFP--HLNIQVDGGLG  189
                + +      +    V             E+M+  ++  RA  P   L +  D GL 
Sbjct  687  --YPNAIGPGVYDIHSPRVP----------QEEEMVLLLKKARAVLPPEQLWVNPDCGLK  734

Query  190  KETIPKAAKAGANVI  204
                 +   A   ++
Sbjct  735  TRGWKETRAALQTMV  749


>gi|119370763|sp|Q49WT0|HPS2_STAS1  3-hexulose-6-phosphate synthase 2 (HPS 2) (D-arabino-3-hexulose-6-phosphate 
formaldehyde lyase 2)
Length=213

 Score =   99 bits (248),  Expect = 6e-21, Method: Composition-based stats.
 Identities = 43/226 (19%), Positives = 80/226 (35%), Gaps = 20/226 (8%)

Query  11   LASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTE  70
            LA D  N   +  ++ N   D           V  + +G PIV  +   +P     ++  
Sbjct  5    LAIDLLN-KEDAAELANKVKD----------HVDIVEIGTPIV--INEGLPAVQHLNDNV  51

Query  71   KKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQ-DPLHLVKLIKSKGIKAACAI  129
                   D  +M +  +  V    K GAD  T    A        V      G +    +
Sbjct  52   DGVKVLADLKIM-DAADYEVSQAVKFGADIVTILGVAEDASIKAAVDEAHKHGKQ---LL  107

Query  130  KPGTSVDVLFELAPHLD--MALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGG  187
                +V  L + A  LD   A  + V  G+  Q   +  +  +  +++   +  + V GG
Sbjct  108  VDMIAVQDLEKRAKDLDDLGADYIAVHTGYDLQAEGQSPLESLRKVKSVISNSKVAVAGG  167

Query  188  LGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRS  233
            +  +TI        ++I+ G  +  A DP +     ++ V    ++
Sbjct  168  IKPDTIKDIVAENPDLIIVGGGIANADDPVEAAKQCRDIVDAHTKA  213


>gi|25008739|sp|Q8KA71|METE_BUCAP  5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 
(Methionine synthase, vitamin-B12 independent isozyme) 
(Cobalamin-independent methionine synthase)
Length=757

 Score = 99.6 bits (247),  Expect = 9e-21, Method: Composition-based stats.
 Identities = 29/220 (13%), Positives = 57/220 (25%), Gaps = 48/220 (21%)

Query  16   ANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTS----LRRSVPRPGDASNTEK  71
              L  E   +     + + ID       P +  G P+  S               S++  
Sbjct  578  LALRDEVLDLEKEKIEIIQID------EPALREGLPLRKSLWNEYLSWAVDAFRLSSSGV  631

Query  72   KPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKP  131
            K T     HM        +   +   AD  T   E  +  + L+K  K+           
Sbjct  632  KNTTQIHTHMCYCEFHDIMHAISFLDADVITI--ETARSDMELLKSFKTFK---------  680

Query  132  GTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPH--LNIQVDGGLG  189
                + +      +                 +  +   +    A  P   + +  D GL 
Sbjct  681  --YPNEIGPGVYDIHS----------SNIPSITSIKFLLNKAIAYIPVERIWVNPDCGLK  728

Query  190  KETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSK  229
                 +   A  N++                  M++++ K
Sbjct  729  TRNWNETILALKNMVC-------------AAKEMRDKIKK  755


>gi|119370767|sp|Q2YS94|HPS_STAAB  3-hexulose-6-phosphate synthase (HPS) (D-arabino-3-hexulose-6-phosphate 
formaldehyde lyase)
Length=210

 Score = 98.8 bits (245),  Expect = 1e-20, Method: Composition-based stats.
 Identities = 39/221 (17%), Positives = 79/221 (35%), Gaps = 20/221 (9%)

Query  11   LASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTE  70
            LA D  N   +  ++ N   D          +V  + +G PI+      +P     ++  
Sbjct  5    LAIDLLN-KEDAAELANKVKD----------YVDIVEIGTPII--YNEGLPAVKHMADNI  51

Query  71   KKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQ-DPLHLVKLIKSKGIKAACAI  129
                   D  +M +  +  V    K GAD  T    A        ++       +    +
Sbjct  52   SNVKVLADMKIM-DAADYEVSQAIKFGADVITILGVAEDASIKTAIEEAHKNNKQ---LL  107

Query  130  KPGTSVDVLFELAPHLD--MALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGG  187
                +V  L + A  LD   A  + V  G+  Q   +  +  + T+++   +  + V GG
Sbjct  108  VDMIAVQDLEKRAKELDEMGADYIAVHTGYDLQAEGQSPLESLRTVKSVIKNSKVAVAGG  167

Query  188  LGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVS  228
            +  +TI +      ++++ G  +  A DP +     +  + 
Sbjct  168  IKPDTIKEIVAESPDLVIVGGGIANADDPVEAAKQCRAAIE  208


>gi|81649887|sp|Q6GBR7|HPS_STAAS  3-hexulose-6-phosphate synthase (HPS) (D-arabino-3-hexulose-6-phosphate 
formaldehyde lyase)
 gi|81651682|sp|Q6GJ99|HPS_STAAR  3-hexulose-6-phosphate synthase (HPS) (D-arabino-3-hexulose-6-phosphate 
formaldehyde lyase)
 gi|81762794|sp|Q8NXX1|HPS_STAAW  3-hexulose-6-phosphate synthase (HPS) (D-arabino-3-hexulose-6-phosphate 
formaldehyde lyase)
Length=210

 Score = 98.4 bits (244),  Expect = 2e-20, Method: Composition-based stats.
 Identities = 39/221 (17%), Positives = 79/221 (35%), Gaps = 20/221 (9%)

Query  11   LASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTE  70
            LA D  N   +  ++ N   D          +V  + +G PI+      +P     ++  
Sbjct  5    LAIDLLN-KEDAAELANKVKD----------YVDIVEIGTPII--YNEGLPAVKHMADNI  51

Query  71   KKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQ-DPLHLVKLIKSKGIKAACAI  129
                   D  +M +  +  V    K GAD  T    A        ++       +    +
Sbjct  52   SNVKVLADMKIM-DAADYEVSQAIKFGADVITILGVAEDASIKAAIEEAHKNNKQ---LL  107

Query  130  KPGTSVDVLFELAPHLD--MALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGG  187
                +V  L + A  LD   A  + V  G+  Q   +  +  + T+++   +  + V GG
Sbjct  108  VDMIAVQDLEKRAKELDEMGADYIAVHTGYDLQAEGQSPLESLRTVKSVIKNSKVAVAGG  167

Query  188  LGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVS  228
            +  +TI +      ++++ G  +  A DP +     +  + 
Sbjct  168  IKPDTIKEIVAESPDLVIVGGGIANADDPVEAAKQCRAAIE  208